Nature Cell Biology

doi: 10.1038/ncb0904-793pmid: 15340437

Hayward, Richard D.; Phillips, Neil; Koronakis, Vassilis

doi: 10.1038/ncb0904-795bpmid: N/A

Swimm, Alyson; Bommarius, Bettina; Reeves, Patrick; Sherman, Melanie; Kalman, Daniel

doi: 10.1038/ncb0904-795apmid: 15340438

Maienschein, Jane

doi: 10.1038/ncb0904-797pmid: N/A

Cashman, Neil R.

doi: 10.1038/ncb0904-798pmid: N/A

Klug, Aaron

doi: 10.1038/ncb0904-799pmid: 15340442

Hoyt, M. Andrew

doi: 10.1038/ncb0904-801pmid: 15340443

Cell duplication requires the coordination of nuclear division with diverse cellular morphogenesis events, such as cell wall growth. A novel checkpoint has been identified in yeast that coordinates these two events. Unexpectedly, the dynein-activating dynactin complex, but not dynein itself, is an essential component of this checkpoint mechanism.

Mcdonald, Donald

doi: 10.1038/ncb0904-803pmid: 15340444

Martin, Seamus J.

doi: 10.1038/ncb0904-804pmid: 15340445

Proteins containing the BIR motif have been implicated as regulators of apoptosis and cell division. Apollon, an exceptionally large BIR-containing protein, inhibits apoptosis by targeting key cell death proteins for destruction by the ubiquitin-proteasome pathway. Now, deletion of apollon in the mouse has revealed a crucial function in cell division.

Pulverer, Bernd

doi: 10.1038/ncb0904-806pmid: 15340446