Clinical Chemistry

Boutwell, Joseph, H

doi: 10.1093/clinchem/3.4.205pmid: N/A

Abstract 1. The sources of turbidity in directly nesslerized blood and urine filtrates have been discussed and a new method of nesslerization has been presented which eliminates turbidities. The new procedure has been compared in a quantitative manner with several methods. 2. A procedure for the determination of blood and urine urea and for urine ammonia has been presented, incorporating the new nesslerization technic. This content is only available as a PDF. © 1957 The American Association for Clinical Chemistry This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model)

Balikov,, Bernard;Castello, Robert, A;Lozano, Eloy, R

doi: 10.1093/clinchem/3.4.217pmid: N/A

Abstract The pattern of peptiduria in serious burns has been presented. This pattern has been found to vary, depending upon whether the patient's condition deteriorates or improves. The changes in this pattern resulting from various complications often seen in an extensive burn have been noted. Evidence has been presented supporting the theory of the endogenous origin of urinary peptides. This content is only available as a PDF. © 1957 The American Association for Clinical Chemistry This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model)

Galloway, Leora, S;Nielson, Patricia, W;Wilcox, Ethelwyn, B;Lantz, Edith, M

doi: 10.1093/clinchem/3.4.226pmid: N/A

Abstract A micro method for cholesterol determination adapted from the macro method of Sperry and Webb is described with comparisons of results obtained by the two methods. In general, the two methods gave similar results for free and total cholesterol. This content is only available as a PDF. © 1957 The American Association for Clinical Chemistry This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model)

Carpenter, K, J;Gotsis,, A;Hegsted, D, M

doi: 10.1093/clinchem/3.4.233pmid: N/A

Abstract A method has been described for the estimation of total cholesterol in 0.02ml. of serum without the need for micro apparatus. It involves the measurement of the fluorescence developed after the addition of sulfuric acid to a solution of cholesterol in a mixture of 1,1,2-trichloroethane and acetic anhydride(1). The results obtained with both human and rat sera have been in good agreement with those obtained with a standard colorimetric method(2), and the standard deviation for an estimation carried through in duplicate, owing to error within the method, has been ±4-5 mg. per 100 ml. under routine conditions. This content is only available as a PDF. © 1957 The American Association for Clinical Chemistry This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model)

Gray,, Irving;Young, James, G

doi: 10.1093/clinchem/3.4.239pmid: N/A

Abstract The Weil-Malherbe and Bone method for the analysis of the plasma concentration of epinephrine and norepinephrine has been modified and used to determine the plasma concentration in normal humans. The average value for epinephrine in the plasma of men in this series was less than 0.11 µg./L.; for women it was 0.47 µg./L. The average value for norepinephrine in men was 3.4 µg./L. and in women it was 4.9 µg./L. The differences between the concentrations in men and women are significant, P<0.001 and P<0.01 for epinephrine and norepinephrine, respectively. Evidence has been presented to indicate the specificity of the method. Reproducibility and recovery data have been given. This content is only available as a PDF. © 1957 The American Association for Clinical Chemistry This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model)

Sethna,, Shirley;Tsao, M, U

doi: 10.1093/clinchem/3.4.249pmid: N/A

Abstract Results are given of simultaneous determinations of protein on 17 pooled cerebrospinal fluids (see Table 1) and 22 diluted sera and plasma specimens (see Table 2) by the following methods: micro-Kjeldahl; Johnston-Gibson tyrosine equivalence method; sulfosalicylic acid method; trichloroacetic acid method at 37° and two biuret methods. The micro-Kjeldahl method was used as the standard for comparison. This content is only available as a PDF. © 1957 The American Association for Clinical Chemistry This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model)

Papadopoulou, Daphne, B

doi: 10.1093/clinchem/3.4.257pmid: N/A

Abstract 1. The partition of inorganic and total sulfate and total and neutral sulfur has been estimated in 10 normal men and 27 cancer patients. 2. The excretion of inorganic and total sulfate was found to be decreased and the neutral sulfur fraction increased in cancer patients more than in the normal subjects. 3. From the data above, it is suggested that there may be a decrease in the rate of the intracellular oxidation substances in the body of cancer patients. This content is only available as a PDF. © 1957 The American Association for Clinical Chemistry This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model)

Meites,, Samuel

doi: 10.1093/clinchem/3.4.263pmid: N/A

Abstract 1. A method for the extraction of non-α-amino organic acids from urine based on the work of Isherwood is described. 2. The relative position of elution of 42 biologically significant acids from silica gel columns is demonstrated. A number of important acids known to be present in urine are not eluted. 3. The partition chromatography of urinary organic acids reveals the presence of 9 peaks, of which 4 are known to be acetic, formic, lactic, and citric acids. A fifth peak contains glycolic and oxalic acids. 4. The aromatic acids are eluted principally in the first peak, which contains hippuric acids as a major constituent. 5. A minimum of two unknown organic acids are constantly present in relatively large concentrations in urine. Two additional acids appear frequently. This content is only available as a PDF. © 1957 The American Association for Clinical Chemistry This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model)

Vella,, F;Lugg, J W, H

doi: 10.1093/clinchem/3.4.270pmid: N/A

Article PDF first page preview Close This content is only available as a PDF. © 1957 The American Association for Clinical Chemistry This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model)

doi: 10.1093/clinchem/3.4.273pmid: N/A

Article PDF first page preview Close This content is only available as a PDF. © 1957 The American Association for Clinical Chemistry This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model)