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for: reward processing by the opioid system in the brain
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Reward Processing by the Opioid System in the Brain
Le Merrer, Julie; Becker, Jérôme A. J.; Befort, Katia; Kieffer, Brigitte L.
Follow Physiological Reviews , Volume 89 (4): 1379
The American Physiological Society – Oct 1, 2009Abstract The opioid system consists of three receptors, mu, delta, and kappa, which are activated by endogenous opioid peptides processed from three protein precursors, proopiomelanocortin ...
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kappa-Opioid receptor signaling and brain reward function
Bruijnzeel, Adrie W.
Follow Brain Research Reviews , Volume 62 (1)
Elsevier – Dec 11, 2009(i.e., the kappa-opioid receptor) play a critical role in regulating the state of the brain reward system by modulating dopamine release in the striatum ( Di Chiara and Imperato, 1988b; Maisonneuve et al ...
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Differential involvement of the opioid receptor antagonist naloxone in motivational and hedonic aspects of reward
Schneider, Miriam; Heise, Verena; Spanagel, Rainer
Follow Behavioural Brain Research , Volume 208 (2)
Elsevier – Apr 2, 2010effective in suppressing the hedonic than motivational aspects of reward, further supporting the involvement of the endogenous opioid system in the mediation of hedonic properties of food reward. 1 ...
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Endogenous opioids and reward
Van Ree, Jan M; Niesink, Raymond J.M; Van Wolfswinkel, Leo; Ramsey, Nick F; Kornet, Marleen (L.) M.W; Van Furth, Wouter R; Vanderschuren, Louk J.M.J; Gerrits, Mirjam A.F.M; Van den Berg, Caroline L
Follow European Journal of Pharmacology , Volume 405 (1)
Elsevier – Sep 29, 2000The discovery of endogenous opioids has markedly influenced the research on the biology of addiction and reward brain processes. Evidence has been presented that these brain substances modulate brain ...
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Emerging, reemerging, and forgotten brain areas of the reward circuit: Notes from the 2010 Motivational Neural Networks conference
McGinty, Vincent B.; Hayden, Benjamin Y.; Heilbronner, Sarah R.; Dumont, Eric C.; Graves, Steven M.; Mirrione, Martine M.; du Hoffmann, Johann; Sartor, Gregory C.; España, Rodrigo A.; Millan, E. Zayra; DiFeliceantonio, Alexandra G.; Marchant, Nathan J.; Napier, T. Celeste; Root, David H.; Borgland, Stephanie L.; Treadway, Michael T.; Floresco, Stan B.; McGinty, Jacqueline F.; Haber, Suzanne
Follow Behavioural Brain Research , Volume 225 (1)
Elsevier – Nov 20, 2011Highlights ► The 2010 Motivational Neuronal Networks conference took place on April 24–27. ► Discussions focused on understudied brain regions involved in reward and motivation. ► Topics included ...
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The endogenous opioid system: A common substrate in drug addiction
Trigo, José Manuel; Martin-García, Elena; Berrendero, Fernando; Robledo, Patricia; Maldonado, Rafael
Follow Drug and Alcohol Dependence , Volume 108 (3)
Elsevier – May 1, 2010Drug addiction is a chronic brain disorder leading to complex adaptive changes within the brain reward circuits that involve several neurotransmitters. One of the neurochemical systems that plays ...
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The placebo-reward hypothesis: dopamine and the placebo effect
de la Fuente-Fernández, Raúl
Follow Parkinsonism & Related Disorders , Volume 15
Elsevier – Dec 1, 2009. In fact, recent evidence suggests that the release of dopamine in the ventral striatum likely triggers the activation of the endogenous opioid system in placebo analgesia. The placebo-reward hypothesis also ...
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Nicotine withdrawal and κ-opioid receptors
Michael, McCarthy; Hailing, Zhang; Norton, Neff; Maria, Hadjiconstantinou
Follow Psychopharmacology , Volume 210 (2)
Springer Journals – Jun 1, 2010accumbens Introduction A growing body of experimental evidence supports the view that the endogenous opioid system might play a role in the addictive properties of nicotine. Indeed, acute or chronic ...
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β-Endorphin and drug-induced reward and reinforcement
Roth-Deri, Ilana; Green-Sadan, Tamar; Yadid, Gal
Follow Progress in Neurobiology , Volume 86 (1)
Elsevier – Sep 1, 2008in the process of drug-seeking behavior is discussed. 1 IntroductionInvolvement of the opioid system in drug-induced reward and reinforcement has been intensively investigated over the past few ...
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Involvement of p38/NF-κB signaling pathway in the nucleus accumbens in the rewarding effects of morphine in rats
Zhang, Xueqin; Cui, Yue; Jing, Jin; Cui, Yu; Xin, Wenjun; Liu, Xianguo
Follow Behavioural Brain Research , Volume 218 (1)
Elsevier – Mar 17, 2011] . The changes in structure and function of the brain's reward circuitry, including the ventral tegmental area (VTA) and the nucleus accumbens (NAc), are involved in the acquisition of CPP [4,5] . For example ...
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