Diabetologia

Rubin, R.; Gaussoin, S.; Peyrot, M.; DiLillo, V.; Miller, K.; Wadden, T.; West, D.; Wing, R.; Knowler, W.

doi: 10.1007/s00125-010-1765-1pmid: 20422396

Among Look AHEAD participants, depression symptoms or ADM use on entry to the study were each independently associated with a wide range of CVD risk factors. Future research should assess the temporal dynamics of the relationships of depression symptoms and ADM use with CVD risk factors. Trial registration Clinicaltrials.gov NCT00017953 Funding This study is funded by the National Institutes of Health with additional support from the Centers for Disease Control and Prevention.

Borg, R.; Kuenen, J.; Carstensen, B.; Zheng, H.; Nathan, D.; Heine, R.; Nerup, J.; Borch-Johnsen, K.; Witte, D.

doi: 10.1007/s00125-010-1741-9pmid: 20396998

Even though the non-diabetic individuals monitored in the ADAG study were selected on the basis of a very low level of baseline FPG, 10% of these spent a considerable amount of time at glucose levels considered to be ‘prediabetic’ or indicating IGT. This highlights the fact that exposure to moderately elevated glucose levels remains under-appreciated when individuals are classified on the basis of isolated glucose measurements.

Owen, C.; Nightingale, C.; Rudnicka, A.; Sattar, N.; Cook, D.; Ekelund, U.; Whincup, P.

doi: 10.1007/s00125-010-1781-1pmid: 20454952

Objectively measured physical activity correlates at least as well with obesity and cardiometabolic risk factors in South Asian and African-Caribbean children as in white European children, suggesting that efforts to increase activity levels in such groups would have equally beneficial effects.

Shimoda, M.; Chen, S.; Noguchi, H.; Matsumoto, S.; Grayburn, P.

doi: 10.1007/s00125-010-1745-5pmid: 20405100

Delivery of VEGF gene to host liver using UTMD promoted islet revascularisation after islet transplantation and improved the restoration of euglycaemia.

Phielix, E.; Meex, R.; Moonen-Kornips, E.; Hesselink, M.; Schrauwen, P.

doi: 10.1007/s00125-010-1764-2pmid: 20422397

We confirmed lower intrinsic mitochondrial function in diabetic patients compared with control individuals. Diabetic patients increased their mitochondrial content to the same extent as control individuals and had similar intrinsic mitochondrial function, which occurred parallel with improved insulin sensitivity.

Schernthaner, G.; Barnett, A.; Betteridge, D.; Carmena, R.; Ceriello, A.; Charbonnel, B.; Hanefeld, M.; Lehmann, R.; Malecki, M.; Nesto, R.; Pirags, V.; Scheen, A.; Seufert, J.; Sjöholm, Å.; Tsatsoulis, A.;