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Did you mean: the role of architectural transcription factors in cytokines gene
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The role of architectural transcription factors in cytokine gene transcription M. F. Shannon * , L. S. Coles † , J. Attema * and P. Diamond † * Division of Biochemistry and Molecular Biology, John ...
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and fibrosis ( Steib et al., 2007 ).Nuclear factor kappaB (NF-κB) comprises a family of inducible transcription factors consisting of p65 and p50 subunits of Rel protein family that serves as important ...
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-dependent manner, facilitating differential transcriptional control of genes ( 101 ). Functional Roles of Sox Factors Are Dependent on Spatial, Dose, and Temporal Context Sox factors are expressed ...
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the function of mediators of the inflammatory process including IL-8, ICAM-1, and the MHC factor. HBx also activates two transcription factors, NF-κB and NFAT, implicated in the regulation of cytokine expression ...
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, cytokines have dual roles in bone homeostasis, with different effects depending on the type of immune response [5-7] .Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine mainly ...
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mechanism remains unclear. Here, we report that AMPK inhibits transforming growth factor (TGF)‐β‐induced fibrogenic property of HSCs by regulating transcriptional coactivator p300. We treated human (LX‐2 ...
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-regulatory sequence located approximately 100–200 bp upstream of the transcription start site of each MHC-II gene. The sequence consists of the W/S/Z, X1, X2, and Y box elements [ 2 ]. NF-Y (nuclear factor-Y ...
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that cohesin also forms long-range chromosomal cis -interactions and may regulate gene expression in association with CTCF , mediator or tissue-specific transcription factors . Human cohesinopathies ...
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of the transcription pathway in Drosophila development and NF-κB (nuclear factor κB) activation in the mammalian immune system prompted investigations that revealed the immune role of Toll in Drosophila and spurred ...
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to the role of chromatin in allowing transcription factor access to appropriate genes. 1 Introduction Cytokines are an important group of proteins that function as intercellular communicators ...
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