American journal of diseases of children

NICCUM, W. L.; JACKSON, R. L.; STEARNS, GENEVIEVE

1953 American journal of diseases of children

doi: 10.1001/archpedi.1953.02050080566001pmid: 13103769

THE INCIDENCE of deficiency disease in infants has decreased concurrently with increase and dissemination of nutritional knowledge. However, hypochromic anemia continues to occur commonly in the latter half of the first year of life. It is desirable, therefore, to prevent rather than treat hypochromic anemia. This study was undertaken to determine the amount and form of iron needed for this purpose. Since the studies of Elvehjem and co-workers,1 Stearns and co-workers,2 Heath and Patek,3 and McClean,4 iron preparations have been employed more frequently during the early months of postnatal life to prevent depletion of iron stores and to insure the availability of sufficient iron to maintain optimum hemoglobin values during infancy. Various amounts and types of iron have been advised as a daily dose. McClean4 recommends 50 to 60 mg. of iron daily as ferrous sulfate; Elvehjem, 25 mg. of iron daily as ferric pyrophosphate

EINSEL, I. HENRY; BOWMAN, R. E.; KOLETSKY, SIMON

1953 American journal of diseases of children

doi: 10.1001/archpedi.1953.02050080581002pmid: 13103770

TUMORS childhood are always interesting because one feels that the cause of tumor may eventually be solved by the careful study of these cases. Malignant tumors especially attract one's attention and study. We feel that in very young children, no matter what organ may be involved, the cases should be recorded in detail so that eventually the mass of material assembled will help in giving leads that will solve this problem. Dargeon,1 of New York, states that in 1940 Kelly reported that among 434 cases of malignant ovarian tumor observed at Memorial Hospital in New York none had occurred before the age of 10 years and only 4 between the ages of 10 and 15 years. Dargeon goes on to discuss 14 previously unreported cases, four in children under 10 years of age, one in a child one year of age. The last was a case of mesonephric adenosarcoma.

PICKERING, DONALD E.; FISHER, DELBERT A.; SCOTT, KENNETH G.; VAN WAGENEN, GERTRUDE; SMYTH, FRANCIS SCOTT

1953 American journal of diseases of children

doi: 10.1001/archpedi.1953.02050080587003pmid: 13103771

As one of a series of integrated reports regarding the role of thyroid in growth and metabolism of normal and I131 thyroid-ablated infant rhesus monkeys,1 this communication presents quantitative aspects of iodine metabolism. Earlier reports of thyroid function in rhesus monkeys are limited to observations on thyroidectomized mature animals,2 except in the study of Fleischmann and (Footnotes continued on next page) co-workers,2a where two 8-month-old animals were also observed. Of the reported studies,2 none have dealt with iodine metabolism per se, nor have they been concerned with the role of thyroid in growth and development. In all cases, thyroidectomy was achieved either by prolonged administration of thiouracil3 or by surgical means—the latter frequently being complicated by severe and often fatal hypoparathyroidism.4 When thiouracil was used, large doses (0.8 gm. per day) were found necessary to produce hypothyroidism and thyroid hyperplasia in adult animals,

ECKENHOFF, JAMES E.

1953 American journal of diseases of children

doi: 10.1001/archpedi.1953.02050080600004pmid: 13103772

SOME POSSIBLE deleterious effects of hospitalization and surgical operations on the personalities of children have been described.1 However, apparently there has been no attempt to relate the experiences of the induction period of anesthesia to the development of undesirable personality changes afterward. It is difficult to establish precise relationships, because the experiences of hospitalization, anesthetization, and operation are not easily separated. A recent study of the effect preanesthetic medication has upon the course of anesthesia2 has led to an investigation of possible relationship between anesthesia and personality changes. Over an 18-month period, questionnaires were mailed to the parents of all children admitted to the Hospital of the University of Pennsylvania for an otolaryngological operation. Answers were sought to the following questions: 1. Is your child a bed-wetter; since operation does he wet the bed or wet it more frequently? 2. Does your child have night cries or terrors;

BUMBALO, THOMAS S.; GUSTINA, FRANCIS J.; BONA, JOSEPH; OLEKSIAK, ROSE E.

1953 American journal of diseases of children

doi: 10.1001/archpedi.1953.02050080605005pmid: 13103773

THE HIGH incidence of pinworm infection, in both children and adults, has been reported from all parts of the world. It is estimated that there are 209,000,000 cases of pinworm infection throughout the world.1 The incidence among school children varies considerably in different areas. Stoll and co-workers2 reported the lowest incidence, 1%, in Guam school children. Sutliff and Echandi3 reported an incidence of 4.3% in hospitalized children in San Jose, Costa Rica. Killingsworth and co-workers4 reported an incidence of 32% in Port Arthur and Houston, Texas. Askue (personal communication) reports an incidence of 30% in clinic and hospitalized children in Philadelphia. Kuitunen-Ekbaum5 reported an incidence of 60% in Toronto, Canada, children. Cristovao6 in a study of 309 children in Sao Paulo, Brazil, found 60% infected. Voplenko7 in a study of 6,552 Russian children reported a low incidence of 17%. The incidence reported from

McREYNOLDS, WILLIAM U.; HAVENER, WILLIAM H.; PETROHELOS, MANOS A.

1953 American journal of diseases of children

doi: 10.1001/archpedi.1953.02050080614006pmid: 13103774

OPTIC NEURITIS accompanying encephalitis is a rare but well-established complication of smallpox and antirabic vaccination.1 Optic neuritis without central symptoms is, however, an extremely rare complication of immunization procedures. Duke-Elder,2 noting the reports of Cormack and Anderson 3 and Hasabe,4 states that "a severe neuritis without necessarily other central symptoms but involving abolition of light may follow an antirabic inoculation." In 1949, Ross5 decribed one case and Siegert6 three cases of bilateral optic neuritis following the administration of diphtheria toxoid. Following is the report of a case of bilateral optic neuritis which followed simultaneous smallpox vaccination and combined diphtheria-tetanus toxoid administration. REPORT OF CASE A 7-year-old white girl was brought to the hospital on May 13, 1952, complaining of a sudden decrease in visual acuity of three days' duration. She had no other complaints, and her parents had noted no symptoms of any illness. Further

MAISEL, JEROME E.; LAMM, STANLEY S.

1953 American journal of diseases of children

doi: 10.1001/archpedi.1953.02050080617007pmid: 13103775

BRAIN tumors occur infrequently during the first years of life and usually are not recognized as such prior to surgical exploration or autopsy examination. In a recent hospital admission an infant was observed who presented signs and symptoms suggestive of a lesion in the cerebellopontine region. These findings, to be described more fully later, led to a presumptive diagnosis of a brain tumor which was later confirmed at autopsy. REPORT OF CASE G. W., an 11-month-old Negro girl, was admitted to Kings County Hospital (State University Division) on Oct. 27, 1951, because of a stiff neck of one day's duration. Approximately two weeks prior to admission the infant became anorectic, showed evidence of weight loss, and reacted with increased irritability on being handled. Three days prior to admission the mother observed that the infant had become less irritable, moderately lethargic, and unresponsive to environmental stimuli. No history of fever, cough,

Mcquarrie, Irvine

1953 American journal of diseases of children

doi: 10.1001/archpedi.1953.02050080622008

Ward, Robert; Gellis, Sydney S.

1953 American journal of diseases of children

doi: 10.1001/archpedi.1953.02050080647009

1953 American journal of diseases of children

doi: 10.1001/archpedi.1953.02050080679010