journal article
LitStream Collection
Montelukast Use and the Risk of Neuropsychiatric Adverse Events in Children
Wintzell, Viktor; Brenner, Philip; Halldner, Linda; Rhedin, Samuel; Gong, Tong; Almqvist, Catarina
2025 JAMA Pediatrics
doi: 10.1001/jamapediatrics.2024.5429
Key PointsQuestionIs use of montelukast associated with an increased risk of neuropsychiatric adverse events in children and adolescents? FindingsIn this cohort study of 26 462 montelukast users and 47 829 long-acting β-agonist users aged 6 to 17 years, there was no association between montelukast and the risk of neuropsychiatric adverse events. MeaningAggregated results from this large-scale observational analysis and other studies can inform clinical practice and support the management of asthma and allergic rhinitis in children and adolescents.