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with model lipid membranes, the use of NMR techniques provided atomic-resolution insights in terms of structure, membrane orientation and mechanisms [18,19] . The outer membrane of Gram-negative organisms ...
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-inflammatory effect and molecular mechanisms underlying the anti-inflammatory activity of CHE, we used experimentally induced mice endotoxic shock moled and lipopolysaccharide (LPS)-induced murine peritoneal ...
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inflammation and provide novel information for the anti‐inflammation mechanism. J. Cell. Biochem. 114: 1020–1028, 2013. © 2012 Wiley Periodicals, Inc. Lipopolysaccharide (LPS), known as endotoxin ...
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fever and shock in a mammalian host. Foremost among the inducers was endotoxin [lipopolysaccharide (LPS)], represented in most gram-negative bacteria (17). Widely known for its ability to induce septic ...
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bring us within striking distance of the development and validation of novel treatment strategies. Herein we first summarize the molecular components of the mammalian stress-regulated MAPK pathways ...
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of HMGB1 reduces the extent of TLR4-signaling and bacterial translocation suggest a role for HMGB1 in mediating these effects. These findings provide new insights into the molecular mechanisms that mediate ...
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in a variety of biochemical and cellular functions, providing molecular insights into the pathogenesis of TSS. Administration of bortezomib, a clinically approved proteasome inhibitor capable of blocking NF-κB ...
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of different diseases such as type I diabetes and septic shock. The purpose of this review is to give a short overview of the current knowledge about PARP-1 and its functional and biochemical interactions ...
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role in EC proliferation induced by C5b-9, and this is in part mediated through regulation of cell cycle specific genes. A NOVEL MECHANISM FOR COMPLEMENT ACTIVATION ON THE SURFACE OF B CELLS FOLLOWING ...