Archives of Dermatology and Syphilology

JAMIESON, ROBERT C.;McCREA, ADELIA

1937 Archives of Dermatology and Syphilology

doi: 10.1001/archderm.1937.01470200003001

Abstract After attempts made by us1 several years ago to determine the source of recurrences of ringworm, it was decided to investigate the possibility of shoes acting as a residual source of infection. It is unfortunate that at this time only a preliminary report can be given, but we hope to increase the series to at least one hundred cases in the near future and to publish a complete report at that time. Although fungous infections of the feet are common at present and widely disseminated, in the past most of our efforts toward eradication of the disease have dealt with the individual patient. A number of articles, however, have been written on sterilization of shoes and clothing and prevention of spread in such places as showers and locker rooms, among which may be listed the papers of Ayres, Anderson and Youngblood,2 Williams,3 Henderson,4 Osborne and Hitchcock References 1. Jamieson, R. C., and McCrea, A.: Recurrence or Reinfection in Ringworm of the Hands and Feet , Arch. Dermat. & Syph. 25:321 ( (Feb.) ) 1932. 2. Ayres, S., Jr.; Anderson, N. P., and Youngblood, E. M.: Fumigation as an Aid in the Control of Superficial Fungus Infection , Arch. Dermat. & Syph. 24:283 ( (Aug.) ) 1931. 3. Williams, C. M.: Tinea of the Nails as a Source of Reinfection of Tinea of the Feet , Arch. Dermat. & Syph. 18:730 ( (Nov.) ) 1928. 4. Henderson, Y.: Fungus Infection of the Feet: Fumigation of Shoes with Formaldehyde as a Means of Treatment , Arch. Dermat. & Syph. 26:710 ( (Oct.) ) 1932. 5. Osborne, E. D., and Hitchcock, B. S.: The Prophylaxis of Ringworm of the Feet , J. A. M. A. 97:453 ( (Aug. 15) ) 1931. 6. Shaffer, L. W.: Incidence and Prophylaxis of Epidermophytosis in School Children , J. Michigan M. Soc. 32:648, 1933 7. Factors Affecting the Immunity Balance in Dermatophytosis , Shaffer J. Michigan M. Soc. 34:601, 1935. 8. Cornbleet, T.: Disorders of the Feet as a Cause of Resistant Eczematoid Ringworm: Their Influence on the Amount of Sweating of the Feet , Arch. Dermat. & Syph. 29:887 ( (June) ) 1934. 9. In one of these cases scrapings were obtained from one old shoe and from one new one. The scrapings from the old shoe revealed Trichophyton in culture. Those from the new shoe remained sterile throughout. 10. Two of the shoes from which scrapings were obtained had been sterilized by formaldehyde fumigation.

McCARTHY, LEE;HUNTER, OSCAR B.

1937 Archives of Dermatology and Syphilology

doi: 10.1001/archderm.1937.01470200011002

Abstract The belief that there exists a relationship between acne vulgaris and an altered function of the endocrine glands has been expressed so often and for so long that it hardly seems necessary to repeat details here. However, a few salient factors in this regard should be mentioned. Although the relationship is not definitely proved, most modern writers do not hesitate to state without reservations that acne vulgaris is due to a dysfunction of the endocrine glands. References 1. Bloch, Bruno: Metabolism, Endocrine Glands and Skin-Diseases, with Special Reference to Acne Vulgaris and Xanthoma , Brit. J. Dermat. 43:61 ( (Feb.) ) 1931.Crossref 2. Stein, R. O.: Poisoning of the Skin as a Cause of Dermatosis in Puberty , Internat. Cong. Dermat. , 1935, p. 38. 3. Hollander, Lester: The Rôle of the Endocrine Glands in the Etiology and Treatment of Acne , Arch. Dermat. & Syph. 3:593 ( (May) ) 1921. 4. Lawrence, Charles H.: The Anterior Pituitary-Like Hormone: A Clinical Study of Its Effects in Acne Vulgaris , J. A. M. A. 106:983 ( (March 21) ) 1936. 5. Lawrence, C. H., and Feigenbaum, Jacob: The Treatment of Acne Vulgaris with Pregnancy Urine Extract , New England J. Med. 212:1213 ( (June 27) ) 1935. 6. Van Studdiford, M. T.: Effect of the Hormones of the Sex Glands on Acne , Arch. Dermat. & Syph. 31:333 ( (March) ) 1935. 7. Frank, R. T., and Goldberger, M. A.: Demonstration of the Female Sex Hormone in Human Blood , J. A. M. A. 87:1719 ( (Nov. 20) ) 1926. 8. Rosenthal, Theodore, and Kurzrok, Raphael: Excretion of Estrin in Acne , Proc. Soc. Exper. Biol. & Med. 30:1150 ( (May) ) 1933. 9. Neustaedter, in Mazer and Goldstein.10 10. Mazer, Charles, and Goldstein, Leopold: Clinical Endocrinology of the Female , Philadelphia, W. B. Saunders Company, 1932. 11. The preparation used was antuitrin S.

MUIR, KATHLEEN B.

1937 Archives of Dermatology and Syphilology

doi: 10.1001/archderm.1937.01470200026003

Abstract Eczematous weeping eruptions and vesicular or bullous eruptions are uncommon forms of dermatitis due to the administration of arsenical compounds.1 The more usual eruptions are the zoster-like eruptions, those resembling lichen ruber planus, those of erythema multiforme type, the fixed exanthems due to arsphenamine and the well known exfoliative dermatitides. The vesicular and bullous lesions of this unusual type of arsenical dermatitis often terminate in pyoderma. This complication usually comes on during the apparent healing of the eruption and is rarely seen in bullous eruptions except when they are due to arsenic.2 References 1. Kerl, W.: Schädigungen durch Salvarsan , in Jadassohn, J.: Handbuch der Haut- und Geschlechtskrankheiten , Berlin, Julius Springer, 1928, vol. 18, p. 615. 2. Kolle, W., and Zieler, K.: Handbuch der Salvarsantherapie , Berlin, Urban & Schwarzenberg, 1925, vol. 2, p. 141. 3. Brooke, H. G.: The Action of Arsenic on the Skin , Brit. M. J. 2:860 ( (Sept. 28) ) 1901. 4. Report of the Royal Medical and Chirurgical Society , Brit. M. J. 1:87 ( (Jan. 12) ) 1901.Crossref 5. Klauder, J. V.: The Clinical Aspects of Cutaneous Reactions After Arsphenamine , J. A. M. A. 82:933 ( (March 22) ) 1924.Crossref 6. Bauer, A. N.: Zur Kenntnis der Salvarsandermatosen , Dermat. Ztschr. 19:800, 1912.Crossref 7. Dreyfus, G. L.: Nebenwirkung des Silbersalvarsans , Deutsche med. Wchnschr. 45:1293 ( (Nov. 20) ) 1919.Crossref 8. Arndt: Salvarsanfragen , Med. Klin. 18:231 ( (Feb. 19) ) 1922. 9. Heyn, W.: Zur Frage der Salvarsandermatitis , Deutsche med. Wchnschr. 48:767 ( (June 9) ) 1922.Crossref 10. Birnbaum, G.: Neuere Untersuchungen über die Salvarsanschädigungen der Haut , Zentralbl. f. Haut- u. Geschlechtskr. 49:97, 1934. 11. Keim, H. L.: `` Erythema of the Ninth Day ," Arch. Dermat. & Syph. 31: 291 ( (March) ) 1935. 12. Tannenholz, H., and Muir, K. B.: Methods for Microchemical Demonstration of Arsenic in Tissues , Arch. Path. 15:789 ( (June) ) 1933. 13. Oppenheim, M., and Fantl, P.: Ueber Hauterkrankungen verursacht durch arsenhaltige Wandfarben: II. Versuche zum histologischen Nachweis von Arsenverbindungen in der Haut , Arch. f. Dermat. u. Syph. 170:488, 1934. 14. Sulzberger, Marion B., and Wise, Fred: The Contact or Patch Test in Dermatology , Arch. Dermat. & Syph. 23:519 ( (March) ) 1931. 15. Stokes, J. H., and Cathcart, E. P.: Contributing Factors in Postarsphenamine Dermatitis with Special Reference to the Influence of Focal and Intercurrent Infection , Arch. Dermat. & Syph. 7:14 ( (Jan.) ) 1923.

PREHN, D. T.

1937 Archives of Dermatology and Syphilology

doi: 10.1001/archderm.1937.01470200031004

Abstract A thorough review of the history of lymphogranuloma venereum is a study in itself. Hellerström's1 monograph published in 1929 is suggested as a good historical survey. The 933 references to this disease given by Stannus2 in 1933 afford an excellent bibliographic review. In this country DeWolf and Van Cleve3 and Sulzberger and Wise4 in 1932, Cole5 in 1933 and Burney6 in 1934 fully described the etiology, clinical course, pathology, differential diagnosis and past or present treatment of the disease. This article is presented to supply the available information gleaned from the clinical records, the individual study of some cases and the use of the specific antigen of Frei. Until recently the diagnosis of lymphogranuloma venereum was rarely made in the navy; in fact, the name was not included in the navy's nomenclature of diseases until 1934. Formerly this disease was incorrectly diagnosed as one References 1. Hellerström, S.: Acta dermat.-venereol. , (supp. 1) , 1929, p. 5. 2. Stannus, H. S.: A Sixth Venereal Disease , London, Baillière, Tindall & Cox, 1933. 3. DeWolf, H. F., and Van Cleve, J. V.: Lymphogranuloma Inguinale , J. A. M. A. 99:1065 ( (Sept. 24) ) 1932.Crossref 4. Sulzberger, M. R., and Wise, F.: Lymphopathia Venereum (Lymphogranulomatosis Inguinalis of Nicolas, Favre and Durand) , J. A. M. A. 99:1407 ( (Oct. 22) ) 1932.Crossref 5. Cole, H. N.: Lymphogranuloma Inguinale: Fourth Venereal Disease; Its Relation to Stricture of the Rectum , J. A. M. A. 101:1069 ( (Sept. 30) ) 1933.Crossref 6. Burney, L. E.: Ven. Dis. Inform. 15:1 ( (July) ) 1934. 7. Frei, Wilhelm: Klin. Wchnschr. 4:2148 ( (Nov. 5) ) 1925.Crossref 8. Wilmoth, C. L.: South. M. J. 21:108 ( (Feb.) ) 1928.Crossref 9. Granuloma Inguinale and Lymphogranuloma Inguinale, Queries and Minor Notes , J. A. M. A. 102:560 ( (Feb. 17) ) 1934. 10. Thomas, T. A., and McCarthy, Earl R.: Treatment of Lymphogranuloma Inguinale with Bouillon Filtrate , J. A. M. A. 102:766 ( (March 10) ) 1934.Crossref 11. Tamura, J. T.: Cultivation of Virus of Lymphogranuloma Inguinale and Its Use in Therapeutic Inoculation: Preliminary Report , J. A. M. A. 103:408 ( (Aug. 11) ) 1934.Crossref 12. Gay-Prieto, J.: Dermat. Wchnschr. 95:1056 ( (July 16) ) 1932. 13. Gilje, L. E.: U. S. Nav. M. Bull. 34:1 ( (Jan.) ) 1936.

STERNBERG, THOMAS H.;PILLSBURY, DONALD M.

1937 Archives of Dermatology and Syphilology

doi: 10.1001/archderm.1937.01470200047005

Abstract The question of an increased susceptibility of the skin to infection in avitaminosis A has been the subject of much discussion. Frazier and Hu1 noted that pyogenic dermatosis occurred frequently as a late phenomenon in patients suffering from this deficiency. McCoy2 in studying vitamin A deficiency in young albino rats found that animals with this disorder exhibited a definitely lowered resistance to Trichinella spiralis administered orally. Furthermore, in the rats with vitamin A deficiency any immunity to a second inoculation failed to develop, whereas controls were rendered completely immune by one inoculation. Workman,3 Green and Mellanby,4 Boynton and Bradford5 and others have also noted that in rats with vitamin A deficiency there was a general lack of resistance to experimental infections in various body structures other than the skin. MacKay6 in a large clinical study attempted to determine the effect of prophylactic treatment with References 1. Frazier, C. N., and Hu, C.: Cutaneous Lesions Associated with a Deficiency in Vitamin A in Man , Arch. Int. Med. 48:507 ( (Sept.) ) 1931.Crossref 2. McCoy, O. R.: Effect of Vitamin A Deficiency of Rats on Resistance to Infection with Trichinella Spiralis , Am. J. Hyg. 20:169 ( (July) ) 1934. 3. Workman, C. H.: Immunologic Significance of Vitamins: Influence of the Lack of Vitamins on Resistance of Rat, Rabbit and Pigeon to Bacterial Infection , J. Infect. Dis. 32:255, 1923.Crossref 4. Green, H. N., and Mellanby, E.: Vitamin A as an Anti-Infective Agent , Brit. M. J. 2:691, 1928.Crossref 5. Boynton, L. C., and Bradford, W. L.: Effect of Vitamins A and D on Resistance to Infection , J. Nutrition 4:323, 1931. 6. MacKay, H. M. M.: Vitamin A Deficiency in Children: Vitamin A Requirement of Babies; Skin Lesions and Vitamin A Deficiency , Arch. Dis. Childhood 9:133 ( (June) ) 1934.Crossref 7. Loewenthal, L. J. A.: A New Cutaneous Manifestation in the Syndrome of Vitamin A Deficiency , Arch. Dermat. & Syph. 28:700 ( (Nov.) ) 1933. 8. Sweet, L. K., and K'ang, H. J.: Clinical and Anatomic Study of Avitaminosis A Among the Chinese , Am. J. Dis. Child. 50:699 ( (Sept.) ) 1935. 9. Wright, H. P.; Frost, J. B.; Puchel, F., and Lawrence, M. R.: Vitamin A and the Common Cold , Canad. M. A. J. 25:65, 1931. 10. Hess, A. F.: Diet, Nutrition and Infection , New England J. Med. 207: 637, 1932. 11. Clausen, S. W.: Influence of Nutrition upon Resistance to Infection . Physiol. Rev. 14:309 ( (July) ) 1934. 12. Steenbock, H.: Satisfactory Ration for Stock Rats , Science 58:449. 1923. 13. Steenbock, H., and Nelson, E. M.: Fat Soluble Vitamine: Light in Its Relation to Ophthalmia and Growth , J. Biol. Chem. 56:355, 1923. 14. Steenbock, H., and Gross, E. G.: Fat-Soluble Vitamine , J. Biol. Chem. 40:501, 1919.

BUTLER, MILTON G.

1937 Archives of Dermatology and Syphilology

doi: 10.1001/archderm.1937.01470200051006

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract The condition to be described resembles none described in the literature except the ``chlor-acne'' described by Prosser White. A preliminary report is made because of the fact that recently the use of the drugs under consideration was recommended for treatment of fungous infections in man. Twenty-one cases have been observed. In seventeen the disorder was severe enough to require treatment. The patients treated were all young white men. Most of them were aged from 19 to 23; one was 34. The chemicals which I later found to be causative were used in a mixture. The first acne-like eruption appeared one month after the products were manufactured in a powder form. All the men exhibiting the condition were employed in sacking the mixture. The disorder here described developed within the next six months after contact with the chemicals. I have seen four laboratory workers who had a milder, more localized reaction

BERNSTEIN, EUGENE TRAUGOTT

1937 Archives of Dermatology and Syphilology

doi: 10.1001/archderm.1937.01470200055007

Abstract Although lichen scrofulosorum is the oldest known tuberculous eruption, many phases of the clinical and pathologic conceptions of this disorder are still controversial. It is widely accepted that the cutaneous manifestation represents an expression of hematogenous dissemination of tubercle bacilli or their toxins during the so-called secondary stage described by Ranke.1 In agreement with this point of view are the many observations indicating the preponderance of cutaneous lesions in children, who, as a class, are most prone to bacillemia or toxemia of this type (tuberculosis of the lymph nodes). The problems presented in the evaluation of the data culled from the literature may be classified conveniently, for the purposes of this report, into three categories: clinical picture, histologic picture and internal medical aspects. 1. Clinical Picture. The morphologic attributes of lichen scrofulosorum may be imitated closely by a host of dermatoses, and the differential diagnosis may in References 1. Ranke, K. E.: Ausgewählte Schiften zur Tuberkulosepathologie , Berlin, Julius Springer, 1928. 2. Jadassohn, J.: Demonstration eines Falles von Lupus Erythematosus disseminatus (case of Tièche), Verhandl. d. deutsch. dermat. Gesellsch., 1906, p. 463. 3. Jacobi, E., in discussion on Wolf: Demonstration von drei Fällen von Lichen scrofulosorum, Verhandl. d. deutsch. dermat. Gesellsch., 1898, p. 486. 4. Lewandowsky, F.: Die Tuberkulose der Haut , Berlin, Julius Springer, 1916. 5. Volk, R., in Jadassohn, J.: Handbuch der Haut- und Geschlechtskrankheiten , Berlin, Julius Springer, 1931, vol. 10, part (1) , p. 331. 6. Klingmüller, V.: Beiträge zur Tuberkulose der Haut , Arch. f. Dermat. u. Syph. 69:167, 1904.Crossref 7. Nobl, G.: Zur Pathogenese des Lichen skrofulosorum , Dermat. Ztschr. 16:205, 1909.Crossref 8. Jadassohn, J.: Die Tuberculide , Arch. f. Dermat. u. Syph. 119:10, 1914.Crossref 9. Montgomery, D.: Coincidence of Lichen Scrofulosorum with Lupus Erythematosus , Arch. Dermat. & Syph. 31:371 ( (March) ) 1935. 10. Keil, H.: Coincidence of Lichen Scrofulosorum with Lupus Erythematosus , Arch. Dermat. & Syph. 31:872 ( (June) ) 1935. 11. Montgomery, D.: Reply , Arch. Dermat. & Syph. 31:873 ( (June) ) 1935. 12. Arch. Dermat. & Syph. 34:1049 [ (Dec.) ] 1936 13. Wallhauser, H. J. F.: Lichen Pilaris seu Spinulosus (Crocker) , Arch. Dermat. & Syph. 8:776 ( (Dec.) ) 1923. 14. Klingmüller.6 Nobl.7 15. Lesseliers: Contribution a l'étude du lichen scrophulosorum , Ann. de dermat. 7:897, 1906. 16. Lewandowsky, cited by Volk.5

MILLER, J. K.;O'DONNELL, H. J.

1937 Archives of Dermatology and Syphilology

doi: 10.1001/archderm.1937.01470200064008

Abstract Complete reports on the toxic effects of arsenical preparations in the treatment of syphilis have been made by the Medical Research Council,1 by Phelps and Washburn,2 by Kerl3 and by Cole and his co-workers.4 However, few cases have been recorded in which a reaction followed the use of tryparsamide. This may be due in part to the fact that tryparsamide is used infrequently except in treatment of paresis. The report of Cole and his co-workers includes a case of dermatitis and a case of severe gastro-intestinal reactions following the administration of tryparsamide. Robinson5 also reported a case of fixed dermatitis due to tryparsamide, the first mention in the literature. In a case of sensitivity to tryparsamide which we observed there were such severe disturbances that the occurrence was thought worthy of record. REPORT OF A CASE M. L. C., a man aged References 1. Report of the Salvarsan Committee, Medical Research Council, Special Report Series, nos. 61 to 70, London, His Majesty's Stationery Office, 1922, vol. 2, pp. 4-94. 2. Phelps, J. B., and Washburn, W. A.: Urol. & Cutan. Rev. 34:458-476, 1930. 3. Kerl, W.: Salvarsan Schädigungen , in Jadassohn, J.: Handbuch der Haut- und Geschlechtskrankheiten , Berlin, Julius Springer, 1928, vol. 18, p. 604. 4. Cole, H. N., and others: Toxic Effects Following the Use of the Arsphenamines , J. A. M. A. 97:897-904 ( (Sept. 26) ) 1931. 5. Robinson, H. M.: Fixed Dermatitis Due to Tryparsamide , Am. J. Syph. & Neurol. 17:507-509 ( (Oct.) ) 1933. 6. Wirz, F.: München. med. Wchnschr. 77:1225-1227 ( (July 18) ) 1930. 7. Sirota, L. S.: A Rare Manifestation of Sensitivity to Neoarsphenamine , Dermat. Ztschr. 68:198-200 ( (Jan.) ) 1934. 8. Moriyama, G.: Jap. J. Dermat. & Urol. 29:1045-1062, 1929. 9. Sulzberger, M.: Hypersensitiveness to Arsphenamine in Guinea-Pigs , Arch. Dermat. & Syph. 20:669-697 ( (Nov.) ) 1929.

HEDGE, HARRY M.

1937 Archives of Dermatology and Syphilology

doi: 10.1001/archderm.1937.01470200067009

Abstract As I have given hundreds of intramuscular injections of enesol in cases of lichen planus, it is interesting to record one case in which a typical nitritoid crisis followed the injection. Enesol is a French product, a combination of arsenic and mercury. The manufacturers state that it is a masked resultant chemical combination in which there is a molecule to molecule combination of oxymercuriosalicylic anhydride with mercury methylarsinate; for brevity, after its combination it is called salicylarsinate of mercury. The following claims are made on the basis of many hundreds of reports: ". . . we can also assert that enesol, as shown in published notes of cases, never gives rise either to a violent Herxheimer reaction or to the nitritoid crisis described by Milian,''1 and ". . . to cause death in an adult man weighing 65 Kg. we should have to inject 16¼ grains (1.05 Gm.) of enesol.''2 The drug References 1. Milian, G.: The Reaction of Herxheimer , Paris méd. 12:537-548 ( (Nov. 15) ) 1913. 2. Coignet: Note on New Soluble Injectable Salt of Mercury , Lyon méd. 102:1113-1123 ( (June 5) ) 1904.

LAYMON, CARL W.

1937 Archives of Dermatology and Syphilology

doi: 10.1001/archderm.1937.01470200069010

Abstract "Extracellular cholesterinosis'' was the term which Urbach used to designate a unique dermatosis which he studied in great detail in association with Epstein and Lorenz. The observations of these workers, including the results of metabolic and histochemical determinations, were published in several contributions in 1932 and 1933.1 The patient whose condition they investigated was first presented by Professor Kerl2 before the Vienna dermatologic society on Oct. 22, 1930, as exhibiting "multiple nodule formation containing much lipoid.'' In discussing the condition at that time Urbach maintained that the disease could be differentiated from xanthoma histologically although the two conditions were similar clinically. Kerl3 reported the case in greater detail in 1932. As far as can be ascertained, there have been no other reports concerning extracellular cholesterosis. For several years a patient with an extremely odd dermatosis was under the care of Dr. Henry Michelson; that patient References 1. Urbach, E.; Epstein, E., and Lorenz, K.: Beiträge zu einer physiologischen und pathologischen Chemie der Haut: Extrazellulare Cholesterinose , Arch. f. Dermat. u. Syph. 166:243-272, 1932.Crossref 2. Urbach, Erich: Lipoidstoffwechselerkrankungen der Haut , in Jadassohn, J.: Handbuch der Haut- und Geschlechtskrankheiten , Berlin, Julius Springer, 1932, vol. 12, pt. (2) , pp. 320-330 3. Kutane Lipoidosen, Dermat. Ztschr. 66:371-386, 1933.Crossref 4. Kerl: Multiple Knotenbildung, reichlich Lipoidenthaltend , Zentralbl. f. Haut- u. Geschlechtskr. 36:37, 1931. 5. Kerl, Wilhelm: Ueber eine neuartige generalisierte Lipoid-Infiltration mit vorwiegender, zum Teil knotenformiger Beteiligung der Haut und Schleimhaut , in Neisser, A., and Jacobi, E.: Ikonographia dermatologica , Berlin, Urban & Schwarzenberg, 1932. 6. Michelson, Henry E., and Laymon, Carl W.: Necrobiosis Lipoidica Diabeticorum , J. A. M. A. 103:163-169 ( (July 21) ) 1934.Crossref 7. Peters, J. P., and Van Slyke, D. D.: Quantitative Clinical Chemistry , ed. 1, Baltimore, Williams & Wilkins Company, 1931, p. 218. 8. Howell, W. H.: Textbook of Physiology , ed. 11, Philadelphia, W. B. Saunders Company, 1930, pp. 31 and 956. 9. Kutschera-Aichbergen, H.: Beitrag für Morphologie der Lipoide , Virchows Arch. f. path. Anat. 256:569, 1925.Crossref 10. Schaaf, F., and Werner, A. J.: Die Pathogenese der Xanthome , Arch. f. Dermat. u. Syph. 162:217-239, 1930.Crossref 11. Wile, U. J.; Eckstein, H. C., and Curtiss, A. C.: Lipid Studies in Xanthoma , Arch. Dermat. & Syph. 19:35-51 ( (Jan.) ) 1929. 12. Eckstein, H. C., and Wile, U. J.: Lipid Studies in Xanthoma , J. Biol. Chem. 87:311-317 ( (June) ) 1930. 13. Heuck, cited by Balbi, E.: Ricerche intorno alla patogenesi della necrobiosis lipoidica diabeticorum Urbach-Oppenheim , Gior. ital. di dermat. e sif. 74:14-43 ( (Feb.) ) 1933. 14. Kaufmann-Lehmann, cited by Balbi, E.: Ricerche intorno alla patogenesi della necrobiosis lipoidica diabeticorum Urbach-Oppenheim , Gior. ital. di dermat. e sif. 74:14-43 ( (Feb.) ) 1933.

Bregman, Alexander

1937 Archives of Dermatology and Syphilology

doi: 10.1001/archderm.1937.01470200085011

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract A case of alopecia areata in which the lesions were artificially produced by intravenous injections of quinine hydrochloride and ethyl carbamate (urethane) is reported. The injections were given for obliteration of varicose veins, and the discovery of lesions of alopecia areata was accidental. In my opinion this case points to the sympatheticotonic origin of alopecia areata. REPORT OF A CASE Mrs. E. B., aged 32, had one child. The family and the past personal history were irrelevant. The patient had never had any disorder of the skin or scalp, and the general physical and laboratory examinations gave negative results. In May 1934 the patient was given an injection of 2 cc. of quinine hydrochloride and ethyl carbamate to obliterate a varicosity on the right leg. No further injections were given. In May 1936 she returned with another small varicosity on another part of the right leg. She was again given

Kelley, Eugene F.

1937 Archives of Dermatology and Syphilology

doi: 10.1001/archderm.1937.01470200086012

Abstract Reports of eruptions accompanied by keratosis of the palms and soles caused by retention of arsenic, as proved by clinical observation and by the presence of arsenic in the urine, the blood and the skin and its appendages, are not uncommon in the dermatologic literature. The lesions are more or less similar clinically, consisting of thickening of the horny layer in the form of discrete plugs, plaques or diffuse involvement, and vary in thickness. The occurrence of exfoliation en masse in the form of complete casts of the hands, with arsenic as a causative factor, is rare, and the reporting of the following case is, I believe, justified. REPORT OF CASE An American-born housewife aged 33 presented herself at the dermatologic clinic of the Yonkers General Hospital on Sept. 28, 1935, complaining of a ``loosening of the outer skin of both hands, which began five days before as dryness References 1. The specimens were presented at the meeting of the New York Academy of Medicine, Section of Dermatology and Syphilis, on Oct. 1 , 1935 2. Arch. Dermat. & Syph. 33:912 [ (May) ] 1936). 3. Ayres, S., Jr., and Anderson, N. P.: Cutaneous Manifestations of Arsenic Poisoning , Arch. Dermat. & Syph. 30:33 ( (July) ) 1934. 4. Cannon, A. B.: Chronic Arsenical Poisoning , New York State J. Med. 36:219, 1936. 5. Fordyce, J. A.; Rosen, I., and Myers, C. N.: Quantitative Studies in Syphilis , Am. J. Syph. 7:21 ( (April) ) 1923.

Montgomery, Douglass W.

1937 Archives of Dermatology and Syphilology

doi: 10.1001/archderm.1937.01470200090013

References 1. Adamson, quoted by Goldsmith, W. Noel: Recent Advances in Dermatology , Philadelphia, P. Blakiston's Son & Co., 1936, p. 416.

Baer, Harry Leonard

1937 Archives of Dermatology and Syphilology

doi: 10.1001/archderm.1937.01470200091014

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.

Myers, C. N.;Throne, Binford

1937 Archives of Dermatology and Syphilology

doi: 10.1001/archderm.1937.01470200092015

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract To the Editor.—In an interesting article in the August issue of the Archives entitled ``Tricophytin and Allergy to Tricophytin'' by Sulzberger, Lewis and Wise, the following paragraph is found: "Van Dyck, Kingsbury, Throne and Myers, working at about the same time, obtained remarkably effective therapeutic results through the employment of approximately the same method as that outlined by Sulzberger and Wise. These investigators made no mention of the regular reduction in cutaneous sensitivity to tests with tricophytin.'' For the basis of this statement Sulzberger and his co-workers referred to an article by Van Dyck, Kingsbury, Throne and Myers entitled "The Use of Tricophytin as a Diagnostic and Therapeutic Agent in Mycotic Infections of the Skin," which appeared in the New York State Journal of Medicine (31:611 [May 15] 1931). No mention, however, was made by Sulzberger and his co-workers of a second article on the same subject,

Sulzberger, Marion B.;Lewis, George;Wise, Fred

1937 Archives of Dermatology and Syphilology

doi: 10.1001/archderm.1937.01470200093016

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract To the Editor.—The letter of Drs. Myers and Throne was submitted to us for our comment. In our recent article in the Archives (34:207 [Aug.] 1936) we simply stated the fact that Van Dyck, Kingsbury, Throne and Myers in their original articles (New York State J. Med.31:611, 1931) did not mention regular cutaneous hyposensitization but discussed the therapeutic effects of injections of trichophytin. We further mentioned that Sulzberger and Wise reported that "repeated intracutaneous injections of trichophytin regularly [italics ours] succeed in reducing sensitivity of the skin to trichophytin.'' This statement is based on the report of successful reduction of cutaneous sensitivity in fifteen of eighteen cases as recorded in the paper by Sulzberger and Wise read before the Section of Dermatology and Syphilology of the American Medical Association at the meeting in Philadelphia, on June 10, 1931, and listed in the program of the

Belisario, J. C.

1937 Archives of Dermatology and Syphilology

doi: 10.1001/archderm.1937.01470200094017

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract To the Editor.—I wish to draw your attention to a conclusion drawn by the abstracter of my article entitled "The Treatment of Acne Vulgaris with Special Reference to X-Rays'' which appeared in the Medical Journal of Australia (2:656 [Nov. 9] 1935). He stated in the Archives (34:500 [Sept.] 1936) that I ascribed the good results I obtained to the fact that "standardization was checked by three dosimeters, and the cutaneous tolerance of most of the patients was tested before treatment was given." I ascribed the good results not to these factors but to the fact that I did not allow for the extra 20 per cent to 25 per cent of the dose due to secondary radiation which is to be taken into consideration when large areas like the face or the back are treated. Consequently in delivering eight weekly one-fourth erythema doses as measured by the

1937 Archives of Dermatology and Syphilology

doi: 10.1001/archderm.1937.01470200095018

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract THE AMERICAN BOARD OF DERMATOLOGY AND SYPHILOLOGY Notice is again given that written examinations for applicants of group B will be held in various cities throughout the United States on April 17, 1937. Applications must reach the secretary of the board no later than March 1,1937. Oral examinations for applicants of groups A and B will be held in Philadelphia on June 7 and 8, 1937. An application blank and a booklet of information may be obtained from the secretary of the board, Dr. C. Guy Lane, 416 Marlboro Street, Boston.

Knowles, Frank C.

1937 Archives of Dermatology and Syphilology

doi: 10.1001/archderm.1937.01470200096019

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.

Rattner, Herbert

1937 Archives of Dermatology and Syphilology

doi: 10.1001/archderm.1937.01470200097020

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.

Combes, Frank C.;Scheer, Max

1937 Archives of Dermatology and Syphilology

doi: 10.1001/archderm.1937.01470200107021

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract Pemphigus of the Eyes. Presented by Dr. A. Benson Cannon. Mrs. L. R., aged 72, Hungarian, is presented from the New York City Hospital. She has been blind for the past three years; the symptoms of sore mouth and weakness appeared only two years ago. Sixteen years ago the patient had hemiplegia, but she claims that except for that she has always been in good health. She has also undergone cholecystectomy and appendectomy. In both eyes there are adhesions of the lower lid to the eyeball and complete obliteration of the lower cul-de-sac. The eyeballs besides being adherent are completely shrunken. The mucous membranes of the mouth and lips, particularly on the roof of the mouth, show ruptured bullae. The Wassermann reaction was negative. Chemical examination of the blood showed 30 mg. of nonprotein nitrogen and 190 mg. of sugar per hundred cubic centimeters. The Pels-Macht test showed a

Nisbet, Thomas W.;Anderson, Nelson Paul

1937 Archives of Dermatology and Syphilology

doi: 10.1001/archderm.1937.01470200117022

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract Large-Spored Ringworm of the Scalp. Presented by Dr. Nelson Paul Anderson. N. D., a boy aged 8 years, has had this condition for five years. No other member of the family is affected. The patient was first seen at the Yale Street clinic in November 1932, and at that time the eruption was said to have been present for two or three years. There is widespread diffuse scaling in the scalp, and numerous small but scattered areas of atrophic alopecia are present. When the hair is clipped close one can see numerous small black dots. These apparently are small, broken-off hairs covered with a thin layer of skin. Histologic examination of removed hairs revealed numerous large spores of an endo-ectothrix type. Culture on Sabouraud's medium showed Trichophyton acuminatum. DISCUSSION Dr. C. R. Halloran: If a microscopic study revealed spores the disorder is tinea of the scalp. Clinically the condition

Nomland, Ruben;Wien, Max S.

1937 Archives of Dermatology and Syphilology

doi: 10.1001/archderm.1937.01470200125023

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract Parapsoriasis. Presented by Dr. A. W. Stillians. A Case for Diagnosis (Hemangioma Which Has Undergone Spontaneous Involution with Residual Nodules of Angiofibroma?). Presented by Dr. S. W. Becker and Dr. E. E. Stenhouse. This woman, aged 30, presents on the lower portion of the back a lesion which has been present since birth. It was said to be a vascular nevus, and so far as the patient knows it has not undergone any changes. There has been no ulceration, and no treatment has been administered. The personal and family history are unimportant except for the fact that the patient has always been frail and underweight. On the lower left portion of the back there is a bluish red atrophic plaque, approximately 5 by 10 cm.; it is irregular in outline and somewhat depressed and exhibits several nodules within its outer margins. The largest nodule is 3 cm. in diameter, erythematous,

Garner, Vaughn C.;Smith, Herbert J.

1937 Archives of Dermatology and Syphilology

doi: 10.1001/archderm.1937.01470200145024

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract Granulomatous Type of Bromoderma. Presented by Dr. William O. Roop, Atlantic City, N. J. R. K., a widow aged 55, about two months ago began taking a patent medicine for her "nerves"; soon after pustules developed on the face. The eruption grew steadily worse under the continuance of the medication. She then consulted a physician, who suspected syphilis and requested that a test of the blood be made. When I first saw the patient she presented several small discrete papulopustular lesions on the lower eyelids, and on her forehead and face close to the eyes there were a few granulomatous button-like lesions the size of a 25 cent piece, surfaces of which were somewhat crusted and studded with pustules. The Wassermann and the Kahn reaction of the blood were negative. The urinalysis showed bromine and a trace of albumin. The blood pressure was 110 systolic and 60 diastolic. DISCUSSION Dr.

Traub, Eugene F;Rulison, Ray H.

1937 Archives of Dermatology and Syphilology

doi: 10.1001/archderm.1937.01470200151025

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract Darier-Roussy Sarcoid. Presented by Dr. Howard Fox. J. N. C., a man aged 50, a physician, has suffered for nearly twenty years from an eruption in the center of his back. It consists of smooth, semisolid, more or less lumpy reddish elevations forming a palm-sized partial circle. As far as the patient is aware, the eruption on the back has never cleared up or changed materially since its onset. It has never caused any subjective symptoms. Three months before the outbreak of this eruption several similar patches appeared on the anterior aspect of the shoulder joints and in the clavicular region. The same tendency to form annular groups was noted. Examination of the blood showed 7,300 white cells; the differential cell count was normal. Histologic examination of a nodule excised from the back was reported by Dr. T. J. Riordan to show the Darier-Roussy type of sarcoid. The lesions on

Silver, Henry;Kelley, Eugene F.

1937 Archives of Dermatology and Syphilology

doi: 10.1001/archderm.1937.01470200164026

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract Adenoma Sebaceum. Presented by Dr. Samuel Feldman. J. M., an orphan boy aged 11 years, was admitted to the Morrisania Hospital because of fever and vomiting which had been present for four days and repeated attacks of convulsions. The diagnosis on admission was hydrocephalus, subarachnoid hemorrhages, convulsions and tuberous sclerosis. The boy was delivered with the aid of forceps; his head has always been large; he did not learn to walk till he was 4 years old. He never talked; his mentality is low, and he has had four or five attacks of convulsions every year. The skin of both cheeks and that of the chin and forehead are studded with numerous reddish, waxy and transparent nodules varying in size from that of a pinhead to that of a millet seed. On the left side of the trunk there are a number of yellowish flat elevated growths such as

1937 Archives of Dermatology and Syphilology

doi: 10.1001/archderm.1937.01470200171027

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract In the third volume of the nouvelle pratique dermatologique the first two hundred pages are devoted to the conclusion of the discussion of syphilis by Milian. The regional aspects of the tertiary manifestations are first described, and leukoplakia is then given extended consideration, as are the atrophic changes occurring in the skin as sequelae of syphilitic manifestations. The association of syphilis with other diseases, particularly tuberculosis and cancer, is then discussed. The changes in temperature in the various stages of syphilis are emphasized in a special chapter, the author pointing out that while syphilis is often regarded as an afebrile disease, the temperature is elevated at some time in the course in perhaps three fourths of the cases. After considering the biotropism of syphilis, Milian discusses the treatment of the disease. This section is short but bears throughout the imprint of the writer's great experience and original thought in this

1937 Archives of Dermatology and Syphilology

doi: 10.1001/archderm.1937.01470200172028

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract This is an excellent book in every way. It is compact, well written and copiously illustrated, its 150 pages containing 94 illustrations in black and white. After first describing the anatomy of, and pathologic changes in, the nails, Pardo-Castello considers diseases of the nails under four groups: diseases peculiar to the nails; onychodystrophies; ungual manifestations of dermatoses and of systemic diseases, and congenital diseases. There is a chapter devoted to the roentgen treatment of diseases of the nails; there are also a list of occupations in which diseases of the nails occur and one of ungual symptoms due to poisons. The Archives has on several occasions stressed the need for monographs such as this one. The work is practical and sound. The literature is brought up to date; when it is possible, treatment is suggested, and there is a full index. The book is a useful adjunct to the

1937 Archives of Dermatology and Syphilology

doi: 10.1001/archderm.1937.01470200172030

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.

1937 Archives of Dermatology and Syphilology

doi: 10.1001/archderm.1937.01470200172029

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables. Abstract This book is concerned solely with urology.

1937 Archives of Dermatology and Syphilology

doi: 10.1001/archderm.1937.01470200173031