RSC Advances

Rittidach, Tanawut; Sillapaprayoon, Siwapech; Chantho, Varissara; Pimtong, Wittaya; Charoenphandhu, Narattaphol; Thongbunchoo, Jirawan; Krishnamra, Nateetip; Bootchanont, Atipong; Porjai, Porramain; Pon-On, Weeraphat

doi: 10.1039/d3ra04555bpmid: 37859778

Bioceramic materials have a wide range of applications in the biomedical field, such as in the repair of bone defects and dental surgery. Silicate-based bioceramics have attracted biomedical researchers' interest due to their bioactivity and biodegradability. In this study, extended the scope of ZAS utilization in bone tissue engineering by introducing calcium–magnesium-silicate (diopside, CMS) as an interface material aim to develop a machinable bioceramic composite (ZASCMS) by the sol–gel method. The physicochemical characterization, in vitro biological properties and in vivo zebrafish cytotoxicity study of ZAS-based composites as a function of CMS contents, 0, 25, 50, 75 and 100 wt%, were performed. Results showed that the as-prepared ZASCMS possessed porous architecture with well-interconnected pore structure. Results also revealed that the mechanical properties of ZASCMS composite materials were gradually improved with increasing CMS contents. The ZASCMS composites with more than 50 wt% CMS had the highest compressive strength and modulus of 6.78 ± 0.62 MPa and 340.10 ± 16.81 MPa, respectively. Regarding in vitro bioactivities, the composite scaffolds were found to stimulate osteoblast-like UMR-106 cell adhesion, growth, and proliferation. The antibacterial activity of the ZASCMS composite scaffolds was tested against Staphylococcus epidermidis (S. epidermidis) and Escherichia coli (E. coli) also exhibited an antibacterial property. Furthermore, the in vivo studies using embryonic zebrafish were exposed to as-prepared particles (0–500 μg mL−1) and showed that the synthesized ZAS, CMS and ZASCMS composite particles were non-toxic based on the evaluation of survivability, hatching rate and embryonic morphology. In conclusions, our results indicated that the synthesized composite exhibited their biological properties and antibacterial activity, which could well be a promising material with high potential to be applied in orthopaedic and dental tissue engineering.

Sar, Pintu; Kundu, Sandip; Ghosh, Aniruddha; Saha, Bidyut

doi: 10.1039/d3ra05062apmid: 37859781

The treatment of environmental pollution by employing microorganisms is a promising technology, termed bioremediation, which has several advantages over the other established conventional remediation techniques. Consequently, there is an urgent inevitability to develop pragmatic techniques for bioremediation, accompanied by the potency of detoxifying soil environments completely. The bioremediation of contaminated soils has been shown to be an alternative that could be an economically viable way to restore polluted soil. The soil environments have long been extremely polluted by a number of contaminants, like agrochemicals, polyaromatic hydrocarbons, heavy metals, emerging pollutants, etc. In order to achieve a quick remediation overcoming several difficulties the utility of biosurfactants became an excellent advancement and that is why, nowadays, the biosurfactant mediated recovery of soil is a focus of interest to the researcher of the environmental science field specifically. This review provides an outline of the present scenario of soil bioremediation by employing a microbial biosurfactant. In addition to this, a brief account of the pollutants is highlighted along with how they contaminate the soil. Finally, we address the future outlook for bioremediation technologies that can be executed with a superior efficiency to restore a polluted area, even though its practical applicability has been cultivated tremendously over the few decades.

Xue, Liang-Mei; Li, Song-Bo; An, Sheng-Li; Li, Ning; Ma, Hui-Pu; Li, Meng-Xin

doi: 10.1039/d3ra04991dpmid: 37859775

This study aims to investigate the implications of transition-metal Zn doping at the B-site on the crystal structure, average thermal expansion coefficient (TEC), electrocatalytic activity, and electrochemical performance of LaBaFe2O5+δ by preparing LaBaFe2−xZnxO5+δ (x = 0, 0.05, 0.1, 0.15, 0.2, LBFZx). The X-ray diffraction (XRD) results show that Zn2+ doping does not change the crystal structure, the unit cell volume increases, and the lattice expands. The X-ray photoelectron spectroscopy (XPS) and mineral titration results show that the oxygen vacancy concentration and Fe4+ content gradually increase with the increase in doping amount. TEC decreases with the increase in Zn2+ doping amount, and the TEC of LBFZ0.2 is 11.4 × 10−6 K−1 at 30–750 °C. The conductivity has the best value of 103 S cm−1 at the doping amount of x = 0.1. The scanning electron microscopy (SEM) images demonstrate that the electrolyte CGO(Gd0.1Ce0.9O1.95) becomes denser after high-temperature calcination, and the cathode material is well attached to the electrolyte. The electrochemical impedance analysis shows that Zn2+ doping at the B-site can reduce the (Rp) polarization resistance, and the Rp value of the symmetric cell with LaBaFe1.8Zn0.2O5+δ as cathode at 800 °C is 0.014 Ω cm2. The peak power density (PPD) value of the anode-supported single cell is 453 mW cm−2, which shows excellent electrochemical performance.

Amano, Ken-ichi; Tozawa, Kentaro; Tomita, Maho; Takagi, Riko; Iwayasu, Rieko; Nakano, Hiroshi; Murata, Makoto; Abe, Yousuke; Utsunomiya, Toru; Sugimura, Hiroyuki; Ichii, Takashi

doi: 10.1039/d3ra04459apmid: 37859780

Interaction between two bodies in a liquid metal is an important topic for development of metallic products with high performance. We conducted atomic force microscopy measurements and achieved the interaction between the substrate and the probe in liquid Ga of an opaque and highly viscous liquid. The interaction cannot be accessed with the normal atomic force microscopy, electron microscopy, and beam reflectometry. We performed a theoretical calculation using statistical mechanics of simple liquids by mixing an experimentally derived quantum effect. From both experiment and theory, we found an unusual behaviour in the interaction between the solvophobic substances, which has never been reported in water and ionic liquids. Shapes of the interaction curves between several solvophobic and solvophilic pairs in liquid Ga are also studied.

Chaudhary, Simran; Kędziera, Dariusz; Rafiński, Zbigniew; Dobrzańska, Liliana

doi: 10.1039/d3ra05713epmid: 37859777

Polymorph screenings for two related dipodal N-donor ligands containing a biphenyl core, namely 4,4′-bis(pyridin-4-ylmethyl)-1,1′-biphenyl (1) and 4,4′-bis(1H-imidazol-1-ylmethyl)-1,1′-biphenyl (2) were performed, and the new phases were isolated and their crystal structures analysed. Profiling included methods such as PXRD and thermal analysis. Hirshfeld surface analyses, as well as crystal lattice energy calculations provided deeper insight in the interplay of the intermolecular forces and the stability of the isolated phases. Furthermore, our studies revealed the presence of solvent-induced polymorphism, whereby the metastable phase is dominant upon crystallisation from THF (1a) and EtOH (2c). Upon heating, these phases transform into a more stable form, whereby the transformations were followed by PXRD studies (1, 2).

Choi, Jaehoon; Zabihi, Omid; Ahmadi, Mojtaba; Naebe, Minoo

doi: 10.1039/d3ra05228apmid: 37859776

Structural batteries (SBs) have gained attention due to their ability to provide energy storage and structural support in vehicles and airplanes, using carbon fibers (CFs) as their main component. However, the development of high-performance carbon fiber-based cathode materials for structural batteries is currently limited. To address this issue, this study proposes a cost-efficient and straightforward method for creating a high-performance structural lithium iron phosphate (LiFePO4) positive electrode by coating carbon fibers at mild temperatures and pressures. The resulting cathode demonstrated a high LiFePO4 loading (at least 74%) and a smooth coating, as confirmed by X-ray spectroscopy, scanning electron microscopy, and Raman spectroscopy. This structural cathode exhibited a capacity of 144 mA h g−1 and 108 mA h g−1 at 0.1 C and 1.0 C, respectively. Additionally, the LiFePO4 cathode displayed excellent electrochemical properties, with a capacity retention of 96.4% at 0.33 C and 81.2% at 1.0 C after 300 cycles. Overall, this study presents a promising approach for fabricating high-performance structural batteries with enhanced energy storage and structural capabilities.

Kavya, Padmanabhan; Priya, Sudhesh; Pradeesh, Kannan; Sandeep, Kulangara; Saranya, Karisseri P.; Thomas, Vattaparambil Lucka; Shanthil, M.

doi: 10.1039/d3ra05023hpmid: 37881758

Semiconductor photocatalysts are promising cost-effective materials for degrading hazardous organic contaminants in water. Ag3PO4 is an efficient visible-light photocatalyst for the oxidation of water and dye degradation. The excited Ag3PO4 photocatalyst uses a hole to oxidise water or organic contaminants except the electron, which reduces Ag+ to Ag0. In the present study, the inherited disadvantage was overcome by a thin silica shell overcoating on Ag3PO4 nanoparticles. The silica-coated Ag3PO4 nanoparticles retain the photocatalytic activity even after five cycles of photodegradation, while the bare Ag3PO4 nanoparticles show a photocatalytic activity declined to half. The study demonstrates that the thin silica shell enhances the photostability, keeping the photocatalytic activity unaffected, even after several cycles of photodegradation of dyes. XPS analysis showed that the Ag0 formation on the surface of bare Ag3PO4 is greater than that on silica-coated Ag3PO4, which declines the photocatalytic activity of Ag3PO4 after five cycles of photodegradation. Electrochemical studies identified that the intermediates, such as OH˙ and O2−, formed during water oxidation play a crucial role in the photodegradation of dyes. This study can provide insights into the design of core–shell semiconductor nanostructures for reusable photocatalytic applications.

Cabrera-Munguia, Denis A.; Gutiérrrez-Alejandre, Aída; Romero-Galarza, Adolfo; Morales-Martínez, Thelma K.; Ríos-González, Leopoldo J.; Sifuentes-López, Jesús

doi: 10.1039/d3ra05774gpmid: 37859779

In this work, the xylose conversion and the selectivity to furfural were assessed over mesoporous sulfonic silica SBA-15-(X)SO3H catalysts doped with metal ions (X = Al(III), Ti(IV) or Zr(IV)). The type and amount of acid sites were analyzed by adsorption of pivalonitrile. The SBA-15-(X)SO3H materials show Lewis acid sites (LAS) and two types of Brønsted acid sites (BAS) with different strengths. Type I (BAS I) belongs to terminal silanol groups, type II (BAS II) is ascribed to hydroxyl groups bonded to sulfur or transition metal, and the LAS is related to M–O bonds. Optimal reaction conditions for the most active catalyst (SBA-15-(Zr)SO3H) were 120 minutes of reaction at 160 °C, 20 wt% of catalyst, and 2.5% of xylose/solvent. Additionally, a kinetic study was carried out to calculate the rate constants, the activation energy, and the pre-exponential factor for the xylose dehydration reaction. It was found that the selectivity to furfural in sulfonic silica SBA-15-(X)SO3H catalysts was directly related to the BAS II fraction. While LAS negatively impacts the selectivity to furfural leading to the undesired reaction between furfural and xylose obtaining humins as secondary products.

Timilsina, Arjun Prasad; Raut, Bimal Kumar; Huo, Chen; Khadayat, Karan; Budhathoki, Prakriti; Ghimire, Mandira; Budhathoki, Rabin; Aryal, Niraj; Kim, Ki Hyun; Parajuli, Niranjan

doi: 10.1039/d3ra04037bpmid: 37869390

Metabolomics and molecular networking approaches have expanded rapidly in the field of biological sciences and involve the systematic identification, visualization, and high-throughput characterization of bioactive metabolites in natural products using sophisticated mass spectrometry-based techniques. The popularity of natural products in pharmaceutical therapies has been influenced by medicinal plants with a long history of ethnobotany and a vast collection of bioactive compounds. Here, we selected four medicinal plants Cleistocalyx operculatus, Terminalia chebula, Ficus lacor, and Ficus semicordata, the biochemical characteristics of which remain unclear owing to the inherent complexity of their plant metabolites. In this study, we aimed to evaluate the potential of these aforementioned plant extracts in inhibiting the enzymatic activity of α-amylase and α-glucosidase, respectively, followed by the annotation of secondary metabolites. The methanol extract of Ficus semicordata exhibited the highest α-amylase inhibition with an IC50 of 46.8 ± 1.8 μg mL−1, whereas the water fraction of Terminalia chebula fruits demonstrated the most significant α-glucosidase inhibition with an IC50 value of 1.07 ± 0.01 μg mL−1. The metabolic profiling of plant extracts was analyzed through Liquid Chromatography-Mass Spectrometry (LC-HRMS) of the active fractions, resulting in the annotation of 32 secondary metabolites. Furthermore, we applied the Global Natural Product Social Molecular Networking (GNPS) platform to evaluate the MS/MS data of Terminalia chebula (bark), revealing that there were 205 and 160 individual ion species observed as nodes in the methanol and ethyl acetate fractions, respectively. Twenty-two metabolites were tentatively identified from the network map, of which 11 compounds were unidentified during manual annotation.

Lin, Minggang; Shen, Jinlin; Wang, Bingbing; Chen, Yangyi; Zhang, Chuyang; Qi, Huan

doi: 10.1039/d3ra05969cpmid: 37869388

Electrospun nanofiber membranes have been extensively studied as air filters. However, their limited filtration efficiency for submicron inhalable particulate matter (PM), high resistance to filtration, and limited capacity to hold dust have hindered their widespread use. The majority of materials come from petroleum, and the use of organic solvents during the spinning process has a significant negative impact on the environment. In this work, a sustainable method has been proposed for producing filters using poly(lactic acid) (PLA) with a bimodal diameter distribution through conjugated electrospinning. This technique allows for the continuous production of interconnected micro/nano hybrid porous membranes, resulting in reduced resistance and improved dust holding capacity. The filtration efficiency, pressure drop, long-term filtration performance, and actual performance of the conjugated bimodal membrane (CBM) were extensively investigated. The results indicate that the filter has a high capacity for retaining particles, with filtration efficiencies of 99.94% for PM 0.3 and 99.96% for PM 2.5. It also demonstrates a high quality factor (0.078 Pa−1 for PM 0.3 and 0.084 Pa−1 for PM 2.5), long-term stability (a decrease of 2.35% for PM 0.3 and 0.05% for PM 2.5 over a period of 60 days) and outstanding dust holding capacity (9.17 g m−2). The conjugated bimodal membrane (CBM) shows a 22.64% decrease in resistance compared to the non-conjugated bimodal membrane (BM). In general, the approach outlined in this work provides valuable insights into the development of high-performance biodegradable air filters. These filters have improved filtration efficiency and reduced resistance.