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of NO and peroxynitrite is presented in detail in this review. I. INTRODUCTION Nitric oxide (NO) is an omnipresent intercellular messenger in all vertebrates, modulating blood flow, thrombosis, and neural ...
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nitric oxide (NO) signaling and skeletal muscle IGF-I expression has not been established. However, dystrophic muscle, in which neuronal NO synthase (nNOS) protein is not associated with the sarcolemma ...
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of NO from L -arginine and O 2 is catalyzed by nitric oxide synthases (NOS) ( 92 ). There exist three canonical isoforms [neuronal (NOS I or nNOS), inducible (NOS II), and endothelial (NOS III ...
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-specific expression of endothelial nitric oxide synthase (eNOS). This review investigates the involvement of epigenetic regulatory mechanisms in vascular endothelial cell-specific gene expression using eNOS ...
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of the “indirect” hypothesis of microglial activation-induced cell death, the inhibition of nitric oxide synthase decreases the induction of apoptosis in Ctsd -deficient mouse brain [83,106] . A decrease in phospho ...
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isoform of the enzyme nitric oxide synthase. The expression of endothelial nitric oxide synthase in the lung increases dramatically during late gestation, optimizing the capacity for nitric oxide production ...
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Nitric oxide (NO) produced by NO synthases (NOS) regulates a wide range of cellular functions. Analysis by gene arrays provides valuable information for identifying important elements of the cellular ...
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receptor 2 mtNOS mtPTP NMDA nNOS NOS PD PP PS1 QR2 RBD RNS ROS SCN SOD Tg TNF-R1 TNF-a VEGF VIP Mitocndrial nitric oxide synthase Mitocndrial permeability transition pore N-methyl-D-aspartate Neuronal nitric ...
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to stimulate activity; and another that is a high-output, inducible enzyme [inducible nitric oxide synthase (iNOS), type II NOS] for which activity is independent of a calcium trigger. The high levels ...