Association Between Vessel Density and Visual Acuity in Patients With Diabetic Retinopathy and Poorly Controlled Type 1 DiabetesDupas, Bénédicte; Minvielle, Wilfried; Bonnin, Sophie; Couturier, Aude; Erginay, Ali; Massin, Pascale; Gaudric, Alain; Tadayoni, Ramin
2018 JAMA Ophthalmology
doi: 10.1001/jamaophthalmol.2018.1319pmid: 29800967
Key PointsQuestionWhat is the association between macular vessel density as measured by optical coherence tomography angiography and visual acuity in patients with diabetic retinopathy and poorly controlled type 1 diabetes?
FindingsIn a cohort study of 22 eyes of 22 patients with type 1 diabetes and diabetic retinopathy without macular edema, 41% had decreased vision. Vessel density was lower in eyes with diabetic retinopathy and decreased vision than in eyes with diabetic retinopathy and normal vision; loss of vessel density was greater in the deep capillary complex, particularly the deep capillary plexus, than in the superficial vascular plexus.
MeaningThese findings suggest that decreased vision in patients with diabetic retinopathy may be associated with the degree of capillary loss in the deep capillary complex.