Journal of Neurophysiology

Giovanni Frighetto, Nicola Cellini

doi: 10.1152/jn.00213.2016pmid: 27146983

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Excitatory synapses at yellow dendritic locations resulted in the largest depolarizations at the soma, while the same synaptic activation at purple locations generated only weak somatic depolarizations. This visualization is surrounded by scatter plots representing the evolutionary optimization: biophysical models optimized across different fitness functions demonstrate tradeoffs between full high-dimensional error (y-axis) and individual error scores (individual x-axes; clockwise order from top left: subthreshold error, instantaneous firing rate error, spike-shape error, average firing rate error). Color based on 5 error percentiles in increasing instantaneous firing-rate error (purple, red, dark orange, light orange, yellow). From Neymotin SA, Suter BA, Dura-Bernal S, Shepherd GMG, Migliore M, Lytton WW. Optimizing computer models of corticospinal neurons to replicate in vitro dynamics. J Neurophysiol ; doi: 10.1152/jn.00570.2016 . Table of Contents Back Matter (PDF) Keywords Active system consolidation conditioning honeybees memory consolidation model organism sleep Article Abstract DISCLOSURES AUTHOR CONTRIBUTIONS ACKNOWLEDGMENTS REFERENCES Info E-letters PDF Alert me when this article is cited Alert me if a correction is posted Email Thank you for your interest in spreading the word on Journal of Neurophysiology. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address. Your Email * Your Name * Send To * Enter multiple addresses on separate lines or separate them with commas. You are going to email the following Sleep and memory consolidation: a common mechanism across species? Message Subject (Your Name) has sent you a message from Journal of Neurophysiology Message Body (Your Name) thought you would like to see the Journal of Neurophysiology web site. Your Personal Message Print Citation Tools Sleep and memory consolidation: a common mechanism across species? Giovanni Frighetto , Nicola Cellini Journal of Neurophysiology Jan 2017, 117 (1) 1-3; DOI: 10.1152/jn.00213.2016 Citation Manager Formats BibTeX Bookends EasyBib EndNote (tagged) EndNote 8 (xml) Medlars Mendeley Papers RefWorks Tagged Ref Manager RIS Zotero Share Sleep and memory consolidation: a common mechanism across species? Giovanni Frighetto , Nicola Cellini Journal of Neurophysiology Jan 2017, 117 (1) 1-3; DOI: 10.1152/jn.00213.2016 Permalink: Copy View Full Page PDF Tweet Widget Facebook Like Google Plus One Reddit CiteULike Mendeley StumbleUpon More in this TOC Section Bursting deep dorsal horn neurons: The pharmacological target for the anti-spastic effects of Zolmitriptan? Elucidating the neural circuitry underlying planning of internally-guided voluntary action Show more Neuro Forum Related Articles Cited By... Most Read Most Cited Theories of pain: from specificity to gate control Reward, Addiction, and Emotion Regulation Systems Associated With Rejection in Love Reward, Motivation, and Emotion Systems Associated With Early-Stage Intense Romantic Love Inaudible High-Frequency Sounds Affect Brain Activity: Hypersonic Effect The organization of the human cerebral cortex estimated by intrinsic functional connectivity More... GA_googleFillSlot("JN_tower_right_160x600"); Navigate Current Issue Articles in Press Archives Feedback Submit Subscribe Personal Alerts More Information About this Journal Information for Authors Submit a Manuscript Press Advertising AuthorChoice Calls for Papers Ethics Policy PubMed Central Policy Reprints and Permissions Institutional Administrators APS Publications News Follow APS Publications on Twitter American Physiological Society Journals Cell Physiology Advances in Physiology Education Comprehensive Physiology Endocrinology and Metabolism Gastrointestinal and Liver Physiology Heart and Circulatory Physiology Journal of Applied Physiology Journal of Neurophysiology Lung Cellular and Molecular Physiology Physiological Genomics Physiological Reviews Physiology Regulatory, Integrative and Comparative Physiology Renal Physiology Physiological Reports Legacy Content APS Select www.physiology.org Copyright © 2017 The American Physiological Society | Print ISSN: 0022-3077 | Online ISSN: 1522-1598

Vincent Jacob, Akinori Mitani, Taro Toyoizumi, Kevin Fox

doi: 10.1152/jn.00289.2016pmid: 27707809

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Intrinsic firing patterns and whisker-evoked synaptic responses of neurons in the rat barrel cortex . J Neurophysiol 81 : 1171 – 1183 , 1999 . OpenUrl Abstract / FREE Full Text View Abstract Previous Next Back to top View this article with LENS What is LENS? About the Cover About the Cover Cover image Cover : Electrophysiological and morphological measurements were obtained simultaneously from a single corticospinal neuron. These data served as constraints on evolutionary optimization, generating a family of corticospinal models. A three-dimensional reconstruction serves as the backbone for a pseudo-color visualization of synaptic efficiency as a function of dendritic location, simulated in a single biophysical model selected from the family of optimal individuals. Excitatory synapses at yellow dendritic locations resulted in the largest depolarizations at the soma, while the same synaptic activation at purple locations generated only weak somatic depolarizations. This visualization is surrounded by scatter plots representing the evolutionary optimization: biophysical models optimized across different fitness functions demonstrate tradeoffs between full high-dimensional error (y-axis) and individual error scores (individual x-axes; clockwise order from top left: subthreshold error, instantaneous firing rate error, spike-shape error, average firing rate error). Color based on 5 error percentiles in increasing instantaneous firing-rate error (purple, red, dark orange, light orange, yellow). From Neymotin SA, Suter BA, Dura-Bernal S, Shepherd GMG, Migliore M, Lytton WW. Optimizing computer models of corticospinal neurons to replicate in vitro dynamics. J Neurophysiol ; doi: 10.1152/jn.00570.2016 . Table of Contents Back Matter (PDF) Keywords cortical circuit conductance cortical column plasticity vibrissa Article Abstract METHODS RESULTS DISCUSSION GRANTS DISCLOSURES AUTHOR CONTRIBUTIONS REFERENCES Figures & Data Info E-letters PDF Alert me when this article is cited Alert me if a correction is posted Email Thank you for your interest in spreading the word on Journal of Neurophysiology. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address. Your Email * Your Name * Send To * Enter multiple addresses on separate lines or separate them with commas. You are going to email the following Whisker row deprivation affects the flow of sensory information through rat barrel cortex Message Subject (Your Name) has sent you a message from Journal of Neurophysiology Message Body (Your Name) thought you would like to see the Journal of Neurophysiology web site. Your Personal Message Print Citation Tools Whisker row deprivation affects the flow of sensory information through rat barrel cortex Vincent Jacob , Akinori Mitani , Taro Toyoizumi , Kevin Fox Journal of Neurophysiology Jan 2017, 117 (1) 4-17; DOI: 10.1152/jn.00289.2016 Citation Manager Formats BibTeX Bookends EasyBib EndNote (tagged) EndNote 8 (xml) Medlars Mendeley Papers RefWorks Tagged Ref Manager RIS Zotero Share Whisker row deprivation affects the flow of sensory information through rat barrel cortex Vincent Jacob , Akinori Mitani , Taro Toyoizumi , Kevin Fox Journal of Neurophysiology Jan 2017, 117 (1) 4-17; DOI: 10.1152/jn.00289.2016 Permalink: Copy View Full Page PDF Tweet Widget Facebook Like Google Plus One Reddit CiteULike Mendeley StumbleUpon More in this TOC Section The relationship between ERP components and EEG spatial complexity in a visual Go/Nogo task Does the sensorimotor system minimize prediction error or select the most likely prediction during object lifting? Innocuous warming enhances peripheral serotonergic itch signaling and evokes enhanced responses in serotonin-responsive dorsal horn neurons in the mouse Show more Research Article Related Articles Cited By... Most Read Most Cited Theories of pain: from specificity to gate control Reward, Addiction, and Emotion Regulation Systems Associated With Rejection in Love Reward, Motivation, and Emotion Systems Associated With Early-Stage Intense Romantic Love Inaudible High-Frequency Sounds Affect Brain Activity: Hypersonic Effect The organization of the human cerebral cortex estimated by intrinsic functional connectivity More... 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Eline Borch Petersen, Malte Wöstmann, Jonas Obleser, Thomas Lunner

doi: 10.1152/jn.00527.2016pmid: 27707813

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OpenUrl CrossRef Medline ↵ Zoefel B , VanRullen R . The role of high-level processes for oscillatory phase entrainment to speech sound . Front Hum Neurosci 9 : 651 , 2015 . OpenUrl View Abstract Previous Next Back to top View this article with LENS What is LENS? About the Cover About the Cover Cover image Cover : Electrophysiological and morphological measurements were obtained simultaneously from a single corticospinal neuron. These data served as constraints on evolutionary optimization, generating a family of corticospinal models. A three-dimensional reconstruction serves as the backbone for a pseudo-color visualization of synaptic efficiency as a function of dendritic location, simulated in a single biophysical model selected from the family of optimal individuals. Excitatory synapses at yellow dendritic locations resulted in the largest depolarizations at the soma, while the same synaptic activation at purple locations generated only weak somatic depolarizations. This visualization is surrounded by scatter plots representing the evolutionary optimization: biophysical models optimized across different fitness functions demonstrate tradeoffs between full high-dimensional error (y-axis) and individual error scores (individual x-axes; clockwise order from top left: subthreshold error, instantaneous firing rate error, spike-shape error, average firing rate error). Color based on 5 error percentiles in increasing instantaneous firing-rate error (purple, red, dark orange, light orange, yellow). From Neymotin SA, Suter BA, Dura-Bernal S, Shepherd GMG, Migliore M, Lytton WW. Optimizing computer models of corticospinal neurons to replicate in vitro dynamics. J Neurophysiol ; doi: 10.1152/jn.00570.2016 . Table of Contents Back Matter (PDF) Keywords hearing loss neural tracking attention speech-onset envelope electroencephalography cross-correlation Article Abstract METHODS RESULTS DISCUSSION GRANTS DISCLOSURES AUTHOR CONTRIBUTIONS ACKNOWLEDGMENTS REFERENCES Figures & Data Info E-letters PDF Alert me when this article is cited Alert me if a correction is posted Email Thank you for your interest in spreading the word on Journal of Neurophysiology. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address. Your Email * Your Name * Send To * Enter multiple addresses on separate lines or separate them with commas. You are going to email the following Neural tracking of attended versus ignored speech is differentially affected by hearing loss Message Subject (Your Name) has sent you a message from Journal of Neurophysiology Message Body (Your Name) thought you would like to see the Journal of Neurophysiology web site. Your Personal Message Print Citation Tools Neural tracking of attended versus ignored speech is differentially affected by hearing loss Eline Borch Petersen , Malte Wöstmann , Jonas Obleser , Thomas Lunner Journal of Neurophysiology Jan 2017, 117 (1) 18-27; DOI: 10.1152/jn.00527.2016 Citation Manager Formats BibTeX Bookends EasyBib EndNote (tagged) EndNote 8 (xml) Medlars Mendeley Papers RefWorks Tagged Ref Manager RIS Zotero Share Neural tracking of attended versus ignored speech is differentially affected by hearing loss Eline Borch Petersen , Malte Wöstmann , Jonas Obleser , Thomas Lunner Journal of Neurophysiology Jan 2017, 117 (1) 18-27; DOI: 10.1152/jn.00527.2016 Permalink: Copy View Full Page PDF Tweet Widget Facebook Like Google Plus One Reddit CiteULike Mendeley StumbleUpon More in this TOC Section The relationship between ERP components and EEG spatial complexity in a visual Go/Nogo task Does the sensorimotor system minimize prediction error or select the most likely prediction during object lifting? Innocuous warming enhances peripheral serotonergic itch signaling and evokes enhanced responses in serotonin-responsive dorsal horn neurons in the mouse Show more Research Article Related Articles Cited By... Most Read Most Cited Theories of pain: from specificity to gate control Reward, Addiction, and Emotion Regulation Systems Associated With Rejection in Love Reward, Motivation, and Emotion Systems Associated With Early-Stage Intense Romantic Love Inaudible High-Frequency Sounds Affect Brain Activity: Hypersonic Effect The organization of the human cerebral cortex estimated by intrinsic functional connectivity More... 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Xia Mao, Xinglong Gu, Wei Lu

doi: 10.1152/jn.00307.2016pmid: 27707810

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These data served as constraints on evolutionary optimization, generating a family of corticospinal models. A three-dimensional reconstruction serves as the backbone for a pseudo-color visualization of synaptic efficiency as a function of dendritic location, simulated in a single biophysical model selected from the family of optimal individuals. Excitatory synapses at yellow dendritic locations resulted in the largest depolarizations at the soma, while the same synaptic activation at purple locations generated only weak somatic depolarizations. This visualization is surrounded by scatter plots representing the evolutionary optimization: biophysical models optimized across different fitness functions demonstrate tradeoffs between full high-dimensional error (y-axis) and individual error scores (individual x-axes; clockwise order from top left: subthreshold error, instantaneous firing rate error, spike-shape error, average firing rate error). Color based on 5 error percentiles in increasing instantaneous firing-rate error (purple, red, dark orange, light orange, yellow). From Neymotin SA, Suter BA, Dura-Bernal S, Shepherd GMG, Migliore M, Lytton WW. Optimizing computer models of corticospinal neurons to replicate in vitro dynamics. J Neurophysiol ; doi: 10.1152/jn.00570.2016 . Table of Contents Back Matter (PDF) Keywords AMPA receptor GSG1L Deactivation desensitization synapse hippocampus outside-out patch Article Abstract MATERIALS AND METHODS RESULTS DISCUSSION GRANTS DISCLOSURES AUTHOR CONTRIBUTIONS ACKNOWLEDGMENTS REFERENCES Figures & Data Info E-letters PDF Alert me when this article is cited Alert me if a correction is posted Email Thank you for your interest in spreading the word on Journal of Neurophysiology. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address. Your Email * Your Name * Send To * Enter multiple addresses on separate lines or separate them with commas. You are going to email the following GSG1L regulates the strength of AMPA receptor-mediated synaptic transmission but not AMPA receptor kinetics in hippocampal dentate granule neurons Message Subject (Your Name) has sent you a message from Journal of Neurophysiology Message Body (Your Name) thought you would like to see the Journal of Neurophysiology web site. Your Personal Message Print Citation Tools GSG1L regulates the strength of AMPA receptor-mediated synaptic transmission but not AMPA receptor kinetics in hippocampal dentate granule neurons Xia Mao , Xinglong Gu , Wei Lu Journal of Neurophysiology Jan 2017, 117 (1) 28-35; DOI: 10.1152/jn.00307.2016 Citation Manager Formats BibTeX Bookends EasyBib EndNote (tagged) EndNote 8 (xml) Medlars Mendeley Papers RefWorks Tagged Ref Manager RIS Zotero Share GSG1L regulates the strength of AMPA receptor-mediated synaptic transmission but not AMPA receptor kinetics in hippocampal dentate granule neurons Xia Mao , Xinglong Gu , Wei Lu Journal of Neurophysiology Jan 2017, 117 (1) 28-35; DOI: 10.1152/jn.00307.2016 Permalink: Copy View Full Page PDF Tweet Widget Facebook Like Google Plus One Reddit CiteULike Mendeley StumbleUpon More in this TOC Section The relationship between ERP components and EEG spatial complexity in a visual Go/Nogo task Does the sensorimotor system minimize prediction error or select the most likely prediction during object lifting? Innocuous warming enhances peripheral serotonergic itch signaling and evokes enhanced responses in serotonin-responsive dorsal horn neurons in the mouse Show more Research Article Related Articles Cited By... Most Read Most Cited Theories of pain: from specificity to gate control Reward, Addiction, and Emotion Regulation Systems Associated With Rejection in Love Reward, Motivation, and Emotion Systems Associated With Early-Stage Intense Romantic Love Inaudible High-Frequency Sounds Affect Brain Activity: Hypersonic Effect The organization of the human cerebral cortex estimated by intrinsic functional connectivity More... GA_googleFillSlot("JN_tower_right_160x600"); Navigate Current Issue Articles in Press Archives Feedback Submit Subscribe Personal Alerts More Information About this Journal Information for Authors Submit a Manuscript Press Advertising AuthorChoice Calls for Papers Ethics Policy PubMed Central Policy Reprints and Permissions Institutional Administrators APS Publications News Follow APS Publications on Twitter American Physiological Society Journals Cell Physiology Advances in Physiology Education Comprehensive Physiology Endocrinology and Metabolism Gastrointestinal and Liver Physiology Heart and Circulatory Physiology Journal of Applied Physiology Journal of Neurophysiology Lung Cellular and Molecular Physiology Physiological Genomics Physiological Reviews Physiology Regulatory, Integrative and Comparative Physiology Renal Physiology Physiological Reports Legacy Content APS Select www.physiology.org Copyright © 2017 The American Physiological Society | Print ISSN: 0022-3077 | Online ISSN: 1522-1598

Raza Naseem Malik, Rachel Cote, Tania Lam

doi: 10.1152/jn.00169.2016pmid: 27733593

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These data served as constraints on evolutionary optimization, generating a family of corticospinal models. A three-dimensional reconstruction serves as the backbone for a pseudo-color visualization of synaptic efficiency as a function of dendritic location, simulated in a single biophysical model selected from the family of optimal individuals. Excitatory synapses at yellow dendritic locations resulted in the largest depolarizations at the soma, while the same synaptic activation at purple locations generated only weak somatic depolarizations. This visualization is surrounded by scatter plots representing the evolutionary optimization: biophysical models optimized across different fitness functions demonstrate tradeoffs between full high-dimensional error (y-axis) and individual error scores (individual x-axes; clockwise order from top left: subthreshold error, instantaneous firing rate error, spike-shape error, average firing rate error). Color based on 5 error percentiles in increasing instantaneous firing-rate error (purple, red, dark orange, light orange, yellow). From Neymotin SA, Suter BA, Dura-Bernal S, Shepherd GMG, Migliore M, Lytton WW. Optimizing computer models of corticospinal neurons to replicate in vitro dynamics. J Neurophysiol ; doi: 10.1152/jn.00570.2016 . Table of Contents Back Matter (PDF) Keywords proprioception gaze behavior Obstacle crossing spinal cord injury Functional mobility Article Abstract METHODS RESULTS DISCUSSION GRANTS DISCLOSURES AUTHOR CONTRIBUTIONS ACKNOWLEDGMENTS REFERENCES Figures & Data Info E-letters PDF Alert me when this article is cited Alert me if a correction is posted Email Thank you for your interest in spreading the word on Journal of Neurophysiology. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address. 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Your Personal Message Print Citation Tools Sensorimotor integration of vision and proprioception for obstacle crossing in ambulatory individuals with spinal cord injury Raza Naseem Malik , Rachel Cote , Tania Lam Journal of Neurophysiology Jan 2017, 117 (1) 36-46; DOI: 10.1152/jn.00169.2016 Citation Manager Formats BibTeX Bookends EasyBib EndNote (tagged) EndNote 8 (xml) Medlars Mendeley Papers RefWorks Tagged Ref Manager RIS Zotero Share Sensorimotor integration of vision and proprioception for obstacle crossing in ambulatory individuals with spinal cord injury Raza Naseem Malik , Rachel Cote , Tania Lam Journal of Neurophysiology Jan 2017, 117 (1) 36-46; DOI: 10.1152/jn.00169.2016 Permalink: Copy View Full Page PDF Tweet Widget Facebook Like Google Plus One Reddit CiteULike Mendeley StumbleUpon More in this TOC Section The relationship between ERP components and EEG spatial complexity in a visual Go/Nogo task Does the sensorimotor system minimize prediction error or select the most likely prediction during object lifting? Innocuous warming enhances peripheral serotonergic itch signaling and evokes enhanced responses in serotonin-responsive dorsal horn neurons in the mouse Show more Research Article Related Articles Cited By... Most Read Most Cited Theories of pain: from specificity to gate control Reward, Addiction, and Emotion Regulation Systems Associated With Rejection in Love Reward, Motivation, and Emotion Systems Associated With Early-Stage Intense Romantic Love Inaudible High-Frequency Sounds Affect Brain Activity: Hypersonic Effect The organization of the human cerebral cortex estimated by intrinsic functional connectivity More... 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Maike Vollmer, Ralph E. Beitel, Christoph E. Schreiner, Patricia A. Leake

doi: 10.1152/jn.00392.2016pmid: 27733594

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About the Cover About the Cover Cover image Cover : Electrophysiological and morphological measurements were obtained simultaneously from a single corticospinal neuron. These data served as constraints on evolutionary optimization, generating a family of corticospinal models. A three-dimensional reconstruction serves as the backbone for a pseudo-color visualization of synaptic efficiency as a function of dendritic location, simulated in a single biophysical model selected from the family of optimal individuals. Excitatory synapses at yellow dendritic locations resulted in the largest depolarizations at the soma, while the same synaptic activation at purple locations generated only weak somatic depolarizations. This visualization is surrounded by scatter plots representing the evolutionary optimization: biophysical models optimized across different fitness functions demonstrate tradeoffs between full high-dimensional error (y-axis) and individual error scores (individual x-axes; clockwise order from top left: subthreshold error, instantaneous firing rate error, spike-shape error, average firing rate error). Color based on 5 error percentiles in increasing instantaneous firing-rate error (purple, red, dark orange, light orange, yellow). From Neymotin SA, Suter BA, Dura-Bernal S, Shepherd GMG, Migliore M, Lytton WW. Optimizing computer models of corticospinal neurons to replicate in vitro dynamics. J Neurophysiol ; doi: 10.1152/jn.00570.2016 . Table of Contents Back Matter (PDF) Keywords cochlear implant deafness inferior colliculus primary auditory cortex neuroplasticity temporal processing Article Abstract METHODS RESULTS DISCUSSION ENDNOTE GRANTS DISCLOSURES AUTHOR CONTRIBUTIONS ACKNOWLEDGMENTS REFERENCES Figures & Data Info E-letters PDF Alert me when this article is cited Alert me if a correction is posted Email Thank you for your interest in spreading the word on Journal of Neurophysiology. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address. Your Email * Your Name * Send To * Enter multiple addresses on separate lines or separate them with commas. You are going to email the following Passive stimulation and behavioral training differentially transform temporal processing in the inferior colliculus and primary auditory cortex Message Subject (Your Name) has sent you a message from Journal of Neurophysiology Message Body (Your Name) thought you would like to see the Journal of Neurophysiology web site. Your Personal Message Print Citation Tools Passive stimulation and behavioral training differentially transform temporal processing in the inferior colliculus and primary auditory cortex Maike Vollmer , Ralph E. Beitel , Christoph E. Schreiner , Patricia A. Leake Journal of Neurophysiology Jan 2017, 117 (1) 47-64; DOI: 10.1152/jn.00392.2016 Citation Manager Formats BibTeX Bookends EasyBib EndNote (tagged) EndNote 8 (xml) Medlars Mendeley Papers RefWorks Tagged Ref Manager RIS Zotero Share Passive stimulation and behavioral training differentially transform temporal processing in the inferior colliculus and primary auditory cortex Maike Vollmer , Ralph E. Beitel , Christoph E. Schreiner , Patricia A. Leake Journal of Neurophysiology Jan 2017, 117 (1) 47-64; DOI: 10.1152/jn.00392.2016 Permalink: Copy View Full Page PDF Tweet Widget Facebook Like Google Plus One Reddit CiteULike Mendeley StumbleUpon More in this TOC Section The relationship between ERP components and EEG spatial complexity in a visual Go/Nogo task Does the sensorimotor system minimize prediction error or select the most likely prediction during object lifting? Innocuous warming enhances peripheral serotonergic itch signaling and evokes enhanced responses in serotonin-responsive dorsal horn neurons in the mouse Show more Research Article Related Articles Cited By... Most Read Most Cited Theories of pain: from specificity to gate control Reward, Addiction, and Emotion Regulation Systems Associated With Rejection in Love Reward, Motivation, and Emotion Systems Associated With Early-Stage Intense Romantic Love Inaudible High-Frequency Sounds Affect Brain Activity: Hypersonic Effect The organization of the human cerebral cortex estimated by intrinsic functional connectivity More... 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Kévin Marche, Paul Apicella

doi: 10.1152/jn.00566.2016pmid: 27733597

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A three-dimensional reconstruction serves as the backbone for a pseudo-color visualization of synaptic efficiency as a function of dendritic location, simulated in a single biophysical model selected from the family of optimal individuals. Excitatory synapses at yellow dendritic locations resulted in the largest depolarizations at the soma, while the same synaptic activation at purple locations generated only weak somatic depolarizations. This visualization is surrounded by scatter plots representing the evolutionary optimization: biophysical models optimized across different fitness functions demonstrate tradeoffs between full high-dimensional error (y-axis) and individual error scores (individual x-axes; clockwise order from top left: subthreshold error, instantaneous firing rate error, spike-shape error, average firing rate error). Color based on 5 error percentiles in increasing instantaneous firing-rate error (purple, red, dark orange, light orange, yellow). From Neymotin SA, Suter BA, Dura-Bernal S, Shepherd GMG, Migliore M, Lytton WW. Optimizing computer models of corticospinal neurons to replicate in vitro dynamics. J Neurophysiol ; doi: 10.1152/jn.00570.2016 . Table of Contents Back Matter (PDF) Keywords basal ganglia movement initiation motor preparation nonhuman primate Article Abstract MATERIALS AND METHODS RESULTS DISCUSSION GRANTS DISCLOSURES AUTHOR CONTRIBUTIONS ACKNOWLEDGMENTS REFERENCES Figures & Data Info E-letters PDF Alert me when this article is cited Alert me if a correction is posted Email Thank you for your interest in spreading the word on Journal of Neurophysiology. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address. Your Email * Your Name * Send To * Enter multiple addresses on separate lines or separate them with commas. You are going to email the following Changes in activity of fast-spiking interneurons of the monkey striatum during reaching at a visual target Message Subject (Your Name) has sent you a message from Journal of Neurophysiology Message Body (Your Name) thought you would like to see the Journal of Neurophysiology web site. Your Personal Message Print Citation Tools Changes in activity of fast-spiking interneurons of the monkey striatum during reaching at a visual target Kévin Marche , Paul Apicella Journal of Neurophysiology Jan 2017, 117 (1) 65-78; DOI: 10.1152/jn.00566.2016 Citation Manager Formats BibTeX Bookends EasyBib EndNote (tagged) EndNote 8 (xml) Medlars Mendeley Papers RefWorks Tagged Ref Manager RIS Zotero Share Changes in activity of fast-spiking interneurons of the monkey striatum during reaching at a visual target Kévin Marche , Paul Apicella Journal of Neurophysiology Jan 2017, 117 (1) 65-78; DOI: 10.1152/jn.00566.2016 Permalink: Copy View Full Page PDF Tweet Widget Facebook Like Google Plus One Reddit CiteULike Mendeley StumbleUpon More in this TOC Section The relationship between ERP components and EEG spatial complexity in a visual Go/Nogo task Does the sensorimotor system minimize prediction error or select the most likely prediction during object lifting? Innocuous warming enhances peripheral serotonergic itch signaling and evokes enhanced responses in serotonin-responsive dorsal horn neurons in the mouse Show more Research Article Related Articles Cited By... Most Read Most Cited Theories of pain: from specificity to gate control Reward, Addiction, and Emotion Regulation Systems Associated With Rejection in Love Reward, Motivation, and Emotion Systems Associated With Early-Stage Intense Romantic Love Inaudible High-Frequency Sounds Affect Brain Activity: Hypersonic Effect The organization of the human cerebral cortex estimated by intrinsic functional connectivity More... 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Tarkeshwar Singh, Julius Fridriksson, Christopher M. Perry, Sarah C. Tryon, Angela Ross, Stacy Fritz, Troy M. Herter

doi: 10.1152/jn.00561.2016pmid: 27733596

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About the Cover About the Cover Cover image Cover : Electrophysiological and morphological measurements were obtained simultaneously from a single corticospinal neuron. These data served as constraints on evolutionary optimization, generating a family of corticospinal models. A three-dimensional reconstruction serves as the backbone for a pseudo-color visualization of synaptic efficiency as a function of dendritic location, simulated in a single biophysical model selected from the family of optimal individuals. Excitatory synapses at yellow dendritic locations resulted in the largest depolarizations at the soma, while the same synaptic activation at purple locations generated only weak somatic depolarizations. This visualization is surrounded by scatter plots representing the evolutionary optimization: biophysical models optimized across different fitness functions demonstrate tradeoffs between full high-dimensional error (y-axis) and individual error scores (individual x-axes; clockwise order from top left: subthreshold error, instantaneous firing rate error, spike-shape error, average firing rate error). Color based on 5 error percentiles in increasing instantaneous firing-rate error (purple, red, dark orange, light orange, yellow). From Neymotin SA, Suter BA, Dura-Bernal S, Shepherd GMG, Migliore M, Lytton WW. Optimizing computer models of corticospinal neurons to replicate in vitro dynamics. J Neurophysiol ; doi: 10.1152/jn.00570.2016 . Table of Contents Back Matter (PDF) Keywords visual search computational model saccades stroke visuomotor Article Abstract MATERIALS AND METHODS RESULTS DISCUSSION GRANTS DISCLOSURES AUTHOR CONTRIBUTIONS REFERENCES Figures & Data Info E-letters PDF Alert me when this article is cited Alert me if a correction is posted Email Thank you for your interest in spreading the word on Journal of Neurophysiology. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address. Your Email * Your Name * Send To * Enter multiple addresses on separate lines or separate them with commas. You are going to email the following A novel computational model to probe visual search deficits during motor performance Message Subject (Your Name) has sent you a message from Journal of Neurophysiology Message Body (Your Name) thought you would like to see the Journal of Neurophysiology web site. Your Personal Message Print Citation Tools A novel computational model to probe visual search deficits during motor performance Tarkeshwar Singh , Julius Fridriksson , Christopher M. Perry , Sarah C. Tryon , Angela Ross , Stacy Fritz , Troy M. Herter Journal of Neurophysiology Jan 2017, 117 (1) 79-92; DOI: 10.1152/jn.00561.2016 Citation Manager Formats BibTeX Bookends EasyBib EndNote (tagged) EndNote 8 (xml) Medlars Mendeley Papers RefWorks Tagged Ref Manager RIS Zotero Share A novel computational model to probe visual search deficits during motor performance Tarkeshwar Singh , Julius Fridriksson , Christopher M. Perry , Sarah C. Tryon , Angela Ross , Stacy Fritz , Troy M. Herter Journal of Neurophysiology Jan 2017, 117 (1) 79-92; DOI: 10.1152/jn.00561.2016 Permalink: Copy View Full Page PDF Tweet Widget Facebook Like Google Plus One Reddit CiteULike Mendeley StumbleUpon More in this TOC Section Modelling microelectrode biosensors: free-flow calibration can substantially underestimate tissue concentrations Revealing unobserved factors underlying cortical activity using a rectified latent variable model applied to neural population recordings Show more Innovative Methodology Related Articles Cited By... Most Read Most Cited Theories of pain: from specificity to gate control Reward, Addiction, and Emotion Regulation Systems Associated With Rejection in Love Reward, Motivation, and Emotion Systems Associated With Early-Stage Intense Romantic Love Inaudible High-Frequency Sounds Affect Brain Activity: Hypersonic Effect The organization of the human cerebral cortex estimated by intrinsic functional connectivity More... 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Edyta K. Bichler, Courtney C. Elder, Paul S. García

doi: 10.1152/jn.00134.2016pmid: 27733592

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About the Cover About the Cover Cover image Cover : Electrophysiological and morphological measurements were obtained simultaneously from a single corticospinal neuron. These data served as constraints on evolutionary optimization, generating a family of corticospinal models. A three-dimensional reconstruction serves as the backbone for a pseudo-color visualization of synaptic efficiency as a function of dendritic location, simulated in a single biophysical model selected from the family of optimal individuals. Excitatory synapses at yellow dendritic locations resulted in the largest depolarizations at the soma, while the same synaptic activation at purple locations generated only weak somatic depolarizations. This visualization is surrounded by scatter plots representing the evolutionary optimization: biophysical models optimized across different fitness functions demonstrate tradeoffs between full high-dimensional error (y-axis) and individual error scores (individual x-axes; clockwise order from top left: subthreshold error, instantaneous firing rate error, spike-shape error, average firing rate error). Color based on 5 error percentiles in increasing instantaneous firing-rate error (purple, red, dark orange, light orange, yellow). From Neymotin SA, Suter BA, Dura-Bernal S, Shepherd GMG, Migliore M, Lytton WW. Optimizing computer models of corticospinal neurons to replicate in vitro dynamics. J Neurophysiol ; doi: 10.1152/jn.00570.2016 . Table of Contents Back Matter (PDF) Keywords clarithromycin hippocampus neuronal excitability GABAA receptor Article Abstract METHODS RESULTS DISCUSSION GRANTS DISCLOSURES AUTHOR CONTRIBUTIONS ACKNOWLEDGMENTS REFERENCES Figures & Data Info E-letters PDF Alert me when this article is cited Alert me if a correction is posted Email Thank you for your interest in spreading the word on Journal of Neurophysiology. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address. Your Email * Your Name * Send To * Enter multiple addresses on separate lines or separate them with commas. You are going to email the following Clarithromycin increases neuronal excitability in CA3 pyramidal neurons through a reduction in GABAergic signaling Message Subject (Your Name) has sent you a message from Journal of Neurophysiology Message Body (Your Name) thought you would like to see the Journal of Neurophysiology web site. Your Personal Message Print Citation Tools Clarithromycin increases neuronal excitability in CA3 pyramidal neurons through a reduction in GABAergic signaling Edyta K. Bichler , Courtney C. Elder , Paul S. García Journal of Neurophysiology Jan 2017, 117 (1) 93-103; DOI: 10.1152/jn.00134.2016 Citation Manager Formats BibTeX Bookends EasyBib EndNote (tagged) EndNote 8 (xml) Medlars Mendeley Papers RefWorks Tagged Ref Manager RIS Zotero Share Clarithromycin increases neuronal excitability in CA3 pyramidal neurons through a reduction in GABAergic signaling Edyta K. Bichler , Courtney C. Elder , Paul S. García Journal of Neurophysiology Jan 2017, 117 (1) 93-103; DOI: 10.1152/jn.00134.2016 Permalink: Copy View Full Page PDF Tweet Widget Facebook Like Google Plus One Reddit CiteULike Mendeley StumbleUpon More in this TOC Section The relationship between ERP components and EEG spatial complexity in a visual Go/Nogo task Does the sensorimotor system minimize prediction error or select the most likely prediction during object lifting? Innocuous warming enhances peripheral serotonergic itch signaling and evokes enhanced responses in serotonin-responsive dorsal horn neurons in the mouse Show more Research Article Related Articles Cited By... Most Read Most Cited Theories of pain: from specificity to gate control Reward, Addiction, and Emotion Regulation Systems Associated With Rejection in Love Reward, Motivation, and Emotion Systems Associated With Early-Stage Intense Romantic Love Inaudible High-Frequency Sounds Affect Brain Activity: Hypersonic Effect The organization of the human cerebral cortex estimated by intrinsic functional connectivity More... GA_googleFillSlot("JN_tower_right_160x600"); Navigate Current Issue Articles in Press Archives Feedback Submit Subscribe Personal Alerts More Information About this Journal Information for Authors Submit a Manuscript Press Advertising AuthorChoice Calls for Papers Ethics Policy PubMed Central Policy Reprints and Permissions Institutional Administrators APS Publications News Follow APS Publications on Twitter American Physiological Society Journals Cell Physiology Advances in Physiology Education Comprehensive Physiology Endocrinology and Metabolism Gastrointestinal and Liver Physiology Heart and Circulatory Physiology Journal of Applied Physiology Journal of Neurophysiology Lung Cellular and Molecular Physiology Physiological Genomics Physiological Reviews Physiology Regulatory, Integrative and Comparative Physiology Renal Physiology Physiological Reports Legacy Content APS Select www.physiology.org Copyright © 2017 The American Physiological Society | Print ISSN: 0022-3077 | Online ISSN: 1522-1598

N. Apurva Ratan Murty, S. P. Arun

doi: 10.1152/jn.00551.2016pmid: 27733595

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OpenUrl Abstract / FREE Full Text View Abstract Next Back to top View this article with LENS What is LENS? About the Cover About the Cover Cover image Cover : Electrophysiological and morphological measurements were obtained simultaneously from a single corticospinal neuron. These data served as constraints on evolutionary optimization, generating a family of corticospinal models. A three-dimensional reconstruction serves as the backbone for a pseudo-color visualization of synaptic efficiency as a function of dendritic location, simulated in a single biophysical model selected from the family of optimal individuals. Excitatory synapses at yellow dendritic locations resulted in the largest depolarizations at the soma, while the same synaptic activation at purple locations generated only weak somatic depolarizations. This visualization is surrounded by scatter plots representing the evolutionary optimization: biophysical models optimized across different fitness functions demonstrate tradeoffs between full high-dimensional error (y-axis) and individual error scores (individual x-axes; clockwise order from top left: subthreshold error, instantaneous firing rate error, spike-shape error, average firing rate error). Color based on 5 error percentiles in increasing instantaneous firing-rate error (purple, red, dark orange, light orange, yellow). From Neymotin SA, Suter BA, Dura-Bernal S, Shepherd GMG, Migliore M, Lytton WW. Optimizing computer models of corticospinal neurons to replicate in vitro dynamics. J Neurophysiol ; doi: 10.1152/jn.00570.2016 . Table of Contents Back Matter (PDF) Keywords 3-D vision object perception object recognition inferior temporal cortex Article Abstract METHODS RESULTS DISCUSSION GRANTS DISCLOSURES AUTHOR CONTRIBUTIONS REFERENCES Figures & Data Info E-letters PDF Alert me when this article is cited Alert me if a correction is posted Email Thank you for your interest in spreading the word on Journal of Neurophysiology. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address. Your Email * Your Name * Send To * Enter multiple addresses on separate lines or separate them with commas. You are going to email the following Seeing a straight line on a curved surface: decoupling of patterns from surfaces by single IT neurons Message Subject (Your Name) has sent you a message from Journal of Neurophysiology Message Body (Your Name) thought you would like to see the Journal of Neurophysiology web site. Your Personal Message Print Citation Tools Seeing a straight line on a curved surface: decoupling of patterns from surfaces by single IT neurons N. Apurva Ratan Murty , S. P. Arun Journal of Neurophysiology Jan 2017, 117 (1) 104-116; DOI: 10.1152/jn.00551.2016 Citation Manager Formats BibTeX Bookends EasyBib EndNote (tagged) EndNote 8 (xml) Medlars Mendeley Papers RefWorks Tagged Ref Manager RIS Zotero Share Seeing a straight line on a curved surface: decoupling of patterns from surfaces by single IT neurons N. Apurva Ratan Murty , S. P. Arun Journal of Neurophysiology Jan 2017, 117 (1) 104-116; DOI: 10.1152/jn.00551.2016 Permalink: Copy View Full Page PDF Tweet Widget Facebook Like Google Plus One Reddit CiteULike Mendeley StumbleUpon More in this TOC Section The relationship between ERP components and EEG spatial complexity in a visual Go/Nogo task Does the sensorimotor system minimize prediction error or select the most likely prediction during object lifting? Innocuous warming enhances peripheral serotonergic itch signaling and evokes enhanced responses in serotonin-responsive dorsal horn neurons in the mouse Show more Research Article Related Articles Cited By... 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