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ImportancePostnatally acquired cytomegalovirus (CMV) is typically benign in term infants but in very low-birth-weight (VLBW) infants can cause pneumonitis and sepsislike illness. Whether postnatal CMV infection results in long-term pulmonary sequelae in these infants is unknown.
ImportanceType 1 diabetes mellitus is one of the most common chronic diseases with onset in childhood, but environmental risk factors have not been convincingly established.
ObjectiveTo test whether increased growth during the first year of life is associated with higher risk of childhood-onset...
ImportanceThere is a well-described association between maternal diabetes mellitus and risk of congenital heart disease (CHD) in offspring. Although the clinical diagnoses of type 2 diabetes or gestational diabetes are strong risk factors for CHD, subclinical abnormalities of glucose and insulin...
This Viewpoint explores the topic of overtreatment and its ethical and financial effects on health care and contribution to waste in the health care system.
Adenotonsillectomy is one of the most common surgical procedures performed in children, with more than half a million procedures performed annually. We provide a review of the procedure, including indications, contraindications, perioperative issues, and current controversies. A more in-depth...
This Viewpoint discusses the need to develop additional infrastructure and new models of care to treat adults with childhood-onset illnesses in a safe, standardized, and evidence-based manner.
A premature male newborn with hemolysis, elevated liver enzymes, and low platelets syndrome, acute respiratory distress, and anemia developed a 0.5-cm, circular, crusted papule with a surrounding rim of erythema on the left hip. What is your diagnosis?
ImportanceEvery state in the United States has passed legislation for sport-related concussion, making this health issue important for physicians and other health care professionals. Safely returning athletes to sport after concussion relies on accurately determining when their symptoms...
ImportanceCognitive delay is the most common form of impairment among children born very preterm (VPT) at 32 weeks or less or with very low birth weight (VLBW) of 1250 g or less. It is important to identify factors that are robust predictors of long-term outcome because the ability to predict...
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