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Did you mean: discovery of a functional receptor tyrosine based switch motif
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, A., Laburthe, M. Discovery of a functional immunoreceptor tyrosine-based switch motif in a 7-transmembrane-spanning receptor: role in the orexin receptor OX1R-driven apoptosis. Abstract The orexin ...
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-proximal motif (LHYASL) conforms to the canonical immunoreceptor tyrosine–based inhibitory motif (I/L/V)xYxx(L/V), whereas the distal motif (TEYSEI) resembles the immunoreceptor tyrosine–based switch motif ...
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cytoplasmic immunoreceptor tyrosine-based switch motifs (ITSM; TxYxxV/I) and include 2B4 (CD244), CD84, CD229, NTB-A, and CS1. All of these molecules have been shown to modify lymphocyte function, and many ...
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potentially mediate immunostimulatory effects of ß-glucans. Dectin-1 contains an immunoreceptor tyrosine-based activation motif in its cytoplasmic tail, thus ligand recognition may lead to activation ...
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in osteoclast precursor cells, we found that immunoreceptor tyrosine-based activation motif (ITAM) signaling mediated by dual membrane adaptors, Fc receptor (FcR) common\gamma subunit (FcR\gamma) and DNAX ...
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--regulated kinase guanine-nucleotide-exchange factor hen egg lysozyme inositol 1,4,5-trisphosphate immunoreceptor tyrosine-based c-Jun amino-terminal klnase mitogen-activated protein klnase membrane ...
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