On construction of constant block-sum partially balanced incomplete block designsKhattree, Ravindra
doi: 10.1080/03610926.2019.1576895pmid: N/A
AbstractConstant block-sum designs are of interest in repeated measures experimentation where the treatments levels are quantitative and it is desired that at the end of the experiments, all units have been exposed to the same constant cumulative dose. It has been earlier shown that the constant block-sum balanced incomplete block designs do not exist. As the next choice, we, in this article, explore and construct several constant block-sum partially balanced incomplete block designs. A natural choice is to first explore these designs via magic squares and Parshvanath yantram is found to be especially useful in generating designs for block size 4. Using other techniques such as pair-sums and, circular and radial arrangements, we generate a large number of constant block-sum partially balanced incomplete block designs. Their relationship with mixture designs is explored. Finally, we explore the optimization issues when constant block-sum may not be possible for the class of designs with a given set of parameters.
Inference of the derivative of nonparametric curve based on confidence distributionLi, Na; Liu, Xuhua
doi: 10.1080/03610926.2019.1576896pmid: N/A
AbstractThis paper focuses on inference based on the confidence distributions of the nonparametric regression function and its derivatives, in which dependent inferences are combined by obtaining information about their dependency structure. We first give a motivating example in production operation system to illustrate the necessity of the problems studied in this paper in practical applications. A goodness-of-fit test for polynomial regression model is proposed on the basis of the idea of combined confidence distribution inference, which is the Fisher’s combination statistic in some cases. On the basis of this testing results, a combined estimator for the p-order derivative of nonparametric regression function is provided as well as its large sample size properties. Consequently, the performances of the proposed test and estimation method are illustrated by three specific examples. Finally, the motivating example is analyzed in detail. The simulated and real data examples illustrate the good performance and practicability of the proposed methods based on confidence distribution.
Assurance test and its equivalent truncated sequential testHu, Sigui; Wang, Honglei
doi: 10.1080/03610926.2019.1576897pmid: N/A
AbstractIn order to save more test cost, assurance test and its equivalent truncated sequential test are studied. In a commonly used case, the operating characteristic (OC) function and expected test time (ETT) function of an assurance test are derived in a concise way. Equivalent test and relative concepts are defined. The procedures to construct a near equivalent truncated sequential test of an assurance test are established. Computation studies show that the near equivalent truncated sequential tests proposed in this paper keep almost the same OC curves with the assurance tests respectively. However, they can save the ETTs dramatically. In fact, the results show that the near equivalent truncated sequential tests can save around 50% of ETTs than the assurance tests respectively.
Use of scrambled response for estimating mean of the sensitivity variableSanaullah, Aamir; Saleem, Iram; Shabbir, Javid
doi: 10.1080/03610926.2019.1576898pmid: N/A
AbstractIn this article, we propose new efficient and more generalized difference-cum-exponential type estimator and generalized-difference-cum-generalized exponential type estimators for estimating the mean of sensitivity variable using the auxiliary information. We also discuss theoretically that proposed generalized estimators are more efficient than Sousa et al. (2010), Gupta et al. (2012) and Koyuncu, Gupta, and Sousa (2014) estimators. Results from a real life application and simulation study are presented to demonstrate the performance of the proposed mean estimators in relation to some of the existing mean estimators.
Model averaging by jackknife criterion for varying-coefficient partially linear modelsHu, Guozhi; Cheng, Weihu; Zeng, Jie
doi: 10.1080/03610926.2019.1580736pmid: N/A
AbstractThis paper is concerned with model averaging procedure for varying-coefficient partially linear models. We proposed a jackknife model averaging method that involves minimizing a leave-one-out cross-validation criterion, and developed a computational shortcut to optimize the cross-validation criterion for weight choice. The resulting model average estimator is shown to be asymptotically optimal in terms of achieving the smallest possible squared error. The simulation studies have provided evidence of the superiority of the proposed procedures. Our approach is further applied to a real data.
Benchmark profile and inferences for joint-exposure quantal data in quantitative risk assessmentKerns, Lucy
doi: 10.1080/03610926.2019.1580740pmid: N/A
AbstractIn risk assessment, it is often desired to make inferences on the minimum dose levels (benchmark doses or BMDs) at which a specific benchmark risk (BMR) is attained. The estimation and inferences of BMDs are well understood in the case of an adverse response to a single-exposure agent. However, the theory of finding BMDs and making inferences on the BMDs is much less developed for cases where the adverse effect of two hazardous agents is studied simultaneously. Deutsch and Piegorsch [2012. Benchmark dose profiles for joint-action quantal data in quantitative risk assessment. Biometrics 68(4):1313–22] proposed a benchmark modeling paradigm in dual exposure setting—adapted from the single-exposure setting—and developed a strategy for conducting full benchmark analysis with joint-action quantal data, and they further extended the proposed benchmark paradigm to continuous response outcomes [Deutsch, R. C., and W. W. Piegorsch. 2013. Benchmark dose profiles for joint-action continuous data in quantitative risk assessment. Biometrical Journal 55(5):741–54]. In their 2012 article, Deutsch and Piegorsch worked exclusively with the complementary log link for modeling the risk with quantal data. The focus of the current paper is on the logit link; particularly, we consider an Abbott-adjusted [A method of computing the effectiveness of an insecticide. Journal of Economic Entomology 18(2):265–7] log-logistic model for the analysis of quantal data with nonzero background response. We discuss the estimation of the benchmark profile (BMP)—a collection of benchmark points which induce the prespecified BMR—and propose different methods for building benchmark inferences in studies involving two hazardous agents. We perform Monte Carlo simulation studies to evaluate the characteristics of the confidence limits. An example is given to illustrate the use of the proposed methods.