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, A. Differential contribution of SNARE-dependent exocytosis to inflammatory potentiation of TRPV1 in nociceptors. Abstract Potentiation of the pain-integrator ion channel transient receptor potential ...
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of α-synuclein, and evidence linking it to Rab-regulated neuronal trafficking and SNAREs in synaptic vesicle exocytosis. We shall table the unanswered questions and speculate on future perspectives.2 ...
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complexes containing open syntaxin-1. Understanding which steps in fusion depend on the latter interaction and whether Munc18-1 competes with other factors such as complexins for SNARE complex binding ...
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The present study involves the testing and characterization of synaptic vesicle (SV) docking and fusion as the steps of exocytosis using two different approaches in vitro. The interaction of SVs ...
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) proteins located on the external surface of vesicles, and t-SNAREs, partner proteins located on the cytosolic face of the target membrane (the plasma membrane in the case of exocytosis) (Hay and Scheller ...
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unveiled. In this review, we discuss both the PKA-dependent and the PKA-independent pathways of cAMP-regulated exocytosis and suggest a mechanism of differential implementation of these two pathways within ...
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-associated Sed5p allows efficient formation of SNARE complexes and contributes to the specificity of SNARE complex assembly [117]. A similar, N-terminal peptide motif-dependent binding was also observed ...
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an interaction between caveolin1 and SNAREs (soluble N-ethylmalemide-sensitive factor attachment protein receptor) which may contribute to the cellular mechanisms underlying changes in synaptic strength ...
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, the fusion of secretory vesicles with the plasma membrane, employs the proteins syntaxin and SNAP-25 as plasma membrane SNAREs. As a result, exocytosis is dependent upon the targeting of these proteins ...
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exocytosis, discussing their possible involvement in the control of the Ca 2+ -dependent processes regulating exocytosis like vesicle depletion and vesicle recycling. T-type channels are transient low-voltage ...
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