Did you mean: transcription profiling reveals a critical role for tyrosine
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with these findings, total RNA sequencing reveals widespread co-transcriptional splicing in the human brain ( Ameur et al., 2011 ). Similarly, measurements of complete and incomplete splicing rates through the analysis ...
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. Transcriptional profiling reveals the full consequences of PKD2 loss and maps in detail the selective, but critical, function for PKD2 in signalling by α/β mature TCR complexes in peripheral T-cells.Key words ...
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evidences supporting the critical role of the c-Met pathway in various human cancers, no c-Met inhibitors have been approved for treating cancer patients [7] . Currently, some of c-Met targeted inhibitors ...
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described as a negative regulator of STAT3α, gene knockout studies have revealed that both forms play critical roles. We have expressed STAT3α and STAT3β at comparable levels to facilitate a direct comparison ...
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). However, oncogenic activation can more widely and radically impact cell physiology through downstream effects on gene expression. Common instances of this phenomenon occur when transcription factors ...
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events involved in oocyte maturation have proven amenable to biochemical and genetic analyses, which have revealed an important role for cyclic nucleotide and dedicated cell cycle protein kinases during ...
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Poster Sessions ejc supplements 8, no. 5 (2010) 83154 386 The role of DUSP1 in angiogenesis and lung cancer metastases V. Moncho1 , I. Ibanez de Caceres2 , E. Bandres3 , B. Martinez-Poveda4 , ~ ´ I ...
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and the impact of therapeutic approaches on the septic state.Genome-wide microarray technology has been already applied to reveal transcriptional changes in liver following the CLP treatment [4–6] . However ...
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damage [22] .The oncogenic role of STAT3 in non-small cell lung carcinoma (NSCLC) has been postulated. High-density tissue arrays profiling revealed STAT3 activation (increased levels of phosphorylated ...