Synthetic Communications

doi: 10.1080/00397918608056339pmid: N/A

Abstract This is a scanned image of the original Editorial Board page(s) for this issue.

Roser, Joachim; Eberbach, Wolfgang

doi: 10.1080/00397918608056340pmid: N/A

Abstract The alkaline cleavage of trimethylsilyl alkynes under PTC conditions is a mild and straightforward alternative to other methods. Applications of the new deprotection technique include the one-pot Darzensdesilylation reaction of trimethylsilyl alkynals without affecting the oxirane ring in the final products.

Hormi, Osmo E. O.

doi: 10.1080/00397918608056341pmid: N/A

Abstract Reaction of enolates of benzoylmalonate and phosphorus oxychloride is studied. The yield of isolated β-chlorobenzylidene malonate is doubled by using tertiary amines for the formation of the enolate of benzoylmalonate instead of starting from alkali salt. The role of trialkylammonium hydrochloride is discussed. Improved synthesis of β-chloroarylidene/alkylidene malonates is described in detail.

Moreno-Mañas, M.; Ortuño, R. M.; Prat, M.; Galán, M. A.

doi: 10.1080/00397918608056342pmid: N/A

Abstract Some allylic alcohols react with aldehydes and triphenylphosphine in a one-pot formal Wittig reaction under Pd° catalysis. The method has been extended to cinnamyl alcohol, 1, 2-methyl-2-propen-1-01, 7, and 3-buten-2-01, 11, and to heterocyclic aldehydes.

Fariña, Francisco; Molina, M. Teresa; Paredes, M. Carmen

doi: 10.1080/00397918608056343pmid: N/A

Abstract Conjugated addition of alcohols to 9-hydroxy-and 9-methoxy-1, 4-anthraquinone, in the presence of a strong acid and an oxidant, affords the 2-alkoxy- and 3-alkoxy-substituted regioisomer, respectively.

Farina, Vittorio

doi: 10.1080/00397918608056344pmid: N/A

Abstract A new procedure for the preparation of 3-iodomethyl cephems and their in situ functionalization to 3′-substituted cephems is reported.

Kraus, George A.; Man, Tim On

doi: 10.1080/00397918608056345pmid: N/A

Abstract The reductive methylation of quinones bearing electron donating groups such as hydroxyl or alkoxyl groups proceeds in good yields. The improved conditions greatly extend the scope of this useful reaction.

Dellaria, Joseph F.; Nordeen, Carl; Swett, Leo R.

doi: 10.1080/00397918608056346pmid: N/A

Abstract Phenolic and thiol esters are prepared efficiently in a facile process which involves heating the desired acyl halide and thiol or phenol as a neat mixture. Distillation after HX (X = Cl or Br) gas evolution ceases provides the title compounds in 75–96% yields.

Ramaiah, Muthyala; Nagabhushan, T. L.

doi: 10.1080/00397918608056347pmid: N/A

Abstract The synthesis of carbacerulenin (2) by way of intramolecular cyclopropanation of a undecatriene system 8 is described.

Nishiyama, Yutaka; Hamanaka, Sawako; Ogawa, Akiya; Murai, Shinji; Sonoda, Noboru

doi: 10.1080/00397918608056348pmid: N/A

Abstract Aliphatic ketones and aldehydes undergo reductive selenation with selenium, carbon monoxide, and water, followed by air oxidation, to give symmetrical diselenides in moderate to high yields (eq 2).