Age-related changes in regional brain volume evaluated by atlas-based methodGonoi, Wataru; Abe, Osamu; Yamasue, Hidenori; Yamada, Haruyasu; Masutani, Yoshitaka; Takao, Hidemasa; Kasai, Kiyoto; Aoki, Shigeki; Ohtomo, Kuni
doi: 10.1007/s00234-009-0641-5pmid: 20033142
The atlas-based method introduced in the present study has advantages over the manually traced ROI method in its objectivity, coverage, and time requirement and has an advantage over the VBM method in its computability of absolute volume. The results are largely in agreement with those reported previously, thereby reconfirming the importance of matching gender and age in analyzing brain disorders.