Ultrasonic Diagnosis of Early Breast CancerClinical Significance of Gray Scale Expanded EchographyKOBAYASHI,, TOSHIJI;NAGATA,, FUMIKO;SHINODA,, AKIKO;NAKAMURA,, SHIGEKO;TANABE,, SHIGEKO;TAKATANI,, OSAMU
doi: 10.1093/oxfordjournals.jjco.a039892pmid: N/A
Abstract Differential diagnosis of early breast cancer was performed by various echographic display techniques such as a sensitivity graded method, gray scale echography and the expanded echography of two dimensional (B-scan) ultrasonography on 541 cases. The clinical significance of gray scale expanded echography for target enlargement was evaluated for early breast cancer on 37 cases histologically verified. Differential criteria for this technique is reported and bio-acoustic mechanisms for the appearance of such differential points are discussed. Diagnostic accuracy rate improved for early breast cancer below 2.0 cm in size, while the false positive rate remained the same. This content is only available as a PDF. © Oxford University Press
Peritoneoscopic Classification of Cavernous Hemangiomas of the LiverYOSHINO,, MASAHIRO;OKAZAKI,, NOBUO;YOSHIDA,, TAKANOBU
doi: 10.1093/oxfordjournals.jjco.a039893pmid: N/A
Abstract The peritoneoscopic findings of cavernous hemangiomas of the liver observed in seven cases were classified into the following four types. Type I: Patches, mostly disseminated. Dark or purplish blue in color. Type II: Localized protuberance, like a cutaneous cavernous hemangioma with various colors. Type III: Cystic mass, mostly dark blue in color. Type IV: Diffuse protuberance of the liver surface due to occult mass. In giant hepatic cavernous hemangiomas, usually two or more types of hemangiomas were observed on the surface of the same liver. These various features of hepatic hemangiomas could be defined by the size of the hemangioma, its location within the liver and the nature of its capsule. This content is only available as a PDF. © Oxford University Press
Cytodifferentiation to Serous and Myoepithelial Cells in Salivary Gland and Salivary Gland Type TumorsKAMEYA,, TORU;SHIMOSATO,, YUKIO;TAKEUCHI,, TOSHIYUKI;SASADAIRA,, SHUICHI
doi: 10.1093/oxfordjournals.jjco.a039894pmid: N/A
Abstract Three-hundred-and-three cases of salivary gland and salivary gland type tumors in the head and neck and lower respiratory tract, treated in our institution, were reviewed histologically. Some of these cases were analyzed; 51 arbitrarily selected cases by conventional stainings, 15 cases by immunostainings for amylase and actomyosin, and 22 cases by electron microscopy for cellular differentiation to serous and myoepithelial cells For morphological and biochemical comparison, six cases of ectopic amylase-producing tumor were also studied Serous acmar cells contained amylase and basaly located cells of acini and ducts contained actomyosin in non-neoplastic salivary glands Although zymogen type granules were barely observed except in a case of acinic cell carcinoma of the palate and in a case of adenocarcinoma of the lung by light and electron microscopy, some tumor cells contained amylase which seemed to be specific of salivary gland tumor in three cases and of ectopic amylase-producing tumor in three cases, confirmed by immunofluorescent microscopy, enzyme assay and electrophoresis of the tumor tissues In cases of mixed tumor, adenoid cystic carcinoma, and mucoepidermoid carcinoma, cells reactive to anti-actomyosin were often encountered in the outer layer of duct-like structures By electron microscopy, location of myoepithelium-like cells was in accord-ance with that of actomyosin-positive cells in some instances Coexistence of tonofibrils and myofilaments in one and the same cell was occasionally seen This content is only available as a PDF. Author notes * Present address: Department of Pathology, Tokai University School of Medicine, Kana gawa, Japan. © Oxford University Press
A Case of Locally Cured Lung Cancer by Bronchial Arterial Infusion of Anti-Cancer DrugsMIYAZAWA,, NAOTO;AMEMIYA,, RYUTA;SUZUKI,, HIROSHI
doi: 10.1093/oxfordjournals.jjco.a039895pmid: N/A
Abstract Cure of lung cancer only by anti-cancer drugs is rare. A case with bronchogenic carcinoma, which was histologically confirmed to be keratotic squamous cell carcinoma from the bronchoscopically biopsied specimen, was given local infusion of anti-cancer drugs through the bronchial artery as an adjuvant to the surgery. Three weeks later, lobectomy was performed. However, the resected specimen did not contain any cancer tissue and instead cicatrix had replaced the whole area where cancer had presumably existed before the drug infusion. These evidences disclosed a histopathological local cure of cancer. This content is only available as a PDF. © Oxford University Press
Six Cases of Carcinosarcoma of the EsophagusIIZUKA,, TOSHIFUMI;HIRATA,, KATSUJI;WATANABE,, HIROSHI;INUKAI,, HIDENORI;HIROTA,, TERUYUKI;ITABASHI,, MASAYUKI
doi: 10.1093/oxfordjournals.jjco.a039897pmid: N/A
Abstract Clinical aspects of six cases of esophageal carcinosarcoma were reported. They were all male in their sixties. Although almost all cases of carcinosarcoma of the esophagus reported in the literatures had polypoid lesions, two of our cases showed ulcerative appearance and were not considered to be carcinosarcoma by macroscopic observations. Recently, preoperative irradiation has been adopted for the treatment of esophageal carcinoma in many hospitals and it may be possible that some of sarcomatous component has disappeared at the time of operation. Therefore, more cases of esophageal carcinosarcoma could be present among those who had been diagnosed as esophageal carcinoma. This content is only available as a PDF. © Oxford University Press
A Case of Small Cell Carcinoma of the Lung Producing ADH, ACTH, MSH and Calcitonin: Successful Treatment of Severe Hyponatremia with Furosemide and Hypertonic SalineYAMAGUCHI,, KEN;ABE,, KAORU;ADACHI,, ISAMU;TANAKA,, NOBUYOSHI;TANAKA,, MASAHIRO;MIYAKAWA,, SUMIKO;KAMEYA,, TORU;KIMURA,, TOKIHISA
doi: 10.1093/oxfordjournals.jjco.a039888pmid: N/A
Abstract A 48-year-old man with a small cell carcinoma of the lung presented hyponatremia and was diagnosed as having the syndrome of inappropriate ADH secretion. A plasma ADH bioassay confirmed this syndrome. During the clinical course, the patient developed a hyponatremic crisis with a serum sodium of 108mEq/l. His hyponatremia was rapidly corrected by infusing furosemide in conjunction with hypertonic saline. The postmortem studies demonstrated ADH bioactivity in the tumor tissues, as well as immunoreactive ACTH, β-MSH and calcitonin. Tumor hypersecretion of ACTH appeared to be the cause of the patient's hyperresponsiveness to exogenous ACTH and of the bilateral adrenocortical hyperplasia observed at the time of autopsy. Therefore, this was a case of a multiple hormone-producing small cell carcinoma of the lung, in which the severe clinical manifestations of SIADH were successfully treated with furosemide and hypertonic saline. This content is only available as a PDF. © Oxford University Press
Parathyroid Cyst as a Cervical or Cervicomediastinal MassFUJIMOTO,, YOSHIHIDE;OBARA,, TAKAO;MIURA,, TSUYOSHI
doi: 10.1093/oxfordjournals.jjco.a039889pmid: N/A
Abstract Three cases of parathyroid cyst are reported. The cysts were invariably located in the lower neck and presented a typical cystic pattern on ultrasound scanning. A thin-needle aspiration of the cyst readily yielded transparent, watery fluid containing a high titer of immunoreactive parathyroid hormone (PTH). These findings confirmed the diagnosis of parathyroid cyst. At the time of operation, thickening of the cyst wall and adhesion to the surrounding structures were found. These unusual findings were thought to be induced by previous punctures. In one case, there was a large cyst extending into the mediastinum and causing partial respiratory obstruction—a condition requiring prompt surgical removal of the cyst. This content is only available as a PDF. © Oxford University Press