Small

doi: 10.1002/smll.201570252pmid: N/A

Jang, Seonpil; Kim, Bongjun; Geier, Michael L.; Hersam, Mark C.; Dodabalapur, Ananth

doi: 10.1002/smll.201570248pmid: N/A

For short‐channel field‐effect transistors with inkjet‐printed semiconducting carbon nanotubes, a novel fabrication strategy is developed by M. C. Hersam, A. Dodabalapur, and co‐workers to minimize material consumption. On page 5505 they show how a single droplet of 10 pL ink containing 0.5 pg of nanotubes can be used, confining the inkjet droplet into the active channel area. This fabrication approach is compatible with roll‐to‐roll processing and enables the formation of high‐performance short channel device arrays based on inkjet printing.

Fang, Ronnie H.; Kroll, Ashley V.; Zhang, Liangfang

doi: 10.1002/smll.201570249pmid: N/A

On page 5483, L. Zhang and co‐workers describe the process of nanoparticle‐mediated antigen presentation. A dendritic cell takes up cell membrane‐coated nanoparticles that are loaded with an immunological adjuvant. After uptake, the tumor antigens on the nanoparticle‐stabilized membrane are processed and presented on the surface of the dendritic cell. Meanwhile, the adjuvant is released and causes the dendritic cell to mature, ultimately enabling it to activate tumor antigen‐specific T cells (shown here as green).

doi: 10.1002/smll.201570250pmid: N/A

Labram, John G.; Lin, Yen‐Hung; Anthopoulos, Thomas D.

doi: 10.1002/smll.201501350pmid: 26349850

In the last decade, metal oxides have emerged as a fascinating class of electronic material, exhibiting a wide range of unique and technologically relevant characteristics. For example, thin‐film transistors formed from amorphous or polycrystalline metal oxide semiconductors offer the promise of low‐cost, large‐area, and flexible electronics, exhibiting performances comparable to or in excess of incumbent silicon‐based technologies. Atomically flat interfaces between otherwise insulating or semiconducting complex oxides, are also found to be highly conducting, displaying 2‐dimensional (2D) charge transport properties, strong correlations, and even superconductivity. Field‐effect devices employing such carefully engineered interfaces are hoped to one day compete with traditional group IV or III–V semiconductors for use in the next‐generation of high‐performance electronics. In this Concept article we provide an overview of the different metal oxide transistor technologies and potential future research directions. In particular, we look at the recent reports of multilayer oxide thin‐film transistors and the possibility of 2D electron transport in these disordered/polycrystalline systems and discuss the potential of the technology for applications in large‐area electronics.

Fang, Ronnie H.; Kroll, Ashley V.; Zhang, Liangfang

doi: 10.1002/smll.201501284pmid: 26331993

Immunotherapeutic approaches for treating cancer overall have been receiving a considerable amount of interest due to the recent approval of several clinical formulations. Among the different modalities, anticancer vaccination acts by training the body to endogenously generate a response against tumor cells. However, despite the large amount of work that has gone into the development of such vaccines, the near absence of clinically approved formulations highlights the many challenges facing those working in the field. The generation of potent endogenous anticancer responses poses unique challenges due to the similarity between cancer cells and normal, healthy cells. As researchers continue to tackle the limited efficacy of vaccine formulations, fresh and novel approaches are being sought after to address many of the underlying problems. Here the application of nanoparticle technology towards the development of anticancer vaccines is discussed. Specifically, there is a focus on the benefits of using such strategies to manipulate antigen presenting cells (APCs), which are essential to the vaccination process, and how nanoparticle‐based platforms can be rationally engineered to elicit appropriate downstream immune responses.

Lee, Seungae; Hong, Jin‐Yong; Jang, Jyongsik

doi: 10.1002/smll.201570251pmid: N/A

A transparent, free‐standing, conducting polypyrrole film is composed of highly uniform polypyrrole nanoparticles. As shown on page 5498 by J. Jang and co‐workers, the film is composed of highly uniform and densely packed polypyrrole nanoparticles. Because of this structure, the free‐standing polypyrrole film exhibits high transparency, flexibility, electrical conductivity, and stable mechanical properties. The schematic illustration in this image represents these outstanding properties of the film.

Lee, Seungae; Hong, Jin‐Yong; Jang, Jyongsik

doi: 10.1002/smll.201501752pmid: 26332082

Transparent, free‐standing, conducting polypyrrole (PPy) film is successfully fabricated by a simple method using the spin‐coating technique. The free‐standing PPy film exhibits high transparency, flexibility, electrical conductivity, and stable mechanical properties because the PPy film is composed of densely packed and highly ordered PPy nanoparticles. This approach provides feasible candidate for applications requiring flexible and conducting materials.

Jang, Seonpil; Kim, Bongjun; Geier, Michael L.; Hersam, Mark C.; Dodabalapur, Ananth

doi: 10.1002/smll.201501179pmid: 26312458

Short channel field‐effect‐transistors with inkjet‐printed semiconducting carbon nanotubes are fabricated using a novel strategy to minimize material consumption, confining the inkjet droplet into the active channel area. This fabrication approach is compatible with roll‐to‐roll processing and enables the formation of high‐performance short channel device arrays based on inkjet printing.

Xianyu, Yunlei; Xie, Yangzhouyun; Wang, Nuoxin; Wang, Zhuo; Jiang, Xingyu

doi: 10.1002/smll.201500903pmid: 26313890

A dispersion‐dominated chromogenic strategy for glutathione sensing is developed. Glutathione prevents the aggregation of arginine‐modified gold nanoparticles via mercury–thiol interaction, which allows for glutathione sensing at the nanomolar level (10.9 × 10−9 m) with facile operation and naked‐eye readout.