Schizophrenia Bulletin

Myslobodsky, Michael, S.

doi: 10.1093/schbul/12.1.1pmid: 2870563

Abstract Wilson et al. (1983) called attention to the increasing incidence of affective symptomatology in schizophrenic patients on chronic neuroleptic medication. They designated the emerging syndrome as tardive dysmentia in order to emphasize its connection with the pathophysiology of tardive dyskinesia. The present contribution suggests that the emotional indifference or frank anosognosia of abnormal involuntary movements noted in the great majority (95 percent) of patients with tardive dyskinesia is another possible feature of tardive dysmentia. An attempt was made to explain anosognosia, and some difficulties that mar interpretation of data were pointed out. Anosognosia was proposed to represent a symptom related to some sort of cognitive disorder accompanying tardive dyskinesia, at least in the elderly. It was suggested that dementia may be associated with a predominant impairment of dopaminergic circuitry in the right cerebral hemisphere. This content is only available as a PDF. © Oxford University Press

Myslobodsky, Michael S.

doi: N/Apmid: N/A

Wilson et al. (1983) called attention to the increasing incidence of affective symptomatology in schizophrenic patients on chronic neuroleptic medication. They designated the emerging syndrome as tardive dysmentia in order to emphasize its connection with the pathophysiology of tardive dyskinesia. The present contribution suggests that the emotional indifference or frank anosognosia of abnormal involuntary movements noted in the great majority (95 percent) of patients with tardive dyskinesia is another possible feature of tardive dysmentia. An attempt was made to explain anosognosia, and some difficulties that mar interpretation of data were pointed out. Anosognosia was proposed to represent a symptom related to some sort of cognitive disorder accompanying tardive dyskinesia, at least in the elderly. It was suggested that dementia may be associated with a predominant impairment of dopaminergic circuitry in the right cerebral hemisphere.

Myslobodsky, Michael S.

doi: 10.1093/schbul/12.1.1pmid: 2870563

Wilson et al. (1983) called attention to the increasing incidence of affective symptomatology in schizophrenic patients on chronic neuroleptic medication. They designated the emerging syndrome as tardive dysmentia in order to emphasize its connection with the pathophysiology of tardive dyskinesia. The present contribution suggests that the emotional indifference or frank anosognosia of abnormal involuntary movements noted in the great majority (95 percent) of patients with tardive dyskinesia is another possible feature of tardive dysmentia. An attempt was made to explain anosognosia, and some difficulties that mar interpretation of data were pointed out. Anosognosia was proposed to represent a symptom related to some sort of cognitive disorder accompanying tardive dyskinesia, at least in the elderly. It was suggested that dementia may be associated with a predominant impairment of dopaminergic circuitry in the right cerebral hemisphere.

Grau, Barry W.; Mueser, Kim T.

doi: 10.1093/schbul/12.1.7pmid: 3961428

The issue ofthe dimensionality of negative symptoms is addressed. In reference to datareported by Lewine, Fogg, and Meltzer(1983), it is suggested that the nonsignificantcorrelation between a SADS–C negative symptom scale and a NOSIEnegative symptom scale, both independently developed using the Rasch model, isevidence for the multidimensionality of negative symptoms. Additional datasupporting the multidimensionality of negative symptoms using confirmatoryfactor analysis is also discussed (Gibbons et al. 1985). A new theory for the structure ofnegative symptoms is needed, which specifies the number of dimensions, theirclassification, and their pattern of intercorrelation.

Grau, Barry, W.;Mueser, Kim, T.

doi: 10.1093/schbul/12.1.7pmid: 3961428

Abstract The issue of the dimensionality of negative symptoms is addressed. In reference to data reported by Lewine, Fogg, and Meltzer (1983), it is suggested that the nonsignificant correlation between a SADS-C negative symptom scale and a NOSIE negative symptom scale, both independently developed using the Rasch model, is evidence for the multidimensionality of negative symptoms. Additional data supporting the multidimensionality of negative symptoms using confirmatory factor analysis is also discussed (Gibbons et al. 1985). A new theory for the structure of negative symptoms is needed, which specifies the number of dimensions, their classification, and their pattern of intercorrelation. This content is only available as a PDF. © Oxford University Press

Grau, Barry W.; Mueser, Kim T.

doi: N/Apmid: N/A

The issue ofthe dimensionality of negative symptoms is addressed. In reference to datareported by Lewine, Fogg, and Meltzer(1983), it is suggested that the nonsignificantcorrelation between a SADS–C negative symptom scale and a NOSIEnegative symptom scale, both independently developed using the Rasch model, isevidence for the multidimensionality of negative symptoms. Additional datasupporting the multidimensionality of negative symptoms using confirmatoryfactor analysis is also discussed (Gibbons et al. 1985). A new theory for the structure ofnegative symptoms is needed, which specifies the number of dimensions, theirclassification, and their pattern of intercorrelation.

Lewine, Richard, R.J.

doi: 10.1093/schbul/12.1.9pmid: N/A

Abstract Grau and Mueser (this issue) use the modest correlation between two negative symptom scales (Lewine, Fogg, and Meltzer 1983) to argue for the rejection of the Rasch model upon which the development of the scales was based. Their analysis fails, however, to take into account the conceptual and methodological intricacies of research assessment in clinical settings. Any sweeping generalization at this point is premature and risks the loss of heuristically valuable models. This content is only available as a PDF. © Oxford University Press

Lewine, Richard R. J.

doi: N/Apmid: N/A

Grau andMueser (this issue) use the modest correlation between two negative symptomscales (Lewine, Fogg, and Meltzer1983) to argue for the rejection of the Rasch model uponwhich the development of the scales was based. Their analysis fails, however, totake into account the conceptual and methodological intricacies of researchassessment in clinical settings. Any sweeping generalization at this point ispremature and risks the loss of heuristically valuable models.

Lewine, Richard R. J.

doi: 10.1093/schbul/12.1.9pmid: N/A

Grau andMueser (this issue) use the modest correlation between two negative symptomscales (Lewine, Fogg, and Meltzer1983) to argue for the rejection of the Rasch model uponwhich the development of the scales was based. Their analysis fails, however, totake into account the conceptual and methodological intricacies of researchassessment in clinical settings. Any sweeping generalization at this point ispremature and risks the loss of heuristically valuable models.

Harrod, James B.

doi: N/Apmid: N/A

Lanin-Kettering and Harrow (1985) argue the traditional position that schizophrenia is a thought disorder. Chaika and Lambe (1985) counter that it is a speech disorder at the syntactic-discursive level, and not a thought disorder. On the basis of state-of-the-art research in linguistics, it is suggested that the symptoms of schizophrenia are evidence of neither a thought disorder nor a syntactic-discursive disorder but a semiotic disorder. Semiotic structures have the form of saying something about something to someone and involve speech act, reference, pragmatics, and interpretation. Therefore, it appears that schizophrenic disorder is located in this structure.