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and morphogenesis.—Paulhe, F., Wehrle-Haller, M., Jacquier, M.-C., Imhof, B. A., Tabone-Eglinger, S., Wehrle-Haller, B. Dimerization of Kit-ligand and efficient cell-surface presentation requires a conserved Ser-Gly ...
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In the present study, detailed information is presented on the hetero-dimerization of the serotonin 5-HT 2A receptor and the dopamine D 2 receptor. Biophysical approaches (fluorescence spectroscopy ...
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variants and confirmed by FRET analysis in live cells. The present study clearly demonstrates the existence of preformed but inactive gp130/LIF-R hetero- and gp130/gp130 homo-dimers. The addition of ligand ...
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We previously showed that integrin αvβ3 expression upon engagement by its major ligand vitronectin (VN) correlated with enhanced human ovarian cancer cell adhesion, motility, and proliferation ...
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follicle-stimulating hormone receptor (FSHR) mutants exert dominant negative actions on wild-type FSHR cell surface membrane expression. Co-transfection of constant amounts of wild-type receptor cDNA ...
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to exist in three states at the cell surface: an encrypted form that is inactive, the pro‐coagulant form that rapidly binds its ligand FVIIa to initiate the coagulation cascade and a signaling form ...
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ability to bind to d -Ala- d -Ala terminated peptides present in the cell wall of Gram-positive bacteria. Here, we show that conjugation of vancomycin to PLL- g -PEG prevents its action as an antibiotic ...
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on mucosal surfaces. The synthesis of sIgA in vivo involves two different cell types: B‐lymphocytes that produce and secrete dimeric IgA (dIgA), and polarized epithelial cells that mediate transcytosis from ...
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TLR1 (MIM♯ 601194), TLR2 (MIM♯ 603028), TLR4 (MIM♯ 603030), TLR5 (MIM♯ 603031), and TLR6 (MIM♯ 605403) are generally expressed on the cell surface. Intracellular TLRs sense nucleic acid agonists ...
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sequences of KL in biosynthetic processing and cell surface presentation. The normal KL protein products are processed for cell surface expression, where they form dimers. Both Sl 17H and the cytoplasmic ...
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