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Oxidative modifications of S100 proteins: functional regulation by redox
Lim, Su Yin; Raftery, Mark J.; Goyette, Jesse; Hsu, Kenneth; Geczy, Carolyn L.
Follow Journal of Leukocyte Biology , Volume 86 (3): 577
Fed of American Socs for Experimental Biology – Sep 1, 2009modifications, particularly generated by oxidation, of several S100 proteins and some effects of these on intracellular and extracellular functions. We focus on gene regulation of S100A8 and S100A9 by ROS ...
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Direct inhibitory and indirect stimulatory effects of RAGE ligand S100 on sRANKL‐induced osteoclastogenesis
Yoshida, Tomohiko; Flegler, Ayanna; Kozlov, Andrew; Stern, Paula H.
Follow Journal of Cellular Biochemistry , Volume 107 (5)
Wiley – Jul 15, 2009Diabetes results in increased fracture risk, and advance glycation endproducts (AGEs) have been implicated in this pathophysiology. S100 proteins are ligands for the receptor of AGEs (RAGE ...
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Copper-mediated cross-linking of S100A4, but not of S100A2, results in proinflammatory effects in melanoma cells
Haase-Kohn, Cathleen; Wolf, Susann; Lenk, Jens; Pietzsch, Jens
Follow Biochemical and Biophysical Research Communications , Volume 413 (3)
Elsevier – Sep 30, 2011S100 proteins, e.g., by modulating the affinity for Ca 2+ and/or other protein targets [8] . It is increasingly evident that oxidative modification of cysteine residues and cross-linking of S100 proteins ...
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Thioredoxin interacting protein (TXNIP) induces inflammation through chromatin modification in retinal capillary endothelial cells under diabetic conditions
Perrone, Lorena; Devi, Takhellambam S.; Hosoya, Ken‐ichi; Terasaki, Tetsuya; Singh, Lalit P.
Follow Journal of Cellular Physiology , Volume 221 (1)
Wiley – Oct 1, 2009, diabetes, and neurodegenerative diseases. RAGE ligands up‐regulate RAGE expression itself, further enhancing local cellular response (Schmidt et al., 2000 ). RAGE ligands include AGEs, S100/calgranulins ...
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Changes in proteomics profile during maturation of marrow‐derived dendritic cells treated with oxidized low‐density lipoprotein
Ge, Junhua; Yan, Hui; Li, Shan; Nie, Wencheng; Dong, Kan; Zhang, Li; Zhu, Weiguo; Fan, Fangyan; Zhu, Jianhua
Follow PROTEOMICS , Volume 11 (10)
Wiley – Apr 8, 2011metabolism, oxidative stress, molecular chaperones and cytoskeletal rearrangement. Several of these proteins are involved in the process of atherosclerosis, such as cathepsins S, G, D, and Z, S100 (S100 ...
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Aberrant regulation and modification of heat shock factor 1 in senescent human diploid fibroblasts
Lee, Yoon Kwang; Liu, Diana J.; Lu, Jiebo; Chen, Kuang Yu; Liu, Alice Y.‐C.
Follow Journal of Cellular Biochemistry , Volume 106 (2)
Wiley – Jan 20, 2009as a function of age, and this was attributable to a change in the regulation of HSF1 as the abundance of HSF1 protein and mRNA was unaffected. HSF1 was primarily cytosolic in young cells maintained at 37°C ...
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Modulation of sarcoplasmic reticulum Ca2+ release in skeletal muscle expressing ryanodine receptor impaired in regulation by calmodulin and S100A1
Yamaguchi, Naohiro; Prosser, Benjamin L.; Ghassemi, Farshid; Xu, Le; Pasek, Daniel A.; Eu, Jerry P.; Hernández-Ochoa, Erick O.; Cannon, Brian R.; Wilder, Paul T.; Lovering, Richard M.; Weber, David; Melzer, Werner; Schneider, Martin F.; Meissner, Gerhard
Follow AJP - Cell Physiology , Volume 300 (5): C998
The American Physiological Society – May 1, 2011+ binding protein family that regulates SR Ca 2+ release and mitochondrial function in many tissues including cardiac and skeletal muscle ( 11 , 46 ). S100A1 bound to several RyR1 fragments and activated ...
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Multiple levels of regulation determine the role of the receptor for AGE (RAGE) as common soil in inflammation, immune responses and diabetes mellitus and its complications
A., Bierhaus; P., Nawroth
Follow Diabetologia , Volume 52 (11)
Springer Journals – Nov 1, 2009immunity . . . Review . S100 Abbreviations ADAM10 A disintegrin and metalloprotease 10 ALE Advanced lipoxidation end-products AOPP Advanced oxidation protein products CDC42 Cell division cycle 42-protein CML ...
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Advanced glycation end products and its receptor (RAGE) are increased in patients with COPD
Wu, Lian; Ma, Li; Nicholson, Louise F.B.; Black, Peter N.
Follow Respiratory Medicine , Volume 105 (3)
Elsevier – Mar 1, 2011Advanced Glycation End products (AGEs) are the products of nonenzymatic glycation and oxidation of proteins and lipids. Formation of AGEs is increased in response to hyperglycaemia, reactive oxygen ...
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Ubiquitination and SUMOylation of annexin A1 and helicase activity
Hirata, Fusao; Thibodeau, Lisa M.; Hirata, Aiko
Follow Biochimica et Biophysica Acta (BBA) - General Subjects , Volume 1800 (9)
Elsevier – Sep 1, 2010as well as Ks, acceptors for ubiquitination that regulates localization and functions of proteins, we investigated SUMOylation and ubiquitination of annexin A1. 1 IntroductionAnnexin A1 ...
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