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). The key role in this specific binding is believed to be played by the sequence CCAAT or its complementary Y-box core sequence ATTGG. Further studies showed a wider YB protein specificity for DNA binding ...
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a base pair step is kinked or a region of the minor groove is narrow). Based on the >1500 structures of protein-DNA complexes now available in the Protein Data Bank, we argue that individual DNA-binding ...
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. 22,43–47 Most of these MEF2-interacting proteins have been shown to bind to the MADS-box/MEF2 region.Given the important roles of the MADS-box/MEF2 domain in DNA-binding and protein–protein ...
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are accommodated, and the role and disposition of the acidic tail, are unclear.Many nuclear HMG-box-containing DNA-binding proteins have been identified. Some, like HMGB1, are relatively abundant and bind without ...
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Untranslated region Introduction The SBP-domain proteins play signiWcant roles in diverse aspects of plant development; this has become evident in recent years and has been documented in an increasing number ...
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as PowerPoint Slide Figure 1. Schematic representation of mammalian mtDNA. The double-stranded circular mammalian mtDNA molecule of ∼16.5 kb contains a single longer noncoding region, the displacement loop (D ...
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., 1994 ; Skehel and Bartsch, 1994 ). Y-box binding proteins were shown to bind to both double-stranded and single-stranded DNA and also to mRNA (for review, see Wolffe et al., 1992 ; Wolffe, 1994 ...
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method to evaluate sequences around RefSeq genes for conserved CArG boxes. Utilizing a predetermined phastCons threshold score, we identified 8,252 strand-specific CArGs within an 8 kb window around ...
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in the variable region is 10 6 times higher than in the rest of the genome. The heavy chain region of Ig genes then undergo CSR, due to double strand breaks caused by DNA repair proteins, to switch between ...