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Atrial fibrillation is the most frequently encountered sustained arrhythmia in clinical practice. To date, therapy of paroxysmal atrial fibrillation (AF) has been mainly directed to prevent AF recurrences. In the initial step, pharmacological treatment is the therapy of primary choice. Frequent...
Although several classical studies seemed to provide clear ideas on the pathophysiology of atrial fibrillation, current concepts have to be modified on the basis of more recent findings.
Atrial fibrillation and related arrhythmias are common after cardiac surgery. As more and more elderly patients are operated on for cardiac diseases, the interest in this arrhythmia is growing again. There are some unresolved problems of this complication.
ta-blocker STrategy plus Implantable Cardioverter Defibrillator (BEST + ICD) Trial is a multicenter prospective randomized study in which the hypothesis will be tested of whether, in high-risk post-myocardial infarction (MI) patients already treated with β-blockers, therapy guided by...
The theraputic efficiency of implantable defibrillators in patients with life threatening ventricular tachyarrhythmias has, meanwhile, been proven. Therefore, the cost efficacy of this form of therapy is moving increasingly to the center of focus. Studies about cost efficacy were at the...
Atrial fibrillation is the most commonly encountered sustained arrhythmia in men. It is associated with a two-fold mortality risk and an increased cost for health care providers. The relative inefficacy and the risks of pharmacologic approaches to atrial fibrillation therapy have contributed to...
The design of controlled clinical trials on prevention and therapy of arrhythmic events is a difficult task. In particular in ICD trials, false estimations and omissions have occured that can compromise the interpretation of a trial.
CHD mortality has shown a decreasing trend since the early 1980s. Nonetheless, two of three coronary deaths die before hospitalization.
Catheter ablation is an established method to treat paroxysmal supraventricular tachyarrhythmias. However, the risks of catheter ablation have to bee weight against antiarrhythmic therapy. With catheter ablation AV-block III°, pulmonary embolism, pericardial tamponade (in some cases followed by...
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