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Basic propensity score methodology is designed to balance the distributions of multivariate pre-treatment covariates when comparing one active treatment with one control treatment. However, practical settings often involve comparing more than two treatments, where more complicated contrasts than...
Formal guidelines for statistical reporting of non-randomized studies are important for journals that publish results of such studies. Although it is gratifying to see some journals providing guidelines for statistical reporting, we feel that the current guidelines that we have seen are not...
Geographical regions may have an influence on asthma exacerbation. No conclusive study has been conducted to fully support or dissipate this assertion. We sought to use a data-driven approach to investigate the possible effect of geographical location on asthma. This study was based on data...
Due to the globalization of drug development, multi-regional clinical trials (MRCTs) have been increasingly adopted in clinical evaluations. In MRCTs, the primary objective is to demonstrate the efficacy of new drugs in all participating regions, but heterogeneity of various relevant factors...
Case fatality risk (CFR) is the probability of death among cases of a disease. A crude CFR estimate is the ratio of the number deaths to the number of cases of the disease. This estimate is biased, however, particularly during outbreaks of emerging infectious diseases such as COVID-19, because...
Epidemiological modeling is an important problem around the world. This research presents COVID-19 analysis to understand which model works better for different regions. A comparative analysis of three growth curve fitting models (Gompertz, Logistic, and Exponential), two mathematical models...
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