Did you mean: enhancement of learning and memory in mice by a benzodiazepines
More Like This 8OiF1d8i30 Preview Only
More Like This 2nEbYvLONT Rentable
Highlights ► Diazepam and flunitrazepam impaired memory in mice, in the elevated plus-maze task. ► NOS inhibitors prevented flunitrazepam-induced memory impairment. ► NOS inhibitors enhanced diazepam ...
More Like This 2crgIm5V0j Rentable
progestin receptors (PRKO), or wildtype mice were administered progesterone (10 mg/kg, SC), or vehicle, and learning/memory was evaluated. Progesterone, compared to vehicle, produced a conditioned place ...
More Like This OUa6AQsrMw Rentable
, such as fear and aversion, can modulate, by enhancing or impairing, memory formation [22] . Because the available animal models of learning and memory have a limited ability to detect the effects of drugs ...
More Like This cGxXy3c6vd Rentable
to subchronic benzodiazepine treatment, GluR-A subunit-deficient mice were rendered tolerant by a high-dose seven-day flurazepam treatment (40 mg/kg, s.c., twice a day for 4 days, 60 mg/kg twice a day for 3 days ...
More Like This mihBuMzdpF Rentable
but not active avoidance learning task in rats, showed no effect on anxiety or muscle tone, and had no convulsive activity in the tested dose range (2–20 mg/kg) [23] . In mice, PWZ-029 at a dose of 10 mg/kg ...
More Like This X0LIm176Ys Rentable
[1,31] so much so that enhanced recognition memory will impinge negatively on later learning and impair behavioural flexibility. Indeed, we here report a dose-dependent increase in sociability after ...
More Like This TK9N6jiNHN Rentable
of the food reinforcers used. Benzodiazepines can enhance the palatability of food (Berridge and Pecina 1995; Cooper 1980) and might modify extinction through increases in sensitivity to food reinforcement ...
More Like This UrEy5TQrv3 Rentable
discrimination; SCD) in a four-hole-board. Animals submitted to SCD were also evaluated for emotional reactivity in an elevated-plus maze. Methods: Mice were injected before the learning session began ...
More Like This TCNQlS3qZy Rentable
). As a consequence, drugs that facilitate fear extinction may be useful as novel treatments for PTSD. The N-methyl d -aspartate (NMDA) receptor may play an important role in learning and memory and in experience ...