Archives of Dermatology

Burrows, William M.;Stoughton, Richard B.

1976 Archives of Dermatology

doi: 10.1001/archderm.1976.01630260003001

Abstract • Ten healthy human volunteers were exposed to a primary sensitizing dose of 1 mg dinitrochlorobenzene (DNCB) by an open topical technique within an area that had been pretreated with a potent topical glucocorticosteroid compound. Quantitative elicitation testing was performed on the opposite side by an open patch test technique two weeks after the sensitizing application. One (10%) of the ten subjects became sensitized. A matched control group of ten subjects was similarly sensitized without steroid treatment. Eight (80%) of the ten became sensitized. One month later, five of the eight test subjects in whom sensitization had been prevented were retested in an identical fashion without steroid pretreatment, to determine if any degree of tolerance had been induced. All five subjects became sensitized. Topical glucocorticosteroids inhibited the development of sensitization to topically applied DNCB. Tolerance was not induced by this single process. (Arch Dermatol 112:175-178, 1976) References 1. Claman HN: Corticosteroids and lymphoid cells . New Engl J Med 287:388-397, 1972.Crossref 2. Balow JE, Rosenthal AS: Glucocorticoid suppression of macrophage migration inhibitory factor . J Exp Med 137:1031-1041, 1973.Crossref 3. Weston WL, Claman HN, Kruegar GG: Site of action of cortisol in cellular immunity . J Immunol 110:880-883, 1973. 4. Zurier RB, Weissman G: Antiimmunologic and antiinflammatory effects of steroid therapy . Med Clin North Am 57:1295-1307, 1973. 5. deSousa M, Fachet J: The cellular basis of the mechanism of action of cortisone acetate on contact sensitivity to oxazolone in the mouse . Clin Exp Immunol 10:673-684, 1972. 6. Boss PS, Jolley WB, Ainsworth GJ: Mechanisms of action of topically applied triamcinolone acetonide in prolonging skin allograft and survival time . Transplantation 15:17-21, 1973.Crossref 7. North RJ: The action of cortisone acetate on cell-mediated immunity to infection . J Exp Med 134:1485-1500, 1971.Crossref 8. Cohen IR, Stavy L, Feldman M: Glucocorticoids and cellular immunity in vitro . J Exp Med 132:1055-1070, 1970.Crossref 9. Stavy L, Cohen IR, Feldman M: Stimulation of rat lymphocyte proliferation of hydrocortisone during the induction of cell-mediated immunity in vitro . Transplantation 17:173-179, 1974.Crossref 10. MacKenzie AW, Stoughton RB: Method for comparing percutaneous absorption of steroid . Arch Dermatol 86:608-610, 1962.Crossref 11. Vickers CFH: Stratum corneum reservoir for drugs , in Montagna W, Stoughton RB, Variscott E (eds): Pharmacology and the Skin . New York, Appleton-Century-Crofts Inc, 1972, pp 177-189. 12. Chase MW, Macher E: The fate of antigen in induction of delayed allergic responses , in Montagna W and Billingham R (eds): Immunology and the Skin . New York, Appleton-Century Crofts Inc, 1969, pp 63-93. 13. Pearson MN, Raffel S: Macrophage-digested antigen as inducer of delayed hypersensitivity . J Exp Med 133:494-505, 1971.Crossref 14. Asherson GL, Allison AC, Zembala M: Production of delayed hypersensitivity by antigen associated with peritoneal exudate cells and the effect of pretreatment with Freund's complete adjuvant . Immunology 22:465-473, 1972. 15. Tanioku K: The role of macrophages in the development of contact sensitivity . Acta Derm Venereol ( (Suppl) )73:187-188, 1973. 16. Baumgarten A, Geczy AF: Induction of delayed hypersensitivity by dinitrophenylated lymphocytes . Immunology 19:205-217, 1970. 17. Nakagawa S, Beki H, Taniokv K: The distribution of 2, 4-dinitrophenyl groups in guinea pig skin following surface application of 2, 4-dinitrochlorobenzene: An immunofluorescent study . J Invest Dermatol 57:269-277, 1971.Crossref 18. McFarlin DE, Balfour B: Contact sensitivity in the pig . Immunology 25:995-1009, 1973.

Hubler, Winthrope R.;Clabaugh, West

1976 Archives of Dermatology

doi: 10.1001/archderm.1976.01630260007002

Abstract • Norwegian scabies is an ectoparasitic infestation by Sarcoptes scabiei, characterized by hyperkeratotic lesions of the hands, feet, ears, and scalp, which contain many mites. An epidemic of Norwegian scabies involved 22 patients in a 25-patient ward of mentally and physically handicapped persons (mostly mongoloids). The pathogenesis of the prolific mite population is unclear, but either a specific immunologic deficit or the inability to effectively eliminate the mites by scratching is a plausible possibility. (Arch Dermatol 112:179-181, 1976) References 1. Calnan CD: Crusted scabies . Br J Dermatol 62:71-78, 1950.Crossref 2. Sweitzer SE, Winer LH: Norwegian scabies . Arch Dermatol Syphilol 43:678-681, 1941.Crossref 3. Maguire HC Jr, Kligman AM: Norwegian scabies . Arch Dermatol 82:62-64, 1960.Crossref 4. Schiff BL, Ronchese F: Norwegian scabies . Arch Dermatol 89:236-238, 1964.Crossref 5. Kurtin SB, Leider M: Norwegian scabies: Report and lessons of a case . New Engl J Med 278:1099-1100, 1968.Crossref 6. Burks JW Jr, Jung RC, George WM: Norwegian scabies . Arch Dermatol 74:131-140, 1956.Crossref 7. Haydon JR Jr, Caplan RM: Epidemic scabies . Arch Dermatol 103:168-173, 1971.Crossref 8. Kocsard E: Scabies keratotica . Cutis 3:41-45, 1967. 9. Mellanby K: Scabies . Middlesex, England, EW Classey Ltd, 1972. 10. Prakken JR, van Vloten TJ: Allergy in scabies: Positive intracutaneous tests with antigen from scabies norvegica: Passive transfer of antibodies. (Prausnitz-Küstner) . Dermatologica 99:124-131, 1949.Crossref 11. Ingram JT: Ward epidemic from Norwegian scabies . Br J Dermatol 63:311-317, 1951.Crossref

Resh, William;Stoughton, Richard B.

1976 Archives of Dermatology

doi: 10.1001/archderm.1976.01630260010003

Abstract • Topical antibiotics were used on patients with acne vulgaris. Corynebacterium acnes organisms from open comedones were quantitated during treatment, and the progress of the disease was evaluated. Clindamycin lotion completely suppressed the growth of C acnes organisms, whereas erythromycin and tetracycline did not depress the C acnes counts. Taken as a group, these antibiotics gave a substantial improvement of the disease on the treated side as compared with paired untreated sides of the face and back. (Arch Dermatol 112:182-184, 1976) References 1. Unna PG: The Histopathology of the Diseases of the Skin . N Walker (trans), New York, MacMillan Company, 1896. 2. Marples MJ: The Ecology of the Human Skin . Springfield, Ill, Charles C Thomas, Publisher, 1965. 3. Shehadeh NH, Kligman AM: The bacteriology of acne . Arch Dermatol 88:829-831, 1963.Crossref 4. Reisner RM, Silver DZ, Puhvel M, et al: Lipolytic activity of Corynebacterium acnes . J Invest Dermatol 51:190-196, 1968.Crossref 5. Kirschbaum JO, Kligman AM: The pathogenic role of Corynebacterium acnes in acne vulgaris . Arch Dermatol 88:832-833, 1963.Crossref 6. Izumi AK, Marples R, Kligman AM: Bacteriology of acne comedones . Arch Dermatol 102:397-399, 1970.Crossref 7. Marshall JH, Kelsey JC: A standard culture medium for general bacteriology . J Hyg 58:367-372, 1960.Crossref 8. Fulton JE, Pablo G: Topical antibiotic therapy for acne: Study of the family of erythromycins . Arch Dermatol 110:83-86, 1974.Crossref

Penneys, Neal S.;Eaglstein, William H.;Frost, Philip

1976 Archives of Dermatology

doi: 10.1001/archderm.1976.01630260013004

Abstract • Fourteen of 15 patients with pemphigus have responded successfully to systemically administered gold therapy for up to four years. Eight of the 15 (56%) are in remission, requiring no therapy (mean, 21 months). The remaining seven patients are receiving maintenance systemic gold therapy. Only one instance of toxicity was seen during maintenance therapy. The high remission rate associated with gold therapy and the infrequent side-effects during maintenance therapy suggest that systemically given gold therapy may be the treatment of choice for the management of pemphigus, following initial therapy with corticosteroids when necessary. (Arch Dermatol 112:185-187, 1976) References 1. Ryan JG: Pemphigus: A 20-year survey of experience with 70 cases . Arch Dermatol 104:14-20, 1971.Crossref 2. Krain LS: Pemphigus: Epidemiologic and survival characteristics of 59 patients, 1955-1973 . Arch Dermatol 110:862-865, 1974.Crossref 3. Lever WF, Goldberg HS: Treatment of pemphigus vulgaris with methotrexate . Arch Dermatol 100:70-78, 1969.Crossref 4. Roenigk HH, Deodhar S: Pemphigus treatment with azathioprine: Clinical and immunologic correlation . Arch Dermatol 107:353-357, 1973.Crossref 5. McKelvey EM, Hasegawa J: Cyclophosphamide and pemphigus vulgaris . Arch Dermatol 103:198-200, 1971.Crossref 6. Penneys NS, Eaglstein WH, Indgin S, et al: Gold sodium thiomalate treatment of pemphigus . Arch Dermatol 108:56-60, 1973.Crossref 7. Freyberg RH: Gold therapy in rheumatoid arthritis , in Hollander JL, McGarty DJ (eds): Arthritis and Allied Conditions . Philadelphia, Lea & Febiger, 1972, p 470. 8. Keenan J, Thompson JB, Chamberlain MA, et al: Prolonged corticotrophic action of a synthetic substituted 1-18ACTH . Br Med J 3:742-743, 1971.Crossref 9. Soler-Bechara J, Rammerer WD, Rogdoff B, et al: Maintenance gold therapy for rheumatoid arthritis—Analysis of effectiveness in 167 patients , abstracted. Arthritis Rheum 8:469-470, 1965. 10. Persellin RH, Hess EV, Ziff M: Effect of a gold salt on the immune response . Arthritis Rheum 10:99-105, 1967.Crossref 11. Penneys NS, Ziboh V, Gottlieb NL, et al: Inhibition of prostaglandin synthesis and human epidermal enzymes by aurothiomalate in vitro: Possible actions of gold in pemphigus . J Invest Dermatol 63:356-361, 1974.Crossref 12. Gottlieb NL, Smith PM, Penneys NS, et al: Gold concentrations in hair, nail, and skin during chrysotherapy . Arthritis Rheum 17:56-62, 1974.Crossref 13. Gottlieb NL, Smith PM, Smith EM: Tissue gold concentrations in a rheumatoid arthritic receiving chrysotherapy . Arthritis Rheum 15:16-22, 1972.Crossref

Espy, Paul D.;Jolly, Henry W.

1976 Archives of Dermatology

doi: 10.1001/archderm.1976.01630260017005

Abstract • Norwegian scabies is rare yet distinctive. The majority of reported cases have been in patients with a relatively small group of diseases, including Down syndrome and lepromatous leprosy. A case occurred in a patient on long-term immunosuppressive therapy following a kidney transplant. Altered host factors appear to be the prime determinants in the pathogenesis of the disease. (Arch Dermatol 112:193-196, 1976) References 1. Wilkinson DS: Norwegian (crusted) scabies . Br J Dermatol 65:31, 1953. 2. Kocsard E, et al: Scabies crustosa (scabies Norvegica) in Mongols . Aust J Dermatol 5:235-240, 1959.Crossref 3. Maguire HC Jr, Kligman AM: Norwegian scabies . Arch Dermatol 82:62-64, 1960.Crossref 4. Hyman D: Psoriatic-like lesions in Norwegian scabies . Cutis 11:336, 1973. 5. Anderson NP, Stout M: Norwegian scabies . Arch Dermatol Syph 42:499-500, 1940. 6. Bedi BMS: Norwegian scabies (a clinical study) . Indian J Dermatol 17:76-78, 1972. 7. Short B, Derrick EH: A remarkable case of scabies . Med J Aust 1:621, 1948. 8. Anderson I: Norwegian scabies . Br Med J 2:25, 1952.Crossref 9. Dostrovsky A, et al: Scabies Norvegica and lymphatic leukemia . Dermatologica 113:26-34, 1956.Crossref 10. Tanaka T, Usuba M: Scabies Norvegica associated with leukemia cutis . Tohoku J Exp Med 72:35-41, 1960.Crossref 11. Herridge CF: Norwegian scabies (crusted scabies) . Br Med J 1:239-240, 1963.Crossref 12. Logan JC, et al: Norwegian scabies and lymphatic leukemia . Br J Dermatol 79:303-305, 1967.Crossref 13. Walshe MM: Norwegian scabies . West Indian Med J 16:57-61, 1967. 14. Macmillan AL: Unusual features of scabies associated with topical fluorinated steroids . Br J Dermatol 87:496-497, 1972.Crossref 15. Paterson WD, et al: Norwegian scabies during immunosuppressive therapy . Br Med J 4:211-212, 1973.Crossref 16. Norwegian scabies during immunosuppressive therapy . Br Med J 4:485-486, 1973. 17. Evans DI: Norwegian scabies and monocytic leukemia . Br Med J 4:613, 1973.Crossref 18. Ingram JT: Ward epidemic from Norwegian scabies . Br J Dermatol 63:311-317, 1951.Crossref 19. Burks JW, et al: Norwegian scabies . Arch Dermatol 74:131-140, 1956.Crossref 20. George WM: Norwegian scabies . Arch Dermatol 78:320-324, 1958.Crossref 21. Johnson CG, Mellanby K: Parasitology of human scabies . Parasitology 34:285-290, 1942.Crossref 22. Hessler R: An extreme case of parasitism . Am Naturalist 27:346-352, 1893.Crossref 23. Pirila V, et al: Scabies Norvegica . Arch Derm Venereol 47:267-268, 1967. 24. Haydon JR Jr, Caplan RM: Epidemic scabies . Arch Dermatol 103:168-173, 1971.Crossref 25. Mellanby K: Scabies . London, Oxford University Press, 1943. 26. Mellanby K: The development of symptoms, parasitic infection and immunity in human scabies . Parasitology 35:197-206, 1944.Crossref 27. Heilesen B: Acarus scabiei and scabies . Acta Derm Venereol 26( (suppl 14) ):1-370, 1946. 28. Summons J: A case of Norwegian scabies . Aust J Dermatol 8:44-47, 1965.Crossref 29. Prakken JR, Van Vloten TJ: Allergy in scabies . Dermatologica 99:124-131, 1949.Crossref 30. Kurtin SB, Leider M: Norwegian scabies: Report and lessons of a case . N Engl J Med 278:1099-1100, 1968.Crossref 31. Marples MJ: Ecology of Human Skin . Springfield, Ill, Charles C Thomas Publisher, 1965, pp 324-325.

Rau, Robert C.;Dubin, Howard V.;Taylor, William B.

1976 Archives of Dermatology

doi: 10.1001/archderm.1976.01630260021006

Abstract • Oriental sore (acute cutaneous leishmaniasis) is usually a self-limited infection of the skin caused by the protozoan Leishmania tropica. This disease is endemic to the Mediterranean, Asia, Africa, and the Middle East, and is seen in this country among travellers and immigrants. We found four cases at the University of Michigan and diagnosed and treated the disorder. Some of the treatments currently recommended for this disease are potentially toxic, and none have been proved to be of real value. Uncomplicated, acute cutaneous leishmaniasis (L tropica) may best be managed by withholding treatment and observing the patient. (Arch Dermatol 112:197-201, 1976) References 1. Hambrick GW, Even-Paz Z: Cutaneous leishmaniasis encountered in Philadelphia . JAMA 198:101-105, 1966.Crossref 2. Hart M, et al: Late cutaneous leishmaniasis . Arch Dermatol 99:455-458, 1969.Crossref 3. Szymanski FJ: Cutaneous leishmaniasis . Arch Dermatol 85:550-551, 1962.Crossref 4. Tilley RF: Cutaneous leishmaniasis . Arch Dermatol 90:240, 1964. 5. Newman BA, Promerantz LM: Disseminated cutaneous leishmaniasis (tropica) . Arch Dermatol 98:105-106, 1968.Crossref 6. Palitz LL: Diagnosis: Cutaneous leishmaniasis (treated with dihydrostreptomycin) . Arch Dermatol 80:102, 1959.Crossref 7. Farah FS, Malak JA: Cutaneous leishmaniasis . Arch Dermatol 103:467-474, 1971.Crossref 8. Harman RRM: Parasitic worms and protozoa , in Rook A: Textbook of Dermatology . Oxford, England, Blackwell Scientific Publications, 1972. 9. Bray RS, Lainso R: The immunology and serology of leishmaniasis . Trans R Soc Trop Med Hyg 59:535-544, 1965.Crossref 10. Kurban AK: Cutaneous leishmaniasis . Leb Med J 18:381-386, 1965. 11. Harvey SC: Heavy metals , in Goodman L, Gilman A: The Pharmacological Basis of Therapeutics . London, The Macmillian Co, 1970. 12. Plorde JJ, Bennett IL: Leishmaniasis , in Wintrobe MM, et al: Harrison's Principles of Internal Medicine . New York, McGraw-Hill Book Co Inc, 1970. 13. Walton BC, et al: American cutaneous leishmaniasis . JAMA 228:1256-1258, 1974.Crossref 14. Long PI: Cutaneous leishmaniasis treated with metronidazole . JAMA 223:1378-1379, 1973.Crossref 15. Turk JL, Bryceson ADM: Immunological phenomena in leprosy and related disease . Adv Immunol 13:209-266, 1971. 16. Bryceson ADM: Diffuse cutaneous leishmaniasis in Ethiopia . Trans R Soc Trop Med Hyg 63:708-737, 1969.Crossref

Drake, Thomas E.;Maibach, Howard I.

1976 Archives of Dermatology

doi: 10.1001/archderm.1976.01630260026007

Abstract • A patient had acute stomatitis and dermatitis due to a popular toothpaste containing cinnamon oil flavor. Cinnamon cassia oil is known as a topical sensitizer and was demonstrated to be the offending allergen. Cinnamic aldehyde and related chemicals are used widely, so that patients having cinnamon allergy may be exposed to many sources. There is difficulty in diagnosing allergic contact stomatitis. (Arch Dermatol 112:202-203, 1976) References 1. Wilkinson D, Fregert S, et al: Terminology of contact dermatitis . Acta Derm Venereol 50:287, 1970. 2. Hjorth N: Eczematous allergy to balsam, allied perfumes and flavouring agents , Acta Derm Venereol 41 ( (suppl) ):46, 1961. 3. Hjorth N, Jervoe P: Allergisk Kontaktstomatitis og Kontaktdermatitis Fremdkalt af Smogstoffen i Tandpasta . Tandlaegebladet 71:937-942, 1967. 4. Loveman AB: Stomatitis venenata: Report of a case of sensitivity of mucous membranes and the skin to oil of anise . Arch Dermatol 37:70-81, 1938. 5. Papa CM, Shelley WB: Menthol hypersensitivity: Diagnostic basophil response in a patient with chronic urticaria, flushing and headache . JAMA 189:546, 1964.Crossref 6. Laubach J, Malkinson FD, Ringrose E: Chelitis caused by cinnamon oil (cassia) in toothpaste , JAMA 152:404, 1953.Crossref 7. Collins F, Mitchell JC: Aroma chemicals: Reference sources for perfume and flavour ingredients . Contact Dermatitis , to be published. 8. Bonnevie P: Some experience of war-time industrial dermatoses . Acta Derm Venereol . 28:231, 1948. 9. Millard LG, Contact sensitivity to toothpaste . Br Med J 1:676, 1973.Crossref 10. Kirton W, Wilkinson DS: Contact sensitivity to toothpaste . Br Med J 2:115-116, 1973.Crossref 11. Millard LG: Acute contact sensitivity to a new toothpaste . J Dentist 1:168-170, 1973.Crossref 12. Magnusson B, Kirton V, Wilkinson D: Toothpaste contact dermatitis . Contact Dermatitis , to be published.

Zimmerman, Michael R.;Clark, Wallace H.

1976 Archives of Dermatology

doi: 10.1001/archderm.1976.01630260028008

Abstract • Examination of the mummy of an Egyptian who died in 892 BC ± 53 years showed the skin to be well preserved, with inguinal subcorneal vesicles of the type seen in subcorneal pustular dermatosis. This condition apparently antedates by almost three millenia its description as a clinicopathological entity by Sneddon and Wilkinson in 1956. (Arch Dermatol 112:204-205, 1976) References 1. Sneddon IB, Wilkinson DS: Subcorneal pustular dermatosis . Br J Dermatol 68:385-394, 1956.Crossref 2. Budge EAW: The Mummy , ed 2. New York, Collier Books, 1972. 3. Ruffer MA: Studies in the Paleopathology of Egypt . Chicago, University of Chicago Press, 1921. 4. Zimmerman MR: Histological examination of experimentally mummified tissues . Am J Phys Anthropol 37:271-280, 1972.Crossref 5. Lever WF: Histopathology of the Skin , ed 4. Philadelphia, JB Lippincott Co, 1967, pp 129-131. 6. Giacometti L, Chiarelli B: The skin of Egyptian mummies: A study in survival . Arch Dermatol 97:712-713, 1968.Crossref 7. Post PW, Daniels F Jr: Histological and histochemical examination of American Indian scalps, mummies, and a shrunken head . Am J Phys Anthropol 30:269-294, 1969.Crossref 8. Ruffer MA, Ferguson AR: An eruption resembling that of variola in the skin of a mummy of the 20th Dynasty (1200-1100 B.C.) . J Pathol Bacteriol 15:1-2, 1911.Crossref 9. Smith GE: The Royal Mummies . Cairo, Musée de Caire, 1912. 10. Wilder HH: The restoration of dried tissues, with special reference to human remains . Am Anthropol 6:1-17, 1904.Crossref 11. Wells C: Pseudopathology , in Brothwell D, Sandison AT (eds): Diseases in Antiquity . Springfield, Ill, Charles C Thomas Publishers, 1967.

Greer, Kenneth E.;Bishop, Gregory F.;Ober, William C.

1976 Archives of Dermatology

doi: 10.1001/archderm.1976.01630260030009

Abstract • A 52-year-old patient was admitted to the hospital for evaluation of hypertension. He had two skin lesions, one on the forehead and one in the postauricular area, which had been present since birth. The forehead lesion was a nevus sebaceous and the postauricular lesion was a syringocystadenoma papilliferum. Except for a few patients with widespread nevus sebaceous and syringocystadenoma papilliferum associated with neurologic abnormalities, most of the previously reported patients with these nevi have had solitary lesions of one or the other. An association of nevus sebaceous and syringocystadenoma papilliferum in the same lesion is not uncommon. Despite bleeding and crusting in one of the lesions and despite informing the patient that a malignant neoplasm may develop in these nevi, he refused excision of either of the lesions. (Arch Dermatol 112:206-208, 1976) References 1. Jancar S: Nevus syringocystadenomatosus papilliferum with skull and brain lesions, hemiparesis, epilepsy and mental retardation . Br J Dermatol 82:402-405, 1970.Crossref 2. Feuerstein RC, Mims LC: Linear nevus sebaceous with convulsions and mental retardation . Am J Dis Child 104:675-679, 1962. 3. Wilson-Jones E, Heyl T: Nevus sebaceus . Br J Dermatol 82:99-117, 1970.Crossref 4. Mehregan AH, Pinkus H: Life history of organoid nevi . Arch Dermatol 91:574-588, 1965.Crossref 5. Helwig EB, Hackney VC: Syringadenoma papilliferum . Arch Dermatol 71:361-372, 1955.Crossref 6. Hashimoto K, Lever W: Appendage Tumors of the Skin . Springfield, Ill, Charles C Thomas Publisher, 1968, p 46. 7. Constant E, Davis DG: The premalignant nature of the sebaceous nevus of Jadassohn . Plast Reconstr Surg 50:257-259, 1972.Crossref

Mohs, Frederic E.

1976 Archives of Dermatology

doi: 10.1001/archderm.1976.01630260033010

Abstract • Complete microscopical control of the excision of cancer of the skin is achieved by removing tissues layer by layer and examining the undersurface of each layer by means of frozen sections. If the cancer is extensive and complicated or if it is of a type readily spread over an excisional surface, the tissues are fixed in situ with zinc chloride prior to excision (chemosurgery, fixed tissue technique). If the cancer is not too extensive or complicated, the tissues are excised in the fresh, unfixed state (chemosurgery, fresh tissue technique). Both techniques are highly reliable; for example, in two consecutive series of basal cell carcinomas treated chemosurgically, the five-year rate of cure was 99.3% for the 9,351 lesions removed by the fixed tissue technique and 97% for the 127 lesions removed by the fresh tissue technique. (Arch Dermatol 112:211-215, 1976) References 1. Mohs FE: Chemosurgery in Cancer, Gangrene and Infections . Springfield, Ill, Charles C Thomas Publisher, 1956. 2. Mohs FE, Guyer MF: Pre-excisional fixation of tissues in the treatment of cancer in rats . Cancer Res 1:49-51, 1941. 3. Mohs FE: Chemosurgery: A microscopically controlled method of cancer excision . Arch Surg 42:279-295, 1941.Crossref 4. Mohs FE: The chemosurgical method for the microscopically controlled excision of external cancer with reference to eyelid . Trans Am Acad Ophthalmol Otolaryngol 62:355-356, 1958. 5. Mohs FE: Chemosurgery for facial neoplasms . Arch Otolaryngol 95:62-67, 1972.Crossref 6. Tromovitch TA, Stegeman SJ: Microscopically controlled excision of skin tumors: Chemosurgery (Mohs): Fresh tissue technique . Arch Dermatol 110:231-232, 1974.Crossref 7. Mohs FE: Chemosurgical treatment of melanoma: A microscopically controlled method of excision . Arch Dermatol Syphilol 62:269-279, 1950.Crossref 8. Mohs FE: Prevention and treatment of skin cancer . Wis Med J 73:85-92, 1974.

Sams, W. Mitchell;Thorne, E. George;Small, Peter;Mass, Myron F.;McIntosh, Rawle M.;Stanford, Ray E.

1976 Archives of Dermatology

doi: 10.1001/archderm.1976.01630260039011

Abstract • Patients with leukocytoclastic vasculitis have purpuric, palpable lesions, most commonly on the lower part of the legs. Systemic involvement, particularly of the kidneys, is found frequently. Characteristic pathological features include necrosis of small vessels within the dermis, infiltration by polymorphonuclear leukocytes within and around the vessel walls, hemorrhage, and occasionally thrombosis. Immunofluorescence study frequently shows granular deposits of immunoglobulins and complement in vessel walls. Etiologic agents that have been implicated include infection, foreign proteins, chemicals, drugs, and a variety of diseases. The mechanism causing tissue damage is thought to be mediated by immune complexes, although specific antigens have only occasionally been unequivocally identified. Treatment includes bedrest, corticosteroids, and sometimes, cytotoxic agents. (Arch Dermatol 112:219-226, 1976) References 1. Kussmaul A, Maier R: Ueber eine bisher nicht beschriebene eigenthumliche Arterienerkrankung (periarteritis nodosa), die mit Morbus Brightii und rapid fortschreitender allgemeiner Muskellahmung einhergeht . Dtsch Arch Klin Med 1:484-517, 1866. 2. Zeek PM: Periarteritis nodosa: A critical review . Am J Clin Pathol 22:777-790, 1952. 3. Winkelmann RK, Ditto WB: Cutaneous and visceral syndromes of necrotizing or "allergic" angiitis: A study of 38 cases . Medicine 43:59-89, 1964.Crossref 4. Knowles HC Jr, Zeek PM, Blankenhorn MA: Studies on necrotizing angiitis: IV. Periarteritis nodosa and hypersensitivity angiitis . Arch Intern Med 92:789-805, 1953.Crossref 5. Ramsay C, Fry L: Allergic vasculitis: Clinical and histological features and incidence of renal involvement . Br J Dermatol 81:96-102, 1969.Crossref 6. Braverman IM: Skin Signs of Systemic Disease . Philadelphia, WB Saunders Co, 1970, p 199. 7. O'Duffy JD, Scherbel AL, Reidbord HE, et al: Necrotizing angiitis: A clinical review of twenty-seven autopsied cases . Clev Clin Q 32:87-98, 1965.Crossref 8. Norkin S, Weiner J: Henoch-Schönlein syndrome. Review of pathology and report of two cases . Am J Clin Pathol 33:55-65, 1960. 9. Allen DM, Diamond LK, Howell DA: Anaphylactoid purpura in children (Schönlein-Henoch syndrome) . Am J Dis Child 99:147-168, 1960.Crossref 10. McDuffie FC, Sams WM Jr, Maldonado JE, et al: Hypocomplementemia with cutaneous vasculitis and arthritis: Possible immune complex syndrome . Mayo Clin Proc 48:340-348, 1973. 11. Soter NA, Austen KF, Gigli I: Urticaria and arthralgias as manifestations of necrotizing angiitis (vasculitis) . J Invest Dermatol 63:485-490, 1974.Crossref 12. Sams WM Jr, Claman H, Kohler PF, et al: Human necrotizing vasculitis: Immunoglobulins and complement in vessel walls of lesions and normal skin . J Invest Dermatol 64:441-445, 1975.Crossref 13. Soter NA, Austen KF, Gigli I: The complement system in necrotizing angiitis of the skin: Analysis of complement component activities in serum of patients with concomitant collagenvascular diseases . J Invest Dermatol 63:219-226, 1974.Crossref 14. Goltz RW: Cutaneous manifestations of allergic angiitis . Lancet 82:219-222, 1962. 15. Cox AJ: Pathologic changes in hypersensitivity angiitis , in Helwig EB, Mostofi FK (eds): The Skin . Baltimore, Williams & Wilkins, 1971, pp 279-292. 16. Udaka K: The Arthus reaction , in Movat HZ (ed): Inflammation, Immunity, and Hypersensitivity . New York, Harper & Row Publishers, 1971, pp 389-423. 17. Venkatachalam MA, Cotran RS: Ultrastructure of local Arthus using horseradish peroxidase as antigen . Lab Invest 23:129-135, 1970. 18. Sabesin SM, Banfield WG: Electronmicroscopy of hypersensitivity Reactions: The Arthus phenomenon . Am J Pathol 42:551-569, 1963. 19. Ruiter M, Molehaar I: Ultrastructural changes in arteriolitis (vasculitis) allergica cutis superficialis . Br J Dermatol 83:14-26, 1970.Crossref 20. Perrot H, Leung TK, Leung J, et al: Etude ultrastructurale des lesions vasculaires dermiques du trisyndrome de Gougerot (vasculite leuococytoclasique) . Arch Dermatol Forsch 241:44-55, 1971.Crossref 21. Braverman IM, Yen A: Demonstration of immune complexes in spontaneous and histamine-induced lesions and in normal skin of patients with leukocytoclastic angiitis . J Invest Dermatol 64:105-112, 1975.Crossref 22. Rhodin JA: Ultrastructure of mammalian venous capillaries, venules, and small collecting veins . J Ultrastruct Res 25:452-500, 1968.Crossref 23. Majno G, Palade GE: Studies on Inflammation: I. The effect of histamine and serotonin on vascular permeability: An electromicroscopic study . J Biophys Biochem Cytol 11:571-605, 1961.Crossref 24. Mellors RC, Ortega LG: New observations on the pathogenesis of glomerulonephritis, lipid nephrosis, periarteritis nodosa, and secondary amyloidosis in man . Am J Pathol 32:455-499, 1956. 25. Stringa SG, Bianchi C, Casala AM, et al: Allergic vasculitis Gougerot-Ruiter syndrome: Immunofluorescent study . Arch Dermatol 95:23-27, 1967.Crossref 26. Scott DG, Rowell NR: Preliminary investigations of arteritic lesions using fluorescent-antibody technique . Br J Dermatol 77:211-220, 1965.Crossref 27. Paronetto F: Systemic nonsupparative necrotizing angiitis , in Miescher PA, Muller-Eberhard HJ (eds): Textbook of Immunopathology . New York, Grune & Stratton Inc, 1969, vol 2, pp 722-732. 28. Schroeter AL, Copeman PWM, Jordon RE, et al: Immunofluorescence of cutaneous vasculitis associated with systemic disease . Arch Dermatol 104:254-259, 1971.Crossref 29. Rogers PW, Bunn SM Jr, Kurtzman NA, et al: Schönlein-Henoch syndrome associated with exposure to cold . Arch Intern Med 128:782-786, 1971.Crossref 30. Sharan G, Anand RK, Sinha KP: Schönlein-Henoch syndrome after insect bite . Br Med J 1:656, 1966.Crossref 31. Cochrane CG, Hawkins D: Studies on circulating immune complexes: III. Factors governing the ability of circulating complexes to localize in blood vessels . J Exp Med 127:137, 1968.Crossref 32. Lazarus GS, Brown RS, Daniels JR, et al: Human granulocyte collagenase . Science 159:1483, 1968.Crossref 33. Cochrane CG: Studies on the localization of antigen-antibody complexes and other macromolecules in vessels: I. Structural studies . J Exp Med 118:489, 1963.Crossref 34. Cochrane CG: Studies on the localization of antigen-antibody complexes and other macromolecules in vessels: II. Pathogenetic and pharmacodynamic studies . J Exp Med 118:503, 1963.Crossref 35. Cochrane CG: Mechanisms involved in the deposition of immune complexes in tissues . J Exp Med 134:75-89, 1971.Crossref 36. Kurban AK, Ryan TJ: Fibrinogen titre, fibrinolysis, and platelet stickiness correlated with capillary bleeding or block in the skin . Trans St. John's Hosp Derm Soc 55:218, 1969. 37. Vaithaininathau T, Takats G: Cutaneous vasculitis and blood fibrinolysis . Lancet 2:108, 1968.Crossref 38. Cunliffe WJ: An association between cutaneous vasculitis and decreased blood fibrinolytic activity . Lancet 1:1226, 1968.Crossref 39. Cunliffe WJ, Dodman B, Holmes RL, et al: Local fibrinolytic activity in patients with cutaneous vasculitis . Br J Dermatol 84:99, 1971.Crossref 40. Dodman B, Cunliffe WJ, Roberts BE: Observations on tissue fibrinolytic activity in patients with vasculitis . Br J Dermatol 88:231-235, 1973.Crossref 41. Goecke DJ, Hsu K, Morgan C, et al: Vasculitis in association with Australian antigen . J Exp Med 134:330-336, 1971. 42. Parish WE, Rhodes EL: Bacterial antigens and aggregated gamma globulin in the lesions of nodular vasculitis . Br J Dermatol 79:131-147, 1967.Crossref 43. Parish WE: Studies on vasculitis: II. Some properties of complexes formed of antibacterial antibodies from persons with or without cutaneous vasculitis . Clin Allergy 1:111-121, 1971.Crossref 44. Parish WE: Studies on vasculitis: III. Decreased formation of antibody to M protein, group A polysaccharide and to some extotoxins in persons with cutaneous vasculitis after streptococcal infection . Clin Allergy 1:295-309, 1971.Crossref 45. Parish WE: Studies on vasculitis: IV. The low incidence of antibacterial anaphylactic antibodies in the sera of persons with cutaneous vasculitis following bacterial infection . Clin Allergy 1:433-446, 1971.Crossref 46. Barnett EV, Bluestone R, Cracchiolo A, et al: Cryoglobulinemia and disease . Ann Intern Med 73:95-107, 1970.Crossref 47. Meltzer M, Franklin EC, Elias K, et al: Cryoglobulinemia—A clinical and laboratory study: Cryoglobulins with rheumatoid factor activity . Am J Med 48:837-856, 1966.Crossref 48. Cochrane CG, Weigle WO, Dixon FJ: The role of polymorphonuclear leukocytes in the initiation and cessation of the Arthus vasculitis . J Exp Med 110:481-494, 1959.Crossref 49. Cream JJ, Bryceson AD, Ryder G: Disappearance of immunoglobulin and complement from the Arthus reaction and its relevance to studies of vasculitis in man . Br J Dermatol 84:106-109, 1971.Crossref 50. Lemmel E, Hurd ER, Ziff M: Differential effects of 6-mercaptopurine and cyclophosphamide on autoimmune phenomena in NZB mice . Clin Exp Immunol 8:355-362, 1971. 51. Steinberg AD, Kaltreider HB, Staples PJ, et al: Cyclophosphamide in lupus nephritis: A controlled trial . Ann Intern Med 75:165-171, 1971.Crossref

Fahs, Ivan J.;Lynch, Francis W.;Ward, Richard D.;Larson, Janice M.

1976 Archives of Dermatology

doi: 10.1001/archderm.1976.01630260047012

Abstract • From 1968 to 1973, the number of dermatologists in the United States per 100,000 population gradually increased from 1.6 to 1.8, with the West and Northeast regions showing relatively higher rates and the South and North Central regions showing relatively lower rates. The variation in rate, considered by geographic divisions, can be analyzed to identify areas in the United States that may be in need of additional dermatologists. Given the current number of dermatologists being certified by the American Board of Dermatology and given the current death rate, there appear to be a sufficient number of dermatologists to ensure future growth. (Arch Dermatol 112:235-242, 1976) References 1. Fahs IJ, Lynch FW: Dermatologists in the United States: I. A Study of Health Manpower Resources 1963-1970 . Portland, Ore, Division of Education and Communication and Division of Medical Services, National Program for Dermatology, 1970. 2. Fahs IJ, Lynch FW: Dermatologists in the United States: A study of health manpower resources, 1963 through 1970 . Arch Dermatol 105:836-844, 1972.Crossref 3. Haug JN, Roback GA: Distribution of Physicians, Hospitals, and Hospital Beds in the U.S., 1968: Regional, State, County, Metropolitan Areas . Chicago, American Medical Association, 1970, pp 1-337. 4. Haug JN, Roback GA: Distribution of Physicians, Hospitals, and Hospitals Beds in the U.S., 1969: Regional, State, County . Chicago, American Medical Association, 1970, vol 1, pp 1-291. 5. Haug JN, Roback GA: Distribution of Physicians, Hospitals, and Hospital Beds in the U.S., 1969: Metropolitan Areas . Chicago, American Medical Association, 1970, vol 2, pp 1-337. 6. Haug JN, Roback GA, Martin BC: Distribution of Physicians in the U.S., 1970: Regional, State, County, Metropolitan Areas . Chicago, American Medical Association, 1971, pp 1-329. 7. Roback GA: Distribution of Physicians in the U.S., 1971: Regional, State, County, Metropolitan Areas . Chicago, American Medical Association, 1972, pp 1-335. 8. Roback GA: Distribution of Physicians in the U.S., 1972: Regional, State, County . Chicago, American Medical Association, 1973, vol 1, pp 1-307. 9. Roback GA: Distribution of Physicians in the U.S., 1972: Metropolitan Areas . Chicago, American Medical Association, 1973, vol 2, pp 1-335. 10. Roback GA: Distribution of Physicians in the U.S., 1973: Regional, State, County, Metropolitan Areas . Chicago, American Medical Association, 1974, pp 1-353. 11. Tracy R (ed): Directory of Approved Internships and Residencies, 1969-1970 . Chicago, American Medical Association, 1969, pp 8-9. 12. Tracy R (ed): Directory of Approved Internships and Residencies, 1971-1972 . Chicago, American Medical Association, 1971, pp 5-6. 13. Tracy R (ed): Directory of Approved Internships and Residencies, 1972-1973 . Chicago, American Medical Association, 1972, pp 6-7. 14. Tracy R (ed): Directory of Approved Internships and Residencies, 1973-1974 . Chicago, American Medical Association, 1973, p 9. 15. Tracy R (ed): Directory of Approved Residencies, 1974-1975 . Chicago, American Medical Association, 1974, p 9. 16. Lerner W (ed): Statistical Abstract of the United States . US Dept of Commerce, Social and Economic Statistics Administration, Bureau of the Census, 1973, pp 13-16. 17. Population estimates and projections , in Current Population Reports , series P-25, publication 520. US Dept of Commerce, Bureau of the Census, (July) 1974. 18. Population estimates and projections , in Current Population Reports , series P-25, publication 518. US Dept of Commerce, Bureau of the Census, (June) 1974. 19. Fahs IJ, Lynch FW, Ravits HG: National Program for Dermatology, Placement Bureau Data 1973 . Evanston, Ill, National Program for Dermatology, American Academy of Dermatology, 1973. 20. Fahs IJ, Lynch FW, Ravits HG: National Program for Dermatology, Placement Bureau Data 1973 . Evanston, Ill, National Program for Dermatology, American Academy of Dermatology, 1973.

1976 Archives of Dermatology

doi: 10.1001/archderm.1976.01630260055013

Abstract Longest Executive Session Held At 34th Annual Meeting of Academy The membership of the American Academy of Dermatology took part in the longest executive session ever held at the 34th annual meeting in San Francisco.For a good part of the morning, the members discussed and acted upon proposed amendments to the AAD Bylaws. The changes in the Bylaws are published in the Bulletin of the American Academy of Dermatology.Rudolf L. Baer, M.D., who retired as President, said that the longer-than-usual session was scheduled to allow time for everyone to be heard when the amendments were discussed.He said that, although most of the California amendments were not passed by the necessary two-thirds majority, the discussion focused the attention of the rank-and-file membership on important constitutional issues. Five New Directors Elected During the executive session, members elected five physicians to the Board of Directors of the academy.Chosen to

King, Lloyd E.

1976 Archives of Dermatology

doi: 10.1001/archderm.1976.01630260059014

Abstract Pterygium Inversum Unguis. Presented by Lynn Drake, MD. A 31-year-old woman first noticed an abnormal fingernail growth pattern on the third and fourth digits of her right hand 18 months prior to consultation. Subsequently, the same digits on the left hand became involved, and now the fifth digits of both hands are becoming affected (Fig 1). There is no pain, unless she attempts to clip or file the nails. The fingernail growth rate appears to be normal, and the toenails are not involved. The hyponychium of the involved digits appears to be more adherent to the ventral surface of the nail plate than is normal, and the nail grooves are absent distally. Fungal cultures were negative. Discussion Dr T. B. Goodman: Since the report in the Archives of Dermatology (108:817, 1973), I have found two asymptomatic cases in women, both of whom were unaware of the nature or onset of References 1. Davies-Colley N: Disseminated clavus of the hands and feet . Trans Pathol Soc 30:451-453, 1879. 2. Scott MJ, Costello MJ, Simuangco S: Keratosis punctata palmaris et plantaris . Arch Dermatol Syphilol 64:301-308, 1951.Crossref 3. Buchanan RN: Keratosis punctata palmaris et plantaris . Arch Dermatol 88:644-650, 1963.Crossref 4. Brown FC: Punctate keratoderma . Arch Dermatol 104:682-683, 1971.Crossref

Laugier, Paul

1976 Archives of Dermatology

doi: 10.1001/archderm.1976.01630260061016pmid: 962357

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract To the Editor.— A case of secondary syphilis and sarcoidosis, which was diagnosed radiologically, was reported recently by McMillan and Burns (Arch Dermatol 111:264, 1975). We would like to report a similar case.The patient, born in 1932, was seen in the clinic of the Department of Ophthalmology, University of Geneva, in February 1971 for uveitis. One year before coming to the clinic, he had had a chancre of the foreskin and urethritis; he was unable to specify the treatment given at that time. Approximately six months later, spreading, erythematous lesions appeared on the torso. When he came to the clinic of the Department of Dermatology in July 1971, acuminate, papular lesions, scattered all over the torso, and epitrochlear nodes had been developing for three months. The following laboratory tests for syphilis were reactive: Bordet-Wassermann, + + +; Reiter protein complement fixation, + + +; VDRL test for syphilis (initially with a titer of 1/8; later,

Lee, Soon-Seng;Rapp, Yehoshua

1976 Archives of Dermatology

doi: 10.1001/archderm.1976.01630260061015

Abstract To the Editor.— Much effort has been channeled recently into the production of topical steroid preparations with increased percutaneous penetrative capability.While a rapid release of the steroid from its vehicle is certainly useful, we believe that rapid and increased penetration of the steroid into the dermis may not be entirely desirable. This is because the site of the anti-inflammatory action of the topically applied steroid is as yet unknown.The dermal vasoconstriction resulting from topical application of a steroid preparation is generally believed to reflect its effectiveness. However, occasional discrepancies between vasoconstriction bioassay results and clinical effectiveness do exist; correlation of vasoconstriction and clinical potency has been questioned by some.1 This suggests that, in some instances, dermal activity of the steroid does not correlate with effectiveness.The ointment base, because of its occlusive nature, allows a greater penetration by the topically applied steroid. The steroid ointment is generally References 1. Zaun H: Ist der Vasoconstrictionstest zum Vergleich der Wirkungsstärke örtlich applizierter Corticosteroide geeignet? Eine experimentelle Studie . Arch Klin Exp Derm 226:359-368, 1966.Crossref 2. Stoughton RB: Bioassay system for formulations of topically applied glucocorticosteroids . Arch Dermatol 106:825-827, 1972.Crossref 3. Frichot BC III, Zelickson AS: Steroids, lysosomes and dermatitis . Acta Derm Venereol 52:311-319, 1972. 4. Kaidbey KH, Kligman AM: Assay of topical corticosteroids by suppression of experimental inflammation in humans . J Invest Dermatol 63:292-297, 1974.Crossref

Leadbetter, Guy W.;DeCenzo, J. Michael

1976 Archives of Dermatology

doi: 10.1001/archderm.1976.01630260061017

Abstract To the Editor.— Recently, a 66-year-old man noted the onset of gross hematuria during an acute episode of erythema multiforme. Characteristic vesicobullous lesions were present on all body surfaces, including the glans penis near the urethral meatus. Urine culture grew Escherichia coli.Infection and malignancy are among the mechanisms thought to trigger erythema multiforme.1,2 Both conditions not only may stimulate an acute attack but also may produce hematuria. In addition, erythema multiforme per se may result in hematuria via involvement of the bladder, urethra, or kidneys.1,3,4Urologic consultation was obtained in this case. Intravenous pyelography showed a filling defect on the left wall of the bladder. A 2-cm grade 2, stage A, transitional-cell bladder cancer was cystoscopically resected. No vesicobullous lesions were seen in the lower part of the urinary tract.Our purpose in this communication is to emphasize that a urologic workup is imperative for patients with References 1. Champion RH: Erythema multiforme , in Rook A, Wilkinson DS, Ebling FJG (eds): Textbook of Dermatology . Philadelphia, FA Davis Co, 1968, pp 401-402. 2. Shelley WB: Consultations in Dermatology . Philadelphia, WB Saunders Co, 1972, pp 232-233. 3. Comaish JS, Kerr DNS: Erythema multiforme and nephritis . Br Med J 2:84-86, 1961.Crossref 4. Allen AC: Vesicular dermatoses , in Allen AC (ed): The Skin , ed 2. New York, Grune & Stratton Inc, 1967, pp 315-316. 5. DeCenzo JM, Morrisseau PM, Marocco G: Osler-Weber-Rendu syndrome: Urologist's view . Urology 5:549-553.Crossref

Goldman, Leon

1976 Archives of Dermatology

doi: 10.1001/archderm.1976.01630260062018

Abstract To the Editor.— In some areas of the body where transillumination can be done, point transillumination aids in the diagnosis of basal cell carcinoma. The invasive tumor cords make for better transmission of light.Because of the sebaceous gland structures of the nose, the differential diagnosis of skin lesions near the tip is often difficult. In our experience, this is the area of the highest failure rate of differential diagnosis. Cysts, fibromas, inflammatory nodules, deep dermal nevi, and sarcoids are some of the lesions considered in the differential diagnosis. Yet, this is one of the so-called vital facial zones where an early diagnosis, especially of sclerosing basal cell carcinoma, must be made.Transillumination1 is a technique that may help in this area before the biopsy is done. The optical characteristics of the skin are changed by cords of basal cells infiltrating the dermis. These cords make for better transmission References 1. Goldman L, Kitzmiller KW: Transillumination for the diagnosis of mucinous pseudocysts of the finger . Arch Dermatol 199:576, 1974.Crossref

Simmonds, Wayne L.

1976 Archives of Dermatology

doi: 10.1001/archderm.1976.01630260062019

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract To the Editor.— Harold C Fishman, MD, reported a case of acute, eruptive Darier disease in an adult (111:221-222, 1975).On Dec 4,1974, a fair-complexioned white man, age 57, was seen with a similar eruption of acute onset. He had received no previous treatment and was undiagnosed.He failed to respond to triamcinolone acetonide lotion or fluocinolone acetonide (Fluonid) solution. On Jan 16, 1975, he was given 15 mg/day of prednisolone, and tetracycline hydrochloride, 750 mg/day, for one week in addition to local steroid drugs without any change in his condition. Paul Hirsch, MD, confirmed the biopsy diagnosis as Darier disease.On Jan 31, 1975, all steroids were discontinued and the patient was given 100,000 units of vitamin A (Aquasol A) intramuscularly, and started therapy with 500,000 units of orally administered vitamin A. In one week, the pruritus had ceased and all lesions were regressing.On Feb 15, 1975, the

Odom, Richard B.

1976 Archives of Dermatology

doi: 10.1001/archderm.1976.01630260063021

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract This book contains 773 color photographs of clinical conditions and histological sections and approximately 70,000 words of text. In addition, Dr Leider presents a brief section on the elements of dermatology, and Dr Shapiro outlines a few basic principles of the microscopical anatomy of the skin. The authors divided their subjects into 20 sections on related conditions, based on etiological, morphological, pathogenetic, and developmental similarities. I was particularly impressed by the format the authors used to present their material. Each clinical condition portrayed is allotted a brief, concise, and precise paragraph of accompanying text; many of these paragraphs are supplemented with excellent histopathological photomicrographs and descriptions. Combining the three features of clinical photography, text, and histopathological material affords the reader a good deal more basic knowledge for further in-depth investigation. The clinical spectrum covered in this book is vast, including extensive representation of common conditions and reasonable inclusion of rare

Hollander, Alfred

1976 Archives of Dermatology

doi: 10.1001/archderm.1976.01630260063020

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract Petres and Hundeiker of the dermatologic university clinics of Freiburg and Giessen, respectively, cooperated in writing a monograph entitled Corrective Dermatology: Operations on the Skin. Their teacher, Kalkoff, director of the Dermatologic Unversity Clinic of Freiburg, points out in the preface that corrective dermatology has had a firm place in dermatology since the end of the last century. Lang of Vienna was famous for his plastic surgical operations on lupus vulgaris. More recently, Schreuss of Düsseldorf and Moncorps of Munich taught and practiced operative methods of corrective dermatology. The text describes various procedures in the treatment of numerous skin lesions, in particular, benign and malignant tumors. Discussed in detail are the bases of dermatosurgery, the necessary set of operative instruments, pre- and postoperative care, methods of inducing anesthesia, and techniques of incision and suturing. Dermabrasion, electrosurgery, and curettage are also mentioned. The authors have not had experience with Mohs chemosurgery

1976 Archives of Dermatology

doi: 10.1001/archderm.1976.01630260063022

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract Contrary to the promise of the title, this text is essentially a brief onceover of clinical dermatology in general—there are some 300 clinical entities discussed. Many discussions— familial angioedema, molluscum contagiosum, cutaneous leishmaniasis, sarcoidosis—bear no particular relevance to skin disease as it affects the elderly. Other subjects of particular pertinence to the elderly patient, such as actinic degeneration of the skin, precarcinomatous conditions, bullous pemphigoid, Kaposi sarcoma, psychological factors in skin disease, and mouth lesions due to dentures, deserve more exposition than they are accorded. The chapters on ulcers, itching, eczema, psoriasis, and systemic effects of skin disease are interesting, but contain little beyond the discussions available in standard dermatology reference texts. The author does suggest 200 mg of oral zinc sulfate three times daily to reduce the healing time of indolent leg ulcers. Such personal prescriptions and observations quicken the spirit of any text, but too few are included

1976 Archives of Dermatology

doi: 10.1001/archderm.1976.01630260064023

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract Dr Wilton M. Fisher: In Memoriam.— On Sept 17, 1975, Dr Wilton M. Fisher died after a protracted illness. Dr Fisher had a longand distinguished career in the Public Health Service. However, his importance to dermatology relates to his position as executive secretary of a National Institutes of Health general medical study section between 1963 and 1973. During this time, he contributed immensely to the advancement of investigative dermatology through this granting agency. He will be missed greatly by all of us who had the opportunity of knowing him.—Ed. Immunofluorescence Testing List.— The Task Force on Immunodermatology of the National Program for Dermatology is attempting to compile a complete list of the laboratories doing direct and indirect immunofluorescence testing either for their own institution only or on a commercial basis. This will facilitate the dissemination of information that may be of interest to individuals working in the field. It would