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for: fatty acid binding protein 4 is a target of vegf and a regulator of
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Fatty acid binding protein 4 is a target of VEGF and a regulator of cell proliferation in endothelial cells
Elmasri, Harun; Karaaslan, Cagatay; Teper, Yaroslav; Ghelfi, Elisa; Weng, MeiQian; Ince, Tan A.; Kozakewich, Harry; Bischoff, Joyce; Cataltepe, Sule
Follow The FASEB Journal , Volume 23 (11): 3865
Fed of American Socs for Experimental Biology – Nov 1, 2009in ECs.—Elmasri, H., Karaaslan, C., Teper, Y., Ghelfi, E., Weng, M., Ince, T. A., Kozakewich, H., Bischoff, J., Cataltepe, S. Fatty acid binding protein 4 is a target of VEGF and a regulator of cell ...
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Vascular endothelial growth factor B controls endothelial fatty acid uptake
Hagberg, Carolina E.; Falkevall, Annelie; Wang, Xun; Larsson, Erik; Huusko, Jenni; Nilsson, Ingrid; van Meeteren, Laurens A.; Samen, Erik; Lu, Li; Vanwildemeersch, Maarten; Klar, Joakim; Genove, Guillem; Pietras, Kristian; Stone-Elander, Sharon; Claesson-Welsh, Lena; Ylä-Herttuala, Seppo; Lindahl, Per; Eriksson, Ulf
Follow Nature , Volume 464 (7290)
Nature Publishing Group (NPG) – Mar 14, 2010(FATPs), the fatty acid binding proteins, or the scavenger receptor CD36 (ref. 4 ). Treatment of endothelial cells with either of the VEGF-B splice isoforms , VEGF-B 167 or VEGF-B 186 , increased both ...
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Targeting podocyte-associated diseases
Leeuwis, Jan Willem; Nguyen, Tri Q.; Dendooven, Amélie; Kok, Robbert J.; Goldschmeding, Roel
Follow Advanced Drug Delivery Reviews , Volume 62 (14)
Elsevier – Nov 30, 2010, the fact that many of the slit diaphragm proteins are phosphorylated contributes a charge-selective element.Proteins making up the slit diaphragm include nephrin, podocin, Neph1, Neph2, fatty acid ...
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Targeting the protein kinase C family in the diabetic kidney: lessons from analysis of mutant mice
M., Meier; J., Menne; H., Haller
Follow Diabetologia , Volume 52 (5)
Springer Journals – May 1, 2009Mitogen-activated kinase NEFA Non-esterified fatty acid nPKC Novel protein kinase C PKC-DMES PKC-β Inhibitor Diabetic Macular Edema Study PKC-DRS PKC-β Inhibitor Diabetic Retinopathy Study PKC Protein ...
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Gallic acid indanone and mangiferin xanthone are strong determinants of immunosuppressive anti-tumour effects of Mangifera indica L. bark in MDA-MB231 breast cancer cells
García-Rivera, Dagmar; Delgado, René; Bougarne, Nadia; Haegeman, Guy; Vanden Berghe, Wim
Follow Cancer Letters , Volume 305 (1)
Elsevier – Jun 1, 2011of NFκB target genes involved in inflammation, metastasis, anti-apoptosis and angiogenesis, such as IL-6, IL-8, COX2, CXCR4, XIAP, bcl2, VEGF. The cumulative NFκB inhibition by gallic acid ...
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Using drug-excipient interactions for siRNA delivery
Bruno, Katharina
Follow Advanced Drug Delivery Reviews , Volume 63 (13)
Elsevier – Oct 1, 2011, can also function as regulator of gene expression, has led to a quantum leap in understanding gene regulation. RNA molecules can inhibit protein translation either by binding to complementary messenger ...
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Role of Chitin and Chitinase//Chitinase-Like Proteins in Inflammation, Tissue Remodeling, and Injury
Lee, Chun Geun; Da Silva, Carla A.; Dela Cruz, Charles S.; Ahangari, Farida; Ma, Bing; Kang, Min-Jong; He, Chuan-Hua; Takyar, Seyedtaghi; Elias, Jack A.
Follow Annual Review of Physiology , Volume 73
Annual Reviews – Mar 17, 2011of chitinases and chitinase-like proteins (C//CLPs) have been identified. However, their roles have only recently begun to be elucidated. Acidic mammalian chitinase (AMCase) inhibits chitin-induced innate ...
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Lysophosphatidic acid up-regulates vascular endothelial growth factor-C and lymphatic marker expressions in human endothelial cells
C.-I., Lin; C.-N., Chen; M.-T., Huang; S.-J., Lee; C.-H., Lin; C.-C., Chang; H., Lee
Follow Cellular and Molecular Life Sciences , Volume 65 (17)
Springer Journals – Sep 1, 2008. Lysophosphatidic acid (LPA) is a lowmolecular-weight lipid growth factor, which binds to G-protein-coupled receptors. Previous studies have shown that LPA enhances vascular endothelial growth factor-A (VEGF ...
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Liver Kinase B1 ( LKB1 ) in the pathogenesis of epithelial cancers
Herrmann, Jennifer L.; Byekova, Yevgeniya; Elmets, Craig A.; Athar, Mohammad
Follow Cancer Letters , Volume 306 (1)
Elsevier – Jul 1, 2011LKB1 acts as a master kinase, with its major protein targets being the family of AMPKs. Through activation of multiple signaling pathways, LKB1’s main physiologic functions involve regulating ...
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Inhibition of endothelial cell proliferation and angiogenesis by orlistat, a fatty acid synthase inhibitor
Browne, Cecille D.; Hindmarsh, Elizabeth J.; Smith, Jeffrey W.
Follow The FASEB Journal , Volume 20 (12): 2027
Fed of American Socs for Experimental Biology – Oct 1, 2006by orlistat, a fatty acid synthase inhibitor. Key Words: VEGF • KDR • neovascularization Orlistat, an antiobesity drug, is cytostatic and cytotoxic to tumor cells (1). The antitumor activity of orlistat can ...
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