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Did you mean: human defensive and ll 37 in mucosal immunity
for: human defensins and ll 37 in mucosal immunity
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Human defensins and LL-37 in mucosal immunity
Doss, Mona; White, Mitchell R.; Tecle, Tesfaldet; Hartshorn, Kevan L.
Follow Journal of Leukocyte Biology , Volume 87 (1): 79
Fed of American Socs for Experimental Biology – Jan 1, 2010secretions. retrocyclin innate immunity Introduction This review will focus specifically on the role of defensins and the antimicrobial peptide LL-37 in human mucosal immunity. There have been ...
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The human cathelicidin hCAP18/LL-37: A multifunctional peptide involved in mycobacterial infections
Méndez-Samperio, Patricia
Follow Peptides , Volume 31 (9)
Elsevier – Sep 1, 2010, indicating that the immunomodulatory activity of this peptide can be augmented by other immune mediators [113] . Moreover, it is well known that in humans, LL-37, in cooperation with other cationic ...
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Impact of LL-37 on anti-infective immunity
Bowdish, Dawn M. E.; Davidson, Donald J.; Lau, Y. Elaine; Lee, Ken; Scott, Monisha G.; Hancock, Robert E. W.
Follow Journal of Leukocyte Biology , Volume 77 (4): 451
Fed of American Socs for Experimental Biology – Apr 1, 2005lysosomes, intestinal crypts, and psoriatic skin, we are not aware of any conclusive evidence suggesting that LL-37 and other peptides (including defensins) can directly kill bacteria at mucosal surfaces ...
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Paneth cell α-defensins in enteric innate immunity
André, Ouellette
Follow Cellular and Molecular Life Sciences , Volume 68 (13)
Springer Journals – Jul 1, 2011]. The biology of defensins as immunomodulatory molecules in the innate and adaptive immune responses have been widely reported and reviewed [38â45] and will not be considered here. Human Paneth cells produce ...
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PU.1 and bacterial metabolites regulate the human gene CAMP encoding antimicrobial peptide LL-37 in colon epithelial cells
Termén, Stefan; Tollin, Maria; Rodriguez, Eduardo; Sveinsdóttir, Sigrún H.; Jóhannesson, Bjarki; Cederlund, Andreas; Sjövall, Jan; Agerberth, Birgitta; Gudmundsson, Gudmundur H.
Follow Molecular Immunology , Volume 45 (15)
Elsevier – Sep 1, 2008, the human enteric pathogens Shigella dysenteriae and Vibrio cholerae downregulate expression of LL-37 and β-defensin-1, suggesting a means of facilitating infection ( Islam et al., 2001 ).The interest ...
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Shigella are versatile mucosal pathogens that circumvent the host innate immune system
Ashida, Hiroshi; Ogawa, Michinaga; Mimuro, Hitomi; Kobayashi, Taira; Sanada, Takahito; Sasakawa, Chihiro
Follow Current Opinion in Immunology , Volume 23 (4)
Elsevier – Aug 1, 2011-activated protein kinases (MAPK), leading to the secretion of pro-inflammatory cytokines, chemokines (e.g. IL-8 and TNF-α), and antimicrobial peptides (e.g. β-defensin and LL-37). These molecules stimulate ...
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Roles of human β-defensins in innate immune defense at the ocular surface: arming and alarming corneal and conjunctival epithelial cells
Fabian, Garreis; Thomas, Schlorf; Dieter, Worlitzsch; Philipp, Steven; Lars, Bräuer; Kristin, Jäger; Friedrich, Paulsen
Follow Histochemistry and Cell Biology , Volume 134 (1)
Springer Journals – Jul 1, 2010Human β-defensins are cationic peptides produced by epithelial cells that have been proposed to be an important component of immune function at mucosal surfaces. In this study, the expression ...
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Development of novel LL-37 derived antimicrobial peptides with LPS and LTA neutralizing and antimicrobial activities for therapeutic application
Nell, Marja J.; Tjabringa, G. Sandra; Wafelman, Amon R.; Verrijk, Ruud; Hiemstra, Pieter S.; Drijfhout, Jan W.; Grote, Jan J.
Follow Peptides , Volume 27 (4)
Elsevier – Apr 1, 2006in humans. Based on the sequence of the human antimicrobial peptide LL-37 we developed and investigated length variants, substitution analogues and modifications to stabilize the peptides to prevent enzymatic ...
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Intestinal epithelial barrier and mucosal immunity
C., Müller; I., Autenrieth; A., Peschel
Follow Cellular and Molecular Life Sciences , Volume 62 (12)
Springer Journals – Jun 1, 2005; stimulates epithelial wound healing; angiogenic; neutralizes LPS neutralizes LPS; opsonic Additional activities a-Defensins HD-5, HD-6 b-Defensins HBD1, HBD2, HBD3, HBD4 Cathelicidin LL-37/hCAP-18 Bactericidal ...
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Human antimicrobial proteins in ear wax
M., Schwaab; A., Gurr; A., Neumann; S., Dazert; A., Minovi
Follow European Journal of Clinical Microbiology Infectious Diseases , Volume 30 (8)
Springer Journals – Aug 1, 2011, vancomycin-resistant Enterococcus faecium, Candida albicans and Haemophilus influenza [9, 12, 17]. Human LL-37 (LL-37) LL-37 is the 37-amino-acid-long C-terminus and the antimicrobial active component ...
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