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RAGE: therapeutic target and biomarker of the inflammatory response—the evidence mounts
Ramasamy, Ravichandran; Yan, Shi Fang; Schmidt, Ann Marie
Follow Journal of Leukocyte Biology , Volume 86 (3): 505
Fed of American Socs for Experimental Biology – Sep 1, 2009, in addition to being a potential therapeutic target in chronic disease, monitoring of plasma sRAGE levels may provide a novel biomarker platform for tracking chronic inflammatory diseases, their severity ...
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Symposium Abstracts
Follow Clinical Chemistry and Laboratory Medicine , Volume 49 (s1)
de Gruyter – May 1, 2011, prognosis or monitoring therapeutic response. Methods. A number of mass spectrometry-based cancer biomarker discovery strategies have been employed. These strategies could be broadly grouped into two ...
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The endogenous Toll-like receptor 4 agonist S100A8/S100A9 (calprotectin) as innate amplifier of infection, autoimmunity, and cancer
Ehrchen, Jan M.; Sunderkötter, Cord; Foell, Dirk; Vogl, Thomas; Roth, Johannes
Follow Journal of Leukocyte Biology , Volume 86 (3): 557
Fed of American Socs for Experimental Biology – Sep 1, 2009The innate immune system is crucial for initiation and amplification of inflammatory responses. During this process, phagocytes are activated by PAMPs that are recognized by PRRs. Phagocytes are also ...
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Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging
Salminen, Antero; Huuskonen, Jari; Ojala, Johanna; Kauppinen, Anu; Kaarniranta, Kai; Suuronen, Tiina
Follow Ageing Research Reviews , Volume 7 (2)
Elsevier – Apr 1, 2008of aging in budding yeast and Caenorhabditis elegans models, regulate the efficiency of NF-kB signaling and the level of inflammatory responses. We will review the role of innate immunity signaling ...
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Cardiac Function and Heart Failure
Follow Journal of the American College of Cardiology , Volume 51 (10)
Elsevier – Mar 11, 2008peptides, supporting the role of ST2 in the myocardial-specific inflammatory response to stretch/injury. 9:00 a.m. 1002-19 Genetic Determinants of Cardiac Contractility: A Genome-Wide Association Study ...
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Vascular Disease, Hypertension and Prevention
Follow Journal of the American College of Cardiology , Volume 51 (10)
Elsevier – Mar 11, 200840, 80, 160mg or placebo once daily for 12 weeks. Blood samples were analyzed for Lp-PLA2 activity, inflammatory and platelet biomarkers. Results: At baseline, LDL-c was 68 ± 22 mg/dL. Plasma Lp-PLA2 ...
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Speakers' abstracts
Follow Journal of Perinatal Medicine , Volume 35
de Gruyter – Sep 1, 2007, an exaggerated inflammatory response, and intestinal barrier damage, culminating in mucosal edema, haemorrhage and necrosis. Feeding practices may influence the risk of developing NEC: increment in feeding volumes ...
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Cytokines in Atherosclerosis: Pathogenic and Regulatory Pathways
Tedgui, Alain; Mallat, Ziad
Follow Physiological Reviews , Volume 86 (2): 515
The American Physiological Society – Apr 1, 2006of the mechanisms of atherosclerosis provided evidence that the immunoinflammatory response in atherosclerosis is modulated by regulatory pathways, in which the two anti-inflammatory cytokines interleukin-10 ...
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Congress of Clinical Chemistry and Laboratory Medicine, Annual Congress of the Society of Clinical Chemistry and Laboratory Medicine (DGKL) in association with The Austrian Society for Laboratory Medicine and Clinical Chemistry, The Swiss Society for Clinical Chemistry (SGKC), The German Association of Technical Assistants in Medicine (dvta), Mannheim, Germany, October 1st - 4th, 2006
Follow Clinical Chemistry and Laboratory Medicine , Volume 44 (9)
de Gruyter – Sep 1, 2006cytokines together with metabolic markers should prove a better indicator of the inflammatory state of the patient. Further studies will show whether the use of biomarkers will enable us to reduce morbidity ...
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Abstracts Accepted for Poster Presentations
Follow Annals of Surgical Oncology , Volume 12 (1)
Springer Journals – Feb 1, 2005it an ideal target for the enhancement of the cellular immune response to malignancy. Effective p53 directed immunotherapy will require breaking tolerance to p53. One effective method of overcoming tolerance ...
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