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for: functional characterization of a promoter polymorphism that drives
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Functional characterization of a promoter polymorphism that drives ACSL5 gene expression in skeletal muscle and associates with diet-induced weight loss
Teng, Allen C. T.; Adamo, Kristi; Tesson, Frédérique; Stewart, Alexandre F. R.
Follow The FASEB Journal , Volume 23 (6): 1705
Fed of American Socs for Experimental Biology – Jun 1, 2009., Stewart, A. F. R. Functional characterization of a promoter polymorphism that drives ACSL5 gene expression in skeletal muscle and associates with diet-induced weight loss. Abstract Diet-induced ...
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Functional genetic polymorphisms in interleukin-12B gene in association with systemic lupus erythematosus
Lyuba, Miteva; Irena, Manolova; Mariana, Ivanova; Rasho, Rashkov; Rumen, Stoilov; Maya, Gulubova; Spaska, Stanilova
Follow Rheumatology International , Volume 32 (1)
Springer Journals – Jan 1, 2012of two functional polymorphisms in cis -regulatory regions of IL12B gene in the susceptibility and clinical symptoms of SLE in Bulgarian patients. Female SLE patients ( n = 141) and 124 healthy women were ...
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Functional characterization of three single‐nucleotide polymorphisms present in the human APOE promoter sequence: Differential effects in neuronal cells and on DNA–protein interactions
Maloney, Bryan; Ge, Yuan‐Wen; Petersen, Ronald C.; Hardy, John; Rogers, Jack T.; Pérez‐Tur, Jordi; Lahiri, Debomoy K.
Follow American Journal of Medical Genetics part B , Volume 153B (1)
Wiley – Dec 21, 2009connection among APOE promoter polymorphisms' associations with AD to functional promoter activity differences and specific changes in DNA–protein interactions in cell culture‐based assays. Taken together ...
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TNF promoter polymorphisms associated with muscle phenotypes in humans
Liu, Dongmei; Metter, E. Jeffrey; Ferrucci, Luigi; Roth, Stephen M.
Follow Journal of Applied Physiology , Volume 105 (3): 859
The American Physiological Society – Sep 1, 2008Tumor necrosis factor-α (TNF-α) is a potent catabolic factor to skeletal muscle. Single-nucleotide polymorphisms (SNPs) in the promoter region of the TNF-α coding gene, TNF , have been implicated ...
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HvFT1 ( VrnH3 ) drives latitudinal adaptation in Spanish barleys
Ana, Casas; Abderrahmane, Djemel; Francisco, Ciudad; Samia, Yahiaoui; Luis, Ponce; Bruno, Contreras-Moreira; M., Gracia; José, Lasa; Ernesto, Igartua
Follow TAG Theoretical and Applied Genetics , Volume 122 (7)
Springer Journals – May 1, 2011polymorphisms have been proposed, but experimental evidence of their role on agronomic performance and adaptation is needed. We examined allelic variation at the promoter and intron 1 of the HvFT1 gene ...
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Functional profiling of uncommon VCAM1 promoter polymorphisms prevalent in African American populations
Idelman, Gila; Taylor, James G.; Tongbai, Ron; Chen, Renee A.; Haggerty, Cynthia M.; Bilke, Sven; Chanock, Stephen J.; Gardner, Kevin
Follow Human Mutation , Volume 28 (8)
Wiley – Jul 17, 2007by chromatin immunoprecipitation. This report provides the first functional evaluation of VCAM1 promoter polymorphisms and establishes a hypothetical foundation for investigation of their role ...
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Altered TNF-α and IFN-γ levels associated with PD1 but not TNFA polymorphisms in patients with chronic HBV infection
Zhang, Guoyu; Li, Zhu; Han, Qunying; Li, Na; Zhu, Qianqian; Li, Fang; Lv, Yi; Chen, Jinghong; Lou, Sai; Liu, Zhengwen
Follow Infection, Genetics and Evolution , Volume 11 (7)
Elsevier – Oct 1, 2011associated with the polymorphisms have not been well characterized in most of the studies. This leads to incomplete reflection of the associations between gene polymorphisms studied and their final effects ...
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Dopamine polymorphisms and depressive symptoms predict foods intake. Results from a nationally representative sample
Agurs-Collins, Tanya; Fuemmeler, Bernard F.
Follow Appetite , Volume 57 (2)
Elsevier – Oct 1, 2011>Introduction A depressive episode is characterized by depressed mood and a loss of interest in pleasurable activities. Clinical depression and depressive symptoms, for some, are also associated ...
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Therapeutic targeting of the IL-12/23 pathways: generation and characterization of ustekinumab
Sachs, Clifford W; Treacy, George; Zhou, Honghui; Pendley, Charles E; Brodmerkel, Carrie M; Shankar, Gopi; Mascelli, Mary A; Benson, Jacqueline M
Follow Nature Biotechnology , Volume 29 (7)
Nature Publishing Group (NPG) – Jul 11, 2011to their induction and the effector cytokines that they produce . IL-12 signaling concurrent with antigen presentation drives CD4 + T-cell differentiation toward the T H 1 phenotype, which is characterized by activity ...
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Identification and functional analysis of SOX10 missense mutations in different subtypes of waardenburg syndrome
Chaoui, Asma; Watanabe, Yuli; Touraine, Renaud; Baral, Viviane; Goossens, Michel; Pingault, Veronique; Bondurand, Nadege
Follow Human Mutation , Volume 32 (12)
Wiley – Sep 19, 2011mutations described to date and not previously characterized in terms of function were analyzed.Materials and Methods SOX10 Mutation Screening Informed consent for genetic testing ...
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