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doi: 10.1001/jamapsychiatry.2024.0084pmid: 38477905
This Viewpoint discusses biological aging and mental illness.
van ’t Wout-Frank, Mascha; Arulpragasam, Amanda R.; Faucher, Christiana; Aiken, Emily; Shea, M. Tracie; Jones, Richard N.; Greenberg, Benjamin D.; Philip, Noah S.
doi: 10.1001/jamapsychiatry.2023.5661pmid: 38446471
Key PointsQuestionCan therapeutic exposure using virtual reality (VR) be augmented with simultaneously applied transcranial direct current stimulation (tDCS) to reduce symptoms of posttraumatic stress disorder (PTSD)? FindingsIn this randomized clinical trial including 54 US military veterans with warzone-related trauma, active tDCS delivered during VR exposure significantly improved self-reported PTSD symptoms, reduced measures of autonomic arousal, and improved social functioning compared with sham stimulation during VR exposure. This trial replicated key findings from a prior pilot study. MeaningThese findings suggest that the use of combined VR exposure plus tDCS could be a promising treatment for warzone-related PTSD.
van der Ven, Els; Olino, Thomas M.; Diehl, Katharina; Nuñez, Stephanie M.; Thayer, Griffin; Bridgwater, Miranda A.; Ereshefsky, Sabrina; Musket, Christie; Lincoln, Sarah Hope; Rogers, R. Tyler; Klaunig, Mallory J.; Soohoo, Emily; DeVylder, Jordan E.; Grattan, Rebecca E.;
Skampardoni, Ioanna; Nasrallah, Ilya M.; Abdulkadir, Ahmed; Wen, Junhao; Melhem, Randa; Mamourian, Elizabeth; Erus, Guray; Doshi, Jimit; Singh, Ashish; Yang, Zhijian; Cui, Yuhan; Hwang, Gyujoon; Ren, Zheng; Pomponio, Raymond; Srinivasan, Dhivya;
Lee, Maria; Cernvall, Martin; Borg, Jacqueline; Plavén-Sigray, Pontus; Larsson, Cornelia; Erhardt, Sophie; Sellgren, Carl M.; Fatouros-Bergman, Helena; Cervenka, Simon
doi: 10.1001/jamapsychiatry.2024.0016pmid: 38416480
This systematic review and meta-analysis investigates cognitive function and variability before initiation of antipsychotic medication in patients with first-episode psychosis compared with controls.
Suarez, Elizabeth A.; Bateman, Brian T.; Hernandez-Diaz, Sonia; Straub, Loreen; McDougle, Christopher J.; Wisner, Katherine L.; Gray, Kathryn J.; Pennell, Page B.; Lester, Barry; Zhu, Yanmin; Mogun, Helen; Huybrechts, Krista F.
Koga, Hayami K.; Grodstein, Francine; Williams, David R.; Manson, JoAnn E.; Tindle, Hilary A.; Shadyab, Aladdin H.; Michael, Yvonne L.; Saquib, Nazmus; Naughton, Michelle J.; Guimond, Anne-Josee; Kubzansky, Laura D.
Showing 1 to 10 of 20 Articles
doi: 10.1001/jamapsychiatry.2023.5497pmid: 38381422
This systematic review and meta-analysis investigates if ethnoracial groups in the US differ in risk of schizophrenia and other psychotic disorders, clinical high risk for psychosis, and psychotic symptoms and experiences.
doi: 10.1001/jamapsychiatry.2023.5599pmid: 38353984
This cohort study investigates the patterns of morphological brain changes that are reproducibly detectable with artificial intelligence (AI) in cognitively unimpaired populations and their genetic, clinical, lifestyle, and cognitive features.
Key PointsQuestionIs prescription stimulant treatment for attention-deficit/hyperactivity disorder during pregnancy associated with neurodevelopmental disorders in children? FindingsIn this cohort study including 7065 pregnancies exposed to amphetamine/dextroamphetamine and 1123 pregnancies exposed to methylphenidate in the second half of pregnancy, neither medication was associated with autism spectrum disorder, attention-deficit/hyperactivity disorder, or a composite of any neurodevelopmental disorder in children after careful adjustment for confounding by indication through various design and analytic approaches. MeaningThese findings suggest that amphetamine/dextroamphetamine and methylphenidate exposure during pregnancy are not likely to meaningfully increase the risk of childhood neurodevelopmental disorders.
This cohort study investigates the association of optimism with age-related changes in performance-based measures of physical functioning.