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Did you mean: transcription regulation of the heme oxygenase 1 gene by pyrrolidine

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    Transcriptional regulation of the heme oxygenase 1 gene by pyrrolidine dithiocarbamate.

    Hartsfield, C. L.; Alam, J.; Choi, A. M.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology MEDLINE Abstracts – Dec 1, 1998
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    17-Hydroxy-jolkinolide B, a diterpenoid from Euphorbia fischeriana , inhibits inflammatory mediators but activates heme oxygenase-1 expression in lipopolysaccharide-stimulated murine macrophages

    Uto, Takuhiro; Qin, Guo-Wei; Morinaga, Osamu; Shoyama, Yukihiro
    Follow International Immunopharmacology , Volume 12 (1) Elsevier – Jan 1, 2012

    effects were caused by suppression of MAPK phosphorylation and NF-κB activation. Furthermore, we demonstrated that HJB strongly induced heme oxygenase-1 (HO-1) protein and mRNA expressions. These findings ...

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    An IκBα phosphorylation inhibitor induces heme oxygenase-1(HO-1) expression through the activation of reactive oxygen species (ROS)–Nrf2–ARE signaling and ROS–PI3K/Akt signaling in an NF-κB

    Min, Kyoung-jin; Lee, Jung Tae; Joe, Eun-hye; Kwon, Taeg Kyu
    Follow Cellular Signalling , Volume 23 (9) Elsevier – Sep 1, 2011

    oxygenase-1 (HO-1), tightly regulate ROS levels within cells. Here, we show that Bay 11-7082 (Bay) increased HO-1 mRNA and protein expression in human colon cancer HT29 cells. Bay induced translocation of NF ...

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    Activation of heat shock factor 1 plays a role in pyrrolidine dithiocarbamate-mediated expression of the co-chaperone BAG3

    Song, Shaoming; Kole, Sutapa; Precht, Patricia; Pazin, Michael J.; Bernier, Michel
    Follow The International Journal of Biochemistry & Cell Biology , Volume 42 (11) Elsevier – Nov 1, 2010

    70 (Hsp70) and several other genes, including heme oxygenase-1, in response to PDTC, which provides adaptive protection of stressed cells and tissues from various pathophysiological conditions ...

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    Transforming growth factor-β1 stimulates heme oxygenase-1 expression via the PI3K/Akt and NF-κB pathways in human lung epithelial cells

    Lin, Chen-Chun; Chiang, Ling-Ling; Lin, Chien-Huang; Shih, Chung-Hung; Liao, Yi-Ting; Hsu, Ming-Jen; Chen, Bing-Chang
    Follow European Journal of Pharmacology , Volume 560 (2) Elsevier – Apr 10, 2007

    A previous report showed that transforming growth factor-β1 (TGF-β1) can induce heme oxygenase-1 (HO-1) expression, attenuate cellular injury, and maintain tissue homeostasis. In this study, we ...

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    More Like This F5msL4jLzE Rentable

    N ‐(4‐hydroxyphenyl)retinamide induces apoptosis in human retinal pigment epithelial cells: Retinoic acid receptors regulate apoptosis, reactive oxygen species generation, and the expression of heme

    Samuel, William; Kutty, R. Krishnan; Nagineni, Sahrudaya; Vijayasarathy, Camasamudram; Chandraratna, Roshantha A.S.; Wiggert, Barbara
    Follow Journal of Cellular Physiology , Volume 209 (3) Wiley – Dec 1, 2006

    , the increase in the expression of heme oxygenase‐1 (HO‐1), a stress response protein, and the growth arrest and DNA damage‐inducible transcription factor 153 (Gadd153) in response to the ROS generation were also ...

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    Effect of pyrrolidine dithiocarbamate on hepatic vascular stress gene expression during ischemia and reperfusion

    Lee, Chan-Ho; Kim, Sung-Ho; Lee, Sun-Mee
    Follow European Journal of Pharmacology , Volume 595 (1) Elsevier – Oct 24, 2008

    , there is no information in vivo on the transcription factor-mediated alterations in the vasoregulatory genes in ischemic livers.Therefore, this study examined whether or not 1) pyrrolidine dithiocarbamate modulates ...

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    Negative regulation of osteoblastogenesis through downregulation of runt‐related transcription factor‐2 in osteoblastic MC3T3‐E1 cells with stable overexpression of the cystine/glutamate antiporter

    Uno, Kyosuke; Takarada, Takeshi; Takarada‐Iemata, Mika; Nakamura, Yukari; Fujita, Hiroyuki; Hinoi, Eiichi; Yoneda, Yukio
    Follow Journal of Cellular Physiology , Volume 226 (11) Wiley – Nov 1, 2011

    bovine serum; GAPDH, glyceraldehyde‐3‐phosphate dehydrogenase; Glu, glutamate; GSH, reduced glutathione; HO‐1, heme oxygenase‐1; L ‐PDC, L ‐trans‐pyrrolidine‐2,4‐dicarboxylic acid; MTT, 3‐(4,5 ...

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    More Like This gryvfmTxbd Rentable

    Guggulsterone induces heme oxygenase-1 expression through activation of Nrf2 in human mammary epithelial cells: PTEN as a putative target

    Almazari, Inas; Park, Jong-Min; Park, Sin-Aye; Suh, Jin-Young; Na, Hye-Kyung; Cha, Young-Nam; Surh, Young-Joon
    Follow Carcinogenesis , Volume 33 (2) Oxford University Press

    ). In this study, the effects of both isomers on expression of the cytoprotective enzyme heme oxygenase-1 (HO-1) were evaluated in human mammary epithelial (MCF10A) cells. NF-E2-related factor 2 (Nrf2) is considered ...

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    More Like This 9r0SBnPdQH Rentable

    Hypoxia inducible factor-1 modulates hemin-induced IL-8 secretion in microvascular endothelium

    Natarajan, Ramesh; Fisher, Bernard J.; Fowler, Alpha A.
    Follow Microvascular Research , Volume 73 (3) Elsevier – May 1, 2007

    report was the finding that hypoxia inducible factor-1 (HIF-1), a powerful transcription factor mediating tissue responses to hypoxia, potently regulated hemin-induced IL-8 secretion in human MVEC ...

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