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, and collagens, which are key to cartilage structure and function.—Tan, K., Duquette, M., Joachimiak, A., Lawler, J. The crystal structure of the signature domain of cartilage oligomeric matrix protein ...
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in red. (E) The THBS-2 EGF1-EGF3 crystal structure from the signature domain of THBS-2 (PDB code: 1YO8) is colored as follows: disulfide bonds (grey CPK sticks), calcium-binding residues (CPK sticks ...
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to a second subclass of pentameric proteins. All thrombospondins share a highly conserved C-terminal signature domain. These domains of TSP1 and TSP2 have been crystallized, and Carlson et al. review ...
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in the pentameric coiled-coil domain of cartilage oligomerization matrix protein (COMPcc) and the tetrameric right-handed coiled coil of Staphylothermus marinus (RHCC) has led us and others to look for therapeutic ...
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multiple N ‐acetyllactosamine units present on cell surface glycoproteins and glycolipids ( 2 ). Crystal structure of most galectins has been determined showing that these proteins contain at least one ...
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