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for: the function of activity regulated genes in the nervous system
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The Function of Activity-Regulated Genes in the Nervous System
Loebrich, Sven; Nedivi, Elly
Follow Physiological Reviews , Volume 89 (4): 1079
The American Physiological Society – Oct 1, 2009to external and internal stimuli. We then review the identification of “plasticity genes” regulated by changes in the levels of electrical activity, and how elucidating their cellular functions has revealed ...
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Ghrelin-mediated appetite regulation in the central nervous system
Kirsz, Katarzyna; Zieba, Dorota A.
Follow Peptides , Volume 32 (11)
Elsevier – Nov 1, 2011Highlights ► Ghrelin is a gut hormone and neuropeptide which acts in CNS on the hypothalamus. ► Best-known biological function of ghrelin is the regulation of appetite. ► The activity of ghrelin ...
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Progesterone as a regulator of phosphorylation in the central nervous system
Amorim, Miguel A.R.; Guerra-Araiza, Christian; Garcia-Segura, Luis M.
Follow Hormone Molecular Biology and Clinical Investigation , Volume 4 (3)
de Gruyter – Dec 1, 2010to Akt activation, whereas PI3K inactivation leads to Akt inhibition (51â53). After activation, Akt can phosphorylate a variety of substrates involved in regulation of cellular key functions (54, 55 ...
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Protective effects and mechanisms of sirtuins in the nervous system
Zhang, Feng; Wang, Suping; Gan, Li; Vosler, Peter S.; Gao, Yanqin; Zigmond, Michael J.; Chen, Jun
Follow Progress in Neurobiology , Volume 95 (3)
Elsevier – Nov 1, 2011a regulatory function on its target proteins, and those regulations include subcellular translocation and altered enzymatic activity of the target proteins ( Verger et al., 2003; Zschoernig and Mahlknecht, 2008 ...
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MicroRNA in central nervous system trauma and degenerative disorders
Liu, Nai-Kui; Xu, Xiao-Ming
Follow Physiological Genomics , Volume 43 (10): 571
The American Physiological Society – May 1, 2011that miRNAs are highly expressed in the central nervous system (CNS) including the brain and spinal cord. Although we are currently in the initial stages of understanding how this novel class of gene regulators ...
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Mechanisms of specificity in neuronal activity-regulated gene transcription
Lyons, Michelle R.; West, Anne E.
Follow Progress in Neurobiology , Volume 94 (3)
Elsevier – Aug 1, 2011activity-dependent manner.3 Transcription factors regulated by neuronal activity Activity-regulated signaling pathways modulate gene transcription by altering the function, localization ...
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The expression and localization of Prune2 mRNA in the central nervous system
Li, Shimo; Itoh, Masanori; Ohta, Kazunori; Ueda, Masashi; Mizuno, Akihito; Ohta, Eri; Hida, Yoko; Wang, Miao-xing; Takeuchi, Kazunori; Nakagawa, Toshiyuki
Follow Neuroscience Letters , Volume 503 (3)
Elsevier – Oct 10, 2011stromal tumors [24] ; prune homolog 2 ( Drosophila ) ( PRUNE2 ) has been identified as a susceptibility gene for Alzheimer's disease by a Genome-Wide Association study [23] ; and the up-regulation ...
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Regulation of non-coding RNA networks in the nervous system—What's the REST of the story?
Qureshi, Irfan A.; Mehler, Mark F.
Follow Neuroscience Letters , Volume 466 (2)
Elsevier – Dec 4, 2009silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) and non-coding RNAs (ncRNAs) are emerging as key regulators that seem to orchestrate almost every aspect of nervous system ...
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Leptin and the Central Nervous System Control of Glucose Metabolism
Morton, Gregory J.; Schwartz, Michael W.
Follow Physiological Reviews , Volume 91 (2): 389
The American Physiological Society – Apr 1, 2011Abstract The regulation of body fat stores and blood glucose levels is critical for survival. This review highlights growing evidence that leptin action in the central nervous system plays a key role ...
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Long non-coding RNAs in nervous system function and disease
Qureshi, Irfan A.; Mattick, John S.; Mehler, Mark F.
Follow Brain Research , Volume 1338
Elsevier – Jun 18, 2010Central nervous system (CNS) development, homeostasis, stress responses, and plasticity are all mediated by epigenetic mechanisms that modulate gene expression and promote selective deployment ...
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