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for: sphingosine 1 phosphate induces development of functionally mature
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Sphingosine-1-phosphate induces development of functionally mature chymase-expressing human mast cells from hematopoietic progenitors
Price, Megan M.; Kapitonov, Dmitri; Allegood, Jeremy; Milstien, Sheldon; Oskeritzian, Carole A.; Spiegel, Sarah
Follow The FASEB Journal , Volume 23 (10): 3506
Fed of American Socs for Experimental Biology – Oct 1, 2009in the development of mature human MCs.—Price, M. M., Kapitonov, D., Allegood, J., Milstien, S., Oskeritzian, C. A., Spiegel, S. Sphingosine-1-phosphate induces development of functionally mature chymase-expressing ...
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Export and functions of sphingosine-1-phosphate
Kim, Roger H.; Takabe, Kazuaki; Milstien, Sheldon; Spiegel, Sarah
Follow Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids , Volume 1791 (7)
Elsevier – Jul 1, 2009The sphingolipid metabolite, sphingosine-1-phosphate (S1P), has emerged as a critical player in a number of fundamental biological processes and is important in cancer, angiogenesis, wound healing ...
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Sphingosine 1-phosphate chemical biology
Lynch, Kevin R.; Macdonald, Timothy L.
Follow Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids , Volume 1781 (9)
Elsevier – Sep 1, 2008A dozen years ago, the term ‘S1P’ (sphingosine 1-phosphate) was not in the lexicons of scientific literature databases. By early 2008, this query term retrieved well over 1000 citations from PubMed ...
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An update on sphingosine-1-phosphate and other sphingolipid mediators
Fyrst, Henrik; Saba, Julie D
Follow Nature Chemical Biology , Volume 6 (7)
Nature Publishing Group (NPG) – Jul 1, 2010biology. Sphingosine-1-phosphate is essential for mammalian brain and cardiac development and for maturation of the systemic circulatory system and lymphatics. In addition, sphingosine-1-phosphate ...
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Sequential delivery of vascular endothelial growth factor and sphingosine 1-phosphate for angiogenesis
Tengood, Jillian E.; Kovach, Kyle M.; Vescovi, Patrick E.; Russell, Alan J.; Little, Steven R.
Follow Biomaterials , Volume 31 (30)
Elsevier – Oct 1, 2010of angiogenesis, such as endothelial cell migration and proliferation [5] , vascular network maturation [7] and induce a proangiogenic phenotype in endothelial cells [8] . Of these factors, VEGF and sphingosine 1 ...
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Shaping of terminal megakaryocyte differentiation and proplatelet development by sphingosine-1-phosphate receptor S1P4
Golfier, Sven; Kondo, Shinichi; Schulze, Tobias; Takeuchi, Tomomi; Vassileva, Galya; Achtman, Ariel H.; Gräler, Markus H.; Abbondanzo, Susan J.; Wiekowski, Maria; Kremmer, Elisabeth; Endo, Yasuhisa; Lira, Sergio A.; Bacon, Kevin B.; Lipp, Martin
Follow The FASEB Journal , Volume 24 (12): 4701
Fed of American Socs for Experimental Biology – Dec 1, 2010, E., Endo, Y., Lira, S. A., Bacon, K. B., Lipp, M. Shaping of terminal megakaryocyte differentiation and proplatelet development by sphingosine-1-phosphate receptor S1P 4 . platelets lysophospholipids ...
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Relevance and potential of sphingosine-1-phosphate in vascular inflammatory disease
van der Giet, Markus; Tölle, Markus; Kleuser, Burkhard
Follow Biological Chemistry , Volume 389 (11)
de Gruyter – Nov 1, 2008. Recently, sphingolipid sphingosine-1-phosphate (S1P) was identified as a crucial molecule with potent anti-inflammatory properties. Indeed, S1P activates various G protein-coupled receptors, namely S1P1–S1P5 ...
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Cell-surface residence of sphingosine 1-phosphate receptor 1 on lymphocytes determines lymphocyte egress kinetics
Thangada, Shobha; Khanna, Kamal M.; Blaho, Victoria A.; Oo, Myat Lin; Im, Dong-Soon; Guo, Caiying; Lefrancois, Leo; Hla, Timothy
Follow The Journal of Experimental Medicine , Volume 207 (7): 1475
Rockefeller University Press – Jul 5, 2010The sphingosine 1-phosphate receptor 1 (S1P 1 ) promotes lymphocyte egress from lymphoid organs. Previous work showed that agonist-induced internalization of this G protein–coupled receptor ...
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Sphingosine-1-phosphate signaling and biological activities in the cardiovascular system
Takuwa, Yoh; Okamoto, Yasuo; Yoshioka, Kazuaki; Takuwa, Noriko
Follow Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids , Volume 1781 (9)
Elsevier – Sep 1, 2008to cardiovascular diseases and cancer. 1 IntroductionSphingosine-1-phosphate (S1P) is a lysophospholipid mediator circulating in blood, which induces a wide variety of biological responses in a diversity ...
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The roles of sphingosine-1-phosphate in asthma
Jolly, Puneet S; Rosenfeldt, Hans M; Milstien, Sheldon; Spiegel, Sarah
Follow Molecular Immunology , Volume 38 (16)
Elsevier – Sep 1, 2002addition to the repertoire of FcεRI-mediated signaling events is the activation of sphingosine kinase leading to the generation of the potent sphingolipid mediator, sphingosine-1-phosphate (S1P) from ...
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