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in the pathobiology of erythrocyte-based vascular signaling.—Rogers, S. C., Said, A., Corcuera, D., McLaughlin, D., Kell, P., Doctor, A. Hypoxia limits antioxidant capacity in red blood cells by altering glycolytic ...
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oxidative stress parameters were notably decreased after CPAP. Intracellular glutathione and mitochondrial membrane potential increased significantly. Also, total antioxidant capacity and most of the plasma ...
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maximal aerobic capacity. Thus, in conditions of hypoxia, a rigidiï¬cation of RBC may represent a limiting factor for muscle oxygen supply and thus impair performance. RBC stiffening has also been shown ...
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Objective: Glutathione is a natural antioxidant in the fetus and adult. We sought to determine whether maternal hypoxia alters glutathione levels in fetal organs as an adaptive response ...
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hypoxia-tolerant animals exhibit increased blood O2 carrying capacity, which is caused by increased red blood cell (RBC) mass and blood volume. The high body mass of most diving mammals can also ...
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; blood flow regulationTHE ENDOTHELINS ARE POTENT vasoconstrictor peptides released by endothelial cells in response to a variety of stimuli. Hypoxia is a particularly potent activator of endothelin-1 ...
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Korean red ginseng prevents cell death and enhances recovery in ischemic stroke mediating PI3K/Akt pathway S.-Y. Cheon, K.J. Cho, H.-W. Kim, S.K. Lee, S.-H. Lee, J.E. Lee, B.I. Lee and G.W. Kim Yonsei ...
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, such a mechanism should also operate in response to fatty acids (an additional source of NADH), as was shown in endothelial cells ( 306 ). Increasing antioxidant capacity or decreasing mitochondrial superoxide ...
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differentiation of erythroid precursors and accelerating the release of reticulocytes from the bone marrow, resulting in an increase in red blood cell mass ( 84 ). Recombinant Epo therapy has been shown to directly ...
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transcripts. D. Tissue Distribution The inducible form of heme oxygenase, HO-1, occurs at a high level of expression in the spleen and other tissues that degrade senescent red blood cells, including ...
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