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development.—Tripathi, G., Salih, D. A. M., Drozd, A. C., Cosgrove, R. A., Cobb, L. J., Pell, J. M. IGF-independent effects of insulin-like growth factor binding protein-5 ( Igfbp5 ) in vivo. Abstract ...
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We have demonstrated previously that insulin‐like growth factor binding protein (IGFBP)‐3 alone has little growth inhibitory effect on Hs578T human breast cancer cells, but that it can dramatically ...
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this mechanism, microarray analysis was performed using Mxi1+/+ and Mxi1−/− MEFs. The microarray analysis focused on insulin-like growth factor binding protein-3 (IGFBP-3).Insulin-like growth factor-I (IGF-I ...
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of Manitoba Winnipeg R3E 0W3 Canada Abstract Insulin-like growth factor binding protein-3 (IGFBP-3) inhibits the replication and promotes apoptosis in various cell lines in an IGF-independent manner. We ...
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THAT the insulin-like growth factors (IGF-I and IGF-II) are critical regulators of bone metabolism and that the family of six structurally similar IGF-binding proteins (IGFBPs) have tremendous influence over ...
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in prostate cancer [12] . Taken together, these studies strongly support that NF-κB plays an important role in prostate tumor progression.The insulin-like growth factor binding proteins (IGFBPs ...
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Abstract In human intestinal smooth muscle cells, endogenous insulin-like growth factor-I (IGF-I) regulates growth and IGF-binding protein-5 (IGFBP-5) expression. The effects of IGF-I are facilitated ...
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of bone growth control, insulin‐like growth factors (IGFs) have been studied extensively for more than 50 years and are important in many facets of normal physiology, growth, and development (reviewed ...
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Background: The objective of the present study is to explore the association between zinc concentrations and insulin-like growth factor 1 (IGF-1), its binding protein (IGFBP-3) and total prostate ...
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discusses the relationship between the insulin‐like growth factor (IGF) axis and cell‐surface integrin receptors in the regulation of various aspects of cell physiology. Key to these interactions are signals ...
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