Shafer, Brian M.; Lee, Vivian; Mehta, Sonul
2019 JAMA Ophthalmology
doi: 10.1001/jamaophthalmol.2018.5792pmid: 31393543
This caser report describes a hornlike, rubbery lesion over the right eyebrow of an elderly patient.
Gupta, Sonali; Jain, Shreyans; Kumar, Vinod
2019 JAMA Ophthalmology
doi: 10.1001/jamaophthalmol.2018.5539pmid: 31393541
This case report describes a teenaged patient with benign fleck retina.
Reed, Donovan Stephen; Mehta, Aditya; Drayna, Paul
2019 JAMA Ophthalmology
doi: 10.1001/jamaophthalmol.2018.5512pmid: 31393540
This case report describes a 42-year-old man who presented with isolated racemose angioma.
Gupta, Gaurav; Jain, Arun Kumar; Jurangal, Ajay
2019 JAMA Ophthalmology
doi: 10.1001/jamaophthalmol.2018.5744pmid: 31393542
This case report describes a 22-year-old woman who presented with persistent pupillary membrane that had a spiderlike appearance.
Grassmann, Felix; Harsch, Sebastian; Brandl, Caroline; Kiel, Christina; Nürnberg, Peter; Toliat, Mohammad R.; Fleckenstein, Monika; Pfau, Maximilian; Schmitz-Valckenberg, Steffen; Holz, Frank G.; Chew, Emily Y.; Swaroop, Anand; Ratnapriya, Rinki; Klein, Michael L.; Mulyukov, Zufar; Zamiri, Parisa; Weber, Bernhard H. F.
2019 JAMA Ophthalmology
doi: 10.1001/jamaophthalmol.2019.1318pmid: 31120506
Key PointsQuestionAre there common genetic variants contributing to progression of geographic atrophy secondary to age-related macular degeneration? FindingsThis pooled analysis combines data from 4 independent studies assessing progression of geographic atrophy secondary to age-related macular degeneration. The correlation between square root–transformed geographic atrophy growth rate and more than 7 million genetic variants was estimated, and 2 gene loci with genome-wide significance were identified as geographic atrophy progression–associated candidates: protein arginine methyltransferase 6 (chromosome 1) and lanosterol synthase (chromosome 21). MeaningGene prioritization within 2 identified loci as geographic atrophy progression–associated candidates, providing a basis for future functional studies exploring mechanisms of atrophic lesion growth.
Chellappa, Sarah L.; Bromundt, Vivien; Frey, Sylvia; Steinemann, Alexandra; Schmidt, Christina; Schlote, Torsten; Goldblum, David; Cajochen, Christian
2019 JAMA Ophthalmology
doi: 10.1001/jamaophthalmol.2019.1406pmid: 31120477
This cross-sectional study assesses whether intraocular cataract lens replacement in older patients with previous cataract is associated with the beneficial light effects on the circadian system, cognition, and sleep regulation.
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