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for: ion channels in sperm physiology
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Calcium Signaling Through CatSper Channels in Mammalian Fertilization
Ren, Dejian; Xia, Jingsheng
Follow Physiology , Volume 25 (3): 165
The American Physiological Society – Jun 1, 2010channel with physiological importance: 1 ) the protein is detectable in sperm, ideally with knockout sperm as a negative control for antibody specificity; 2 ) the ion channel current generated ...
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Heads or tails? Structural events and molecular mechanisms that promote mammalian sperm acrosomal exocytosis and motility
Buffone, Mariano G.; Ijiri, Takashi W.; Cao, Wenlei; Merdiushev, Tanya; Aghajanian, Haig K.; Gerton, George L.
Follow Molecular Reproduction & Development , Volume 79 (1)
Wiley – Oct 26, 2011.Glycolysis and ATP Like all cells, sperm require the energy of ATP to power cell motility, acrosomal exocytosis, and membrane functions such as ion pumps and channels. With an absence ...
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Calcium Channels in the Development, Maturation, and Function of Spermatozoa
Darszon, Alberto; Nishigaki, Takuya; Beltran, Carmen; Treviño, Claudia L.
Follow Physiological Reviews , Volume 91 (4): 1305
The American Physiological Society – Oct 1, 2011). The fundamental importance of ion channels, particularly those for Ca 2+ , for sperm physiology and fertilization has been consolidated in the last 10 years due to significant advances in the tools available ...
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Recombinant human ZP3-induced sperm acrosome reaction: Evidence for the involvement of T- and L-type voltage-gated calcium channels
José Omar; Hernández-Hernández, Oscar; Chirinos, Mayel; González-González, María Elena; Larrea, Fernando; Almanza, Angélica; Felix, Ricardo; Darszon, Alberto; Treviño, Claudia L.
Follow Biochemical and Biophysical Research Communications , Volume 395 (4)
Elsevier – May 14, 2010not fully understood mechanisms. Even in mouse sperm, the pharmacologically documented participation of voltage-gated Ca 2+ (Ca V ) channels and store-operated channels (SOCs) in the ZP-induced AR is being ...
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Progesterone activates the principal Ca 2+ channel of human sperm
Lishko, Polina V.; Botchkina, Inna L.; Kirichok, Yuriy
Follow Nature , Volume 471 (7338)
Nature Publishing Group (NPG) – Mar 16, 2011developed method for patch-clamping completely mature ejaculated human spermatozoa .Under normal physiological conditions, mouse and human CatSper channels are Ca 2+ selective, but pass monovalent ions (Cs ...
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Gamete membrane microdomains and their associated molecules in fertilization signaling
Hasan, A.K.M. Mahbub; Fukami, Yasuo; Sato, Ken‐ichi
Follow Molecular Reproduction & Development , Volume 78 (10‐11)
Wiley – Jun 17, 2011in B lymphocytes; and ion channels and receptors for certain hormones (e.g., β‐adrenergic receptor), growth factors (e.g., epidermal growth factor receptor), and neurotransmitters (e.g., dopamine ...
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Patch‐clamp ‘mapping’ of ion channel activity in human sperm reveals regionalisation and co‐localisation into mixed clusters
Jiménez‐González, M.C.; Gu, Y.; Kirkman‐Brown, J.; Barratt, C.L.R.; Publicover, S.
Follow Journal of Cellular Physiology , Volume 213 (3)
Wiley – Sep 26, 2007Ion channels are pivotal to many aspects of sperm physiology and function. We have used the patch clamp technique to investigate the distribution of ion channels in the plasma membrane of the head ...
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The CatSper channel mediates progesterone-induced Ca 2+ influx in human sperm
Goodwin, Normann; Brenker, Christoph; Kashikar, Nachiket D.; Weyand, Ingo; Seifert, Reinhard; Strünker, Timo; Kaupp, U. Benjamin
Follow Nature , Volume 471 (7338)
Nature Publishing Group (NPG) – Mar 16, 2011reveal an alkaline-activated current carried by mono- and divalent ions that exhibits all the hallmarks of sperm-specific CatSper Ca 2+ channels . Progesterone substantially enhances the CatSper current ...
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Proteomic profiling reveals compartment‐specific, novel functions of ascidian sperm proteins
Nakachi, Mia; Nakajima, Ayako; Nomura, Mamoru; Yonezawa, Kouki; Ueno, Keisuke; Endo, Toshinori; Inaba, Kazuo
Follow Molecular Reproduction & Development , Volume 78 (7)
Wiley – Jun 27, 2011were mostly those for glycolysis. Several of these proteins have been reported to be involved in axoneme signal transduction in C. intestinalis sperm, including the activation of ion channels, adenylate ...
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Spermatozoa of Sharpsnout sea bream ( Diplodus puntazzo ) and European sea bass ( Dicentrarchus labrax ) express opioid receptors
Aiudi, G.; Bucci, F.A.; De Sandro Salvati, A.; Guaricci, A.C.; Albrizio, M.
Follow Aquaculture , Volume 309 (1)
Elsevier – Nov 22, 2010of intracellular calcium ion that is required to activate sperm motility after spawning. In mammals OR are functionally associated to calcium channels and in fishes calcium is highly required for fish sperm ...
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