Virchows Archiv

Klein, H.; Gheorghiu, Th.; Hübner, G.; Eder, M.

doi: 10.1007/BF00600670pmid: N/A

Gastric secretion and the development of gastric lesions were studied in the rat under total restraint. Three phases can be distinguished: The first one lasts about 3 hours and is characterised by functional vascular disturbances in the deeper layers of the gastric wall, especially by a constriction of the arteriolae in the submucosa. It follows a second phase with trophic alteration of the mucosa by hypoxia and stasis in the capillaries of the mucosa itself. At this time (about 5 hours after beginning of the experiment) moderate amounts of gastric juice with a high concentration of hydrochloric acid are secreted. Its action on the altered mucosa is intensified by the contraction of the gastric wall, which guarantees a close contact of the stagnant acid juice with the mucous membrane. About one hour after the peak of acid secretion, in a third phase, irreversible changes in form of erosions and ulcerations of the gastric mucosa can be observed.

Stiller, Dankwart; Katenkamp, Detlef

doi: 10.1007/BF00600671pmid: N/A

Investigations on the pathogenesis of senile amyloidosis were carried out on the hearts of old men using histochemical, polarizing and fluoresence microscopic methods.

Sack, K.; Henkel, W.; Commichau, R.

doi: 10.1007/BF00600672pmid: 4929125

Since a chronic non-obstructive coli-pyelonephritis (pn) could not be induced in animals up to the present date, albino Wistar rats were infected endovesically with the O 25:19:12 strain of E. coli. The histological and bacteriological changes were followed up to 90 days. During the test-interval the animals received 0.5 mg estradiol-undecylate/kg/week i.m.

Vogel, A.

doi: 10.1007/BF00600673pmid: N/A

Intestinal biopsies from 54 children with different forms of malabsorption syndrome and with other diseases were evaluated histologically. Criteria for evaluation were: the length of crypts and villi, the index of mitosis, the quantity of Paneth cells and the type of cells in the lamina propria.

Hofmann, W.

doi: 10.1007/BF00600674pmid: N/A

Human, calf, chicken, and pig aortas (ten each) were examined histologically, histochemically, and chromatographically. It was shown that as arteriosclerosis begins to develop the so-called intimal edema is either free of fat or almost free of fat. That means the fat-free intimal edema is able to induce the arteriosclerotic changes, which develop later take place.

Marti, M.; Bouchardy, B.; Cox, J.

doi: 10.1007/BF00600675pmid: 5313872

The histological modifications in 8 cases of autologous aorto-coronary saphenous vein grafts were studied. In the early stages, these showed intimal thickening and medial hypertrophy, particularly affecting the middle circular layer. The intimal thickening progressed, and the media later became largely replaced by dense fibrous tissue. No aneurysmal dilatations were observed, but in 3 cases the grafts were thrombosed. The pathogenesis of these changes is discussed.

Wurster, K.

doi: 10.1007/BF00600676pmid: N/A

The malignant Brenner tumour is rare; in some cases it develops from the benign form of the tumour.

Döhnert, Götz

doi: 10.1007/BF00600677pmid: 5313874

This report is about a 68 year old man who died of a tonsillar lymphoepithelial carcinoma. The wide-spread metastases called attention to the tumor. Considerations about the diagnostic difficulties, the etiology and the proper position of the tumor are made. Based on literature and autopsy findings the justification for continuing to use the term “lymphoepithelioma” is discussed and defended.