Dalton Transactions

doi: 10.1039/C8DT90027Bpmid: N/A

doi: 10.1039/c8dt90027bpmid: N/A

doi: 10.1039/c8dt90028kpmid: N/A

doi: 10.1039/C8DT90028Kpmid: N/A

doi: 10.1039/C8DT90029Apmid: N/A

doi: 10.1039/c8dt90029apmid: N/A

Chen, Wei; Wu, Chunsheng

doi: 10.1039/c7dt04116kpmid: 29369314

Metal–organic frameworks (MOFs), also known as coordination polymers, have attracted extensive research interest in the past few decades due to their unique physical structures and potentially vast applications. In this review, we outline the recent progress in the synthesis, functionalization and applications of MOFs in biomedicine, mainly focusing on two promising, yet challenging areas, i.e., drug delivery and biosensing applications. A major challenge is the proper functionalization of MOFs with demanding properties suitable for biomedical applications. Extensive studies on MOFs in biomedicine have led to substantial progress in the control of key properties of MOFs such as toxicity, size and shape, and biological stability. Due to their flexible composition, pore size and easy functionalization properties, MOFs can be utilized as key components for the development of various functional systems, and their applications in drug delivery and biosensing are reviewed. Future trends and perspectives in these research areas are also outlined.

Chen, Shuai; Narayanam, Nagaraju; Zhang, Lei; Zhang, Jian

doi: 10.1039/c7dt04112hpmid: 29355266

Two enantiomorphic helical chains were constructed using heterometallic {TiMn2(μ3-O)} building units, and their final homochiral lattice packing was further transmitted by hydrogen bonding interactions between the chains with the same handedness.

Erickson, Karla A.; Cibuzar, Michael P.; Mucha, Neil T.; Waterman, Rory

doi: 10.1039/c7dt04507gpmid: 29363696

Exploration of (N3N)ZrNMe2 (1, N3N = N(CH2CH2NSiMe3)33–) as a catalyst for the cross-dehydrocoupling or heterodehydrocoupling of silanes and amines suggested silylene reactivity. Further studies of the catalysis and stoichiometric modeling reactions hint at α-silylene elimination as the pivotal mechanistic step, which expands the 3p elements known to engage in this catalysis and provides a new strategy for the catalytic generation of low-valent fragments.

Wu, Jia-Wei; Wang, Xue; Tian, Chong-Bin; Du, Shao-Wu

doi: 10.1039/c7dt04820cpmid: 29372734

A new 3D MOF [MnLi2(ip)2(H2O)2] (1) with a 1D heterometallic inorganic Mn(ii)–Li(i) chain is reported. With the assistance of diamagnetic {LiO4} connectors, which separate the paramagnetic Mn(ii) ions and act as magnetic spacers, very weak magnetic interactions were obtained. Remarkably, 1 showed a significant magnetocaloric effect (MCE) with a large entropy change value of 30.4 J kg−1 K−1 for ΔH = 8 T at 2 K.