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Wyant, Gordon M.; Chang, Chung Ai; Aasheim, Geordis M.
doi: 10.1007/bf03014128pmid: 13561131
SummaryThe properties of methitural with and without premedication have been compared in a series of patients m physical status I and II and of comparable age, height and weight, undergoing minor gynaecological procedures.Sodium thiopental was approximately twice as potent as sodium methitural, and for comparable depth and duration of anaesthesia, the waking period after methitural was the same as that following thiopental.The incidence of cough and hiccough was greater under methitural anaesthesia. Hiccoughs, when they occurred, tended to persist throughout the procedure and were also seen in the emergence period. Gross movements were seen only with methitural. Patients were more widely awake and less disorientated after methitural anaesthesia, but showed a higher incidence of nausea and vomiting. The apnoea following an induction dose of methitural was on the average of shorter duration than that following sodium thiopental and its incidence was lower. Muscle relaxation for such procedures as bimanual pelvic examination was more often satisfactory with methitural anaesthesia.Preoperative medication reduced the amount of methitural required to maintain anaesthesia and decreased the incidence of side-effects.
Marshall, Brian M.; Gordon, R. A.
doi: 10.1007/bf03014129pmid: 13561132
SummaryThis paper presents a review of literature dealing with regurgitation and aspiration and reports a study of the incidence of regurgitation and aspiration in surgical and obstetrical anaesthesia The clinical and pathological findings are described and factors contributing to regurgitation and aspiration are discussed The anaesthetic factors are described and discussed with reference to the study made by the authors A comparison follow-up study of one group of patients with a high incidence of reguigitation and aspiratior is made with a similar group of patients anaesthetized twenty years ago A possible reason for the marked decrease in postoperative pulmonary complications is presentedA subsequent article will present case histories and discuss treatment and sequelae of aspiration during anaesthesia
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