Did you mean: endothelial cell nadph oxidase mediated the cerebral microvascular
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in cerebral vascular endothelium have not been identified. The present study using primary cultures of cerebral vascular endothelial cells addresses the hypotheses that 1 ) Nox4 NADPH oxidase is the primary ...
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-A receptor antagonist, bicuculline, resulted in increased levels of MMP-9 [32]. We showed that MC inhibits MMP activation in microvascular endothelial cells [33]. Others have suggested that GABA inhibits cell ...
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was regulated by c‐Src or c‐Src activated‐NADPH oxidase/ROS. J. Cell. Physiol. 225: 741–750, 2010. © 2010 Wiley‐Liss, Inc. Cerebral endothelial disruption induced by oxidative stress (Yachie et al., 1999 ; Ryter ...
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(TNF-α) in cerebral microvascular endothelial cells (CMVEC) from newborn piglets. Nox4 is the major isoform of NADPH oxidase responsible for TNF-α-induced oxidative stress and apoptosis in CMVEC. We ...
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by alveolar macrophages stimulated by hypoxia and transported by the circulation. Circulating MCP-1, in turn, activates perivascular mast cells to initiate the microvascular inflammatory cascade. The research ...
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from subjects without AL and induce apoptotic injury in human coronary artery endothelial cells (HCAEC) and 2 ) explore potential mechanisms underlying LC-induced microvascular dysfunction and injury. ...
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and in vitro . We also investigated the effects of angiotensin II (AngII) on leukocyte function in relation to NO production. Leukocyte–endothelial cell adhesion in brain microvessels was investigated ...
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microvascular endothelial cells based on blunted proliferation in cells treated with inhibitors of NADPH oxidase or transgenic mice deficient in NADPH oxidase ( 1 , 31 ). Accordingly, we tested the capacity ...
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; Lima et al., 2009 ); however, little is known about the potential mechanisms responsible for GSNO-mediated oxidative challenge in endothelial cells.The details of GSNO in cytotoxicity may aid ...