Clinical and Experimental Dermatology

Sarkar, Rashmi; Sil, Abheek; Soni, Sonika; Das, Anupam

doi: 10.1093/ced/llag001pmid: 41483007

Leprosy is a disease of great antiquity that affects individuals of all ages and backgrounds. Despite consolidated global control efforts, the disease has remained endemic in many regional pockets. In this regard, particular epidemiological attention is paid to childhood infection as it highlights disease transmission. Children are especially susceptible to leprosy due to their immature immunity and potential intrafamilial contact sources. This provides an opportunity to detect the index case, usually within the family. Leprosy in children has the potential to cause progressive physical deformity, with consequent psychosocial impacts on both the child and the caregiver family. This narrative review focuses on leprosy in the paediatric population, encompassing epidemiological, clinical, diagnostic and therapeutic aspects.

Ghosh, Chaitali; Karmakar, Chaitali; Sarkar, Deblina; Goswami, Deep; Roy, Madhurima; Sengupta, Shilpa; Chaudhuri, Surya J; Roy, Sutopa; Dutta, Bhaskar; Das, Anupam; Das, Nilay K; Chatterjee, Mitali

doi: 10.1093/ced/llag010

Das, Anupam; Dutta, Bhaskar; Padovese, Valeska; Hay, Roderick James; Khan, Sidra S

doi: 10.1093/ced/llag034pmid: 41578869

Dermatophytosis is a commonly encountered superficial fungal infection with an affinity for keratin-rich structures, such as skin, hair and nails. The recently emerging recalcitrant dermatophytosis is a recurrent, relapsing, chronic or persistent disease, which has a significant impact on the social, emotional and financial aspects of a patient’s life. Trichophyton indotineae, a newly identified species, has become resistant to conventional therapies, unlike its predecessor. This review highlights the shift of this commonly encountered skin disease from an easily manageable clinical entity to an emerging resistant epidemic. We also discuss why dermatophytosis is being labelled as a ‘designated fungal threat’.

Gupta, Sanjeev; Gupta, Shubhangi; Deokar, Shubham; Manoj, Rohan

doi: 10.1093/ced/llag033pmid: 41604420

Mycetoma is a chronic disease prevalent in tropical regions, marked by painless swelling and sinus discharge. This study discusses the case of a male farmer, emphasizing early diagnosis and management to prevent complications like osteomyelitis. Treatment involved itraconazole, highlighting the importance of accessible healthcare and education in rural areas for effective disease management.