Observations on anatomical dead space during general onanatomicalanaesthesiaDéry, R.; Pelletier, J.; Jacques, A.
doi: 10.1007/BF03005089pmid: 14210599
The determination of anatomical dead space is proposed as a suitable means to indirect appreciation of changes induced by anaesthetic agent on broncho-motor tone and bronchial calibre Such determinations were performed in 36 patients prior to, during, and after anaesthesia produced with hilothane, thiopentone, methoxyflurane, and with the azeotropic mixture of halothane-ether No significant changes were observed with halothane Thiopentohe administrition induced a consistent reduction m anatomical dead space Signiicantly higher values, however, were found during methoxyflurane and halothane-ether anaesthesia, a finding we interpreted as bronchodiatation We suggest that the mechanism underying the production of these variations in airway calibre is one of autonomic imbalance between sympathetic broncho-dilator and parasympathetic bronchoconstrictor fibres, although either a dirqet action of anaesthetic drugs on bronchia smooth muscle itself or an indirect humoral approach may well be mvolved
Anaesthesia for laryngoscdpy and bronchoscopy in childrenKay, Brian; Allan, David
doi: 10.1007/BF03005093pmid: 14210602
Some of the optimal surgical requirements for anaesthesia for bronchoscopy and laryngoscopy m children are considered Some limitations of several previously suggested methods of anaesthesia are observed, and a means of producing the required operating conditions suggested, using anaesthetic agents with the most suitable pharmacological properties It is suggested that anaesthesia of the larynx and trachea is best produced by precise topical applications of 4 per cent lignocaine, and unconsciousness best provided by the recovery period following induction with methoxyflurane