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Because every species has unique attributes relevant to understanding specific aspects of aging, using a diversity of study systems and a comparative biology approach for aging research has the potential to lead to novel discoveries applicable to human health. Monogonont rotifers, a standard...
The concept of frailty refers to heterogeneity in the risk of adverse outcomes for people of the same age. It is traditionally thought of as the inability of the body to maintain homeostasis. It can help explain differences between chronological and biological age and can quantify healthspan in...
BACKGROUND:Quercetin is a flavonoid with reported antioxidant, anti-inflammatory and anti-aging effects, and may limit muscle wasting in cancer cachexia.OBJECTIVE:To investigate the effect of quercetin on muscle wasting in the murine C26 cancer-cachexia model and assess the feasibility of...
BACKGROUND:Older adults, both institutionalized and free-living are vulnerable to nutritional deficiencies and poor nutritional status, which affect morbidity and quality of life amongst them. Yet, little attention on nutritional needs is given to this vulnerable group in many developing...
BACKGROUND:Strategies to reduce osteoarthritis (OA) symptoms and increase physical function in persons with lower extremity (LE) OA is a public health priority.OBJECTIVE:To examine associations between diet quality and measures of physical function among overweight and obese older adults with...
BACKGROUND:Cocoa, one of the richest dietary sources of polyphenols has been studied for its health promoting effects, but how long-term consumption of cocoa affects age-associated health and lifespan is not well defined.OBJECTIVE:The objective of this study was to determine the effects of...
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